CAS: 15450-76-7; 2,8-Dihydroxyquinoline

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CAS号15450-72-3 2-氧代-1,2-二氢喹啉-8... | CAS号148-24-3 8-羟基喹啉 | CAS号84-88-8 8-羟基-5-喹啉磺酸 | CAS号1127-45-3 8-羟基喹啉氮氧化合物 | CAS号52749-50-5 8-羟基-3,4-二氢-2(1... | CAS号93609-84-8 5-乙酰基-8-(苯甲氧基)-2-喹啉酮 | CAS号214349-09-4 8-methoxyquinol... | CAS号22614-69-3 8-甲氧基喹啉-2-酮 | CAS号74668-74-9 2-氯-8-甲氧基喹啉 | CAS号62978-73-8 5-乙酰基-2,8-二羟基喹啉 | CAS号15450-73-4 2,5,8(1H)-Quino... | CAS号15450-72-3 2-氧代-1,2-二氢喹啉-8... | CAS号31568-91-9 2-氯-8-羟基喹啉 | CAS号112281-28-4 5-(2-Oxiranyl)-...

3,4-二甲氧基肉桂酰氯置于aluminum (III) Chloride,三(五氟苯基)硼烷,三乙胺体系中,用 四氢呋喃 用作溶剂,化学反应 6.0H,反应生成2,8-喹啉二醇
参考文献:一种制备羟基-2(1H)-喹啉酮的方法
标题:一种制备羟基-2(1H)-喹啉酮的方法
摘要:本发明公开了一种制备羟基‑2(1H)‑喹啉酮的方法,属于有机化学领域.以氨基苯硼酸化合物和反式‑β‑芳基丙烯酰氯,在三乙胺或吡啶存在下反应生成反式酰胺中间体,然后在有机溶剂中,在无水三氯化铝和b(C6F5)3存在下,升温反应.反应结束降温,加入双氧水氧化后得到羟基‑2(1H)‑喹啉酮.该方法具有原料易得,通过不同的起始原料可以得到不同位置的羟基喹啉酮产物,丰富了现有的合成路线.

专利信息

专利号:US-5436143-A
优先权日:1992-12-23
标题:Method for enzymatic synthesis of oligonucleotides
发明人：HYMAN EDWARD D
摘要:Enzymatic synthesis of oligonucleotides may be performed in a single vessel without intermediate purification, by the steps of: n (a) combining a nucleotide primer sequence and a blocked nucleotide in the presence of a chain extending enzyme whereby a reaction mixture is formed containing the blocked nucleotide coupled to the nucleotide primer sequence at its 3' end; n (b) inactivating the chain extending enzyme; n (c) removing the blocking group from the primer-blocked nucleotide to form a primer-nucleotide product; and converting any unreacted blocked nucleotide to an unreactive form which is substantially less active as a substrate for the chain extending enzyme than the blocked nucleotide.

专利号:WO-2017178716-A1
优先权日:2016-04-14
标题 :Method for the synthesis of a mineral oxide using an organic acid insoluble in water
发明人：PARMENTIER FRANÇOIS
权利人:PARMENTIER FRANÇOIS
摘要:The invention relates to a method for the synthesis of precipitated silica from an aqueous solution comprising a silicate ion and an alkaline cation, said method being characterized in that the silicate ion is precipitated by a low-volatility organic acid having more than four carbon atoms.

专利号:US-4171439-A
优先权日:1975-04-11
标 题 :Antibacterial analogs of isocephalosporins
发明人：CONWAY TERRY T; LIM GARY M F; MENARD MARCEL
权利人:BRISTOL MYERS CO
摘要:There is described the stereoselective total synthesis of novel DELTA 2,3-1,4-morpholine-2-carboxylic acids possessing a fused beta -lactam ring in the 1,6-position and carrying a substituent cis to carbon 5 in the 7-position of the fused ring system represented by the general formula I wherein Z is halo or hydroxyl and X is acylamino. Also included in the invention are compounds of the above formula in which the carboxyl group at the 2-position is protected as by an easily cleavable ester group and salts of both the free acids and carboxyl-protected compounds. The compounds are potent antibacterial agents.

专利号:US-4112230-A
优先权日:1975-04-11
标题 :Δ2,3 -1,4 Morpholine-2-carboxylic acid derivatives as antibacterial agents
发明人：MENARD MARCEL; LIM GARY M F; CONWAY TERRY T
权利人:BRISTOL MYERS CO
摘要:There is described the stereoselective total synthesis of novel DELTA 2,3-1,4-morpholine-2-carboxylic acids possessing a fused beta -lactam ring in the 1,6-position and carrying a substituent cis to carbon 5 in the 7-position of the fused ring system represented by the general formula I wherein Z is halo, hydroxyl, etherified hydroxyl or hydroxyl esterified with a carboxylic acid residue or a sulfonic acid residue and X is amino, azido or acylamino. Also included in the invention are compounds of formula I in which the carboxyl group at the 2-position is protected as by an easily cleavable ester group and salts of both the free acids and carboxyl-protected compounds of formula I. The compounds of formula I are potent antibacterial agents or are of use as intermediates in the preparation of such antibacterial agents.

专利号:US-4166906-A
优先权日:1975-04-11
标题:0-2-Isocephem-4-carboxylic acid derivatives as antibacterial agents
发明人：CONWAY TERRY T; LIM GARY M F; MENARD MARCEL
权利人:BRISTOL MYERS CO
摘要:There is described the stereoselective total synthesis of novel DELTA 2,3-1,4-morpholine-2-carboxylic acids possessing a fused beta -lactam ring in the 1,6-position and carrying a substituent cis to carbon 5 in the 7-position of the fused ring system represented by the general formula I wherein Z is hydroxyl esterified with a sulfonic acid residue and X is acylamino. Also included in the invention are compounds of the above formula in which the carboxyl group of the 2-position is protected as by an easily cleavable ester group and salts of both the free acids and carboxyl-protected compounds. The compounds are potent antibacterial agents.

专利号:US-4166905-A
优先权日:1975-04-11
标题 :O-2-Isocephem-4-carboxylic acid derivatives as antibacterial agents
发明人：CONWAY TERRY T; LIM GARY M F; MENARD MARCEL
权利人:BRISTOL MYERS CO
摘要:There is described the stereoselective total synthesis of novel DELTA 2,3-1,4-morpholine-2-carboxylic acids possessing a fused beta -lactam ring in the 1,6-position and carrying a substituent cis to carbon 5 in the 7-position of the fused ring system represented by the general formula I wherein Z is etherified hydroxyl and X is acylamino. Also included in the invention are compounds of the above formula in which the carboxyl group at the 2-position is protected as by an easily cleavable ester group and salts of both the free acids and carboxyl-protected compounds. The compounds are potent antibacterial agents.