CAS: 16932-45-9; 2-Bromo-1,3-Dimethoxybenzene

相似化合物

135999-16-5 17715-69-4 1131-40-4

上下游产品

2-溴邻苯二酚 2-Bromoresorcinol 6751-75-3
间苯二甲醚 1,3-Dimethoxybenzene 151-10-0

间苯二甲醚置于正丁基锂,2,3-二溴氟苯体系中,用 四氢呋喃,正己烷 用作溶剂,化学反应 5.0H,以88%的收率获得1-溴-2,6-二甲氧基苯
参考文献:芳基锂与官能化 1,2-二溴苯的芳炔交叉偶联的区域选择性
标题:芳基锂与官能化 1,2-二溴苯的芳炔交叉偶联的区域选择性
摘要:通过以 1,3-二甲氧基苯和功能化的 1,2-二溴苯为起始原料的芳炔交叉偶联反应,已经合成了三和四取代的邻溴联芳基化合物,产率非常好.本研究概述了 1,2-二溴苯前体以及反应温度对芳基-芳基键形成结果的影响,并指出了在不对称苄前体的情况下,结构参数(电子效应,空间位阻,温度等)控制芳炔交叉偶联反应的区域选择性.
Doi:10.1002/ejoc.201001283

专利信息

专利号:US-10544177-B2
优先权日:2016-12-06
标 题:Chiral dihydrobenzooxaphosphole ligands and synthesis thereof
发明人：DESROSIERS JEAN-NICOLAS; FANDRICK DANIEL ROBERT; HADDAD NIZAR; LI GUISHENG; PATEL NITINCHANDRA D; QU BO; RODRIGUEZ SONIA; SENANAYAKE CHRIS HUGH; SIEBER JOSHUA DANIEL; TAN ZHULIN; WANG XIAO-JUN; YEE NATHAN K; ZHANG LI; ZHANG YONGDA
权利人:BOEHRINGER INGELHEIM INT
摘要:This invention relates to novel phosphorous ligands useful for organic transformations. Methods of making and using the ligands in organic synthesis are described. The invention also relates to processes for preparing the novel ligands.

专利号:US-7615634-B2
优先权日:2003-02-10
标题:4-aminopyrimidine-5-one derivatives
发明人：BARTKOVITZ DAVID JOSEPH; CHU XIN-JIE; DING QINGJIE; JIANG NAN; LOVEY ALLEN JOHN; MOLITERNI JOHN ANTHONY; MULLIN JR JOHN GUILFOYLE; VU BINH THANH; WOVKULICH PETER MICHAEL
权利人:HOFFMANN LA ROCHE
摘要:Novel intermediate compounds are disclosed. These compounds are useful in the synthesis of 4-aminopyrimidine-5-one derivatives that inhibit cyclin-dependent kinases, in particular cyclin-dependent kinase 4 (Cdk4). The 4-aminopyrimidine-5-one derivatives and their pharmaceutically acceptable salts have antiproliferative activity and are useful in the treatment or control of cancer, in particular solid tumors.

专利号:US-6399653-B1
优先权日:1996-06-18
标题 :Ring fused dihydropyrans, process for preparation and use thereof
发明人：HENKE STEPHAN
权利人:HOECHST AG
摘要:The invention relates to compounds of the formula Iin which the radicals R1, R2, R3 and A have the meaning mentioned in the description. The invention further relates to a process for the preparation of the compounds of the formula I by means of solid-phase synthesis, and use thereof as pharmaceuticals.

专利号:CN-117700459-B
优先权日:2023-12-25
标题 :Synthesis and application of a type of benzo five-membered C-P ring skeleton monophosphine ligand

专利号:CN-117700459-A
优先权日:2023-12-25
标 题:Synthesis method and application of a type of benzo five-membered C-P ring skeleton monophosphine ligand

专利号:CN-108864733-A
优先权日:2018-05-17
标 题 :A kind of near-infrared carborhodamine fluorescent dye and its synthesis method