专利号:US-2006052356-A1 优先权日:2004-09-03 标 题:Pharmacological methods to modulate oxygen consumption 发明人:WARD KEVIN R; BARBEE R W; REYNOLDS PENNY; DIEGLEMANN ROBERT; KUKREJA RAKESH; SPIESS BRUCE; EVANS MELISSA; EDWARDS ERIC 权利人:WARD KEVIN R; BARBEE R W; REYNOLDS PENNY; DIEGLEMANN ROBERT; KUKREJA RAKESH; SPIESS BRUCE; EVANS MELISSA; EDWARDS ERIC 摘要:Methods of modulating oxygen consumption in tissues are provided. In particular, the methods involve the administration of agents that transiently inhibit protein synthesis. The methods are used to treat ischemia and reperfusion-related injuries by temporarily decreasing oxygen consumption needs, and/or by inhibiting inflammation that results from reperfusion.
1: Nadeson R, Goodchild CS. Antinociceptive properties of neurosteroids III: experiments with alphadolone given intravenously, intraperitoneally, and intragastrically. Br J Anaesth. 2001 May;86(5):704-8. Danish.
合成参考文献
摘要:Proceedings of the European Society of Toxicology., 16(208), 1975 摘要:Kleemann, A.; Engel, J.; Kutscher, B.; Reichert, D., Pharmaceutical Substances[Online], Thieme: Stuttgart, (2003).