CAS: 13081-18-0; Ethyl 3,3,3-Trifluoro-2-Oxopropanoate

相似化合物

431-72-1 13089-11-7 94726-00-8

上下游产品

ethanol α,α-dihydroxytrifluoropropionic acid 2-fluoro-2-ethoxy-trifluoropropionic acid ethyl ester Hexafluoropropene oxide3,3,3-Trifluoro-N,N-dimethyl-2-oxo-propionamide ethyl 2-(((benzyloxy)carbonyl)amino)-3,3,3-trifluoro-2-hydroxypropanoate 5,7λ5-diphosphatricyclo2,6>decane-4,9-dicarboxylatediethyl 5,10-dioxo-2,2,7,7-tetraphenoxy-4,9-bis(trifluoromethyl)-3,8-dioxa-1,6-diaza-2λ5,7λ5-diphosphatricyclo5.3.0.02,6decane-4,9-dicarboxylate hept-4-ene3,6-Bis(ethoxycarbonyl)-1,1-dimethoxy-4-phenyl-3,6-bis(trifluoromethyl)-2,7-dioxa-1-phosphabicyclo3.2.0hept-4-ene

2-乙氧基-2,3,3,3-四氟-丙酸乙酯置于sbf5体系中,用83%的收率获得3,3,3-三氟丙酮酸乙酯
参考文献:Preparation Of Fluorocarbonyl Compounds
标题:Preparation Of Fluorocarbonyl Compounds
摘要:氟化羰基化合物是通过将含有至少一个甲氧基化碳原子含基团的氟化甲基或乙基醚与选择自--Cf.Sub.2 Or.Sup.3,.Dbd.Cfor.Sup.3,##str1## 其中r.Sup.3为ch.Sub.3或c.Sub.2 H.Sub.5的接触,与选择自sbx.Sub.5,Tax.Sub.5,Nbx.Sub.5,Asx.Sub.5,Bix.Sub.5,Tix.Sub.4,Zrx.Sub.4,Hfx.Sub.4,Fex.Sub.3,Sbx.Sub.3和sbx.Sub.5的混合物,Zm'X'.Sub.6以及zm'X'.Sub.6和m'X.Sub.5的混合物的催化剂反应,其中x独立地为f,Cl,Br或i,X'为f或cl;Z为h,No,O.Sub.2,碱金属或ny.Sub.4,其中y独立地为1至6个碳原子的h或烷基,M'为sb或as,温度为-20oc至200oc制备的.

专利信息

专利号:US-2006167025-A1
优先权日:2004-12-22
标 题:Tricyclic amino alcohols, processes for synthesis of same and use of same as anti-inflammatory drugs
发明人：BERGER MARKUS; SCHMEES NORBERT; SCHAECKE HEIKE; BAURLE STEFAN; REHWINKEL HARTMUT; MENGEL ANNE; KROLIKIEWICZ KONRAD; GROSSBACH DANJA; VOIGTLAENDER DAVID
权利人:BERGER MARKUS; SCHMEES NORBERT; SCHAECKE HEIKE; BAURLE STEFAN; REHWINKEL HARTMUT; MENGEL ANNE; KROLIKIEWICZ KONRAD; GROSSBACH DANJA; VOIGTLAENDER DAVID
摘要:The invention relates to tricyclic amino alcohols of general formula (I) n nmethod for synthesis of same and use of same as anti-inflammatory agents.

专利号:US-9440991-B2
优先权日:2013-12-23
标 题:Synthesis of an antiviral compound
发明人：CAGULADA AMY; CHAN JOHANN; CHAN LINA; COLBY DENISE A; KARKI KAPIL KUMAR; KATO DARRYL; KEATON KATIE ANN; KONDAPALLY SUDHA; LEVINS CHRIS; LITTKE ADAM; MARTINEZ RUBEN; PCION DOMINIKA; REYNOLDS TROY; ROSS BRUCE; SANGI MICHAEL; SCHRIER ADAM J; SENG PAMELA; SIEGEL DUSTIN; SHAPIRO NATHAN; TANG DONALD; TAYLOR JAMES G; TRIPP JONATHAN; WALTMAN ANDREW W; YU LAWRENCE
权利人:GILEAD SCIENCES INC
摘要:The present disclosure provides processes for the preparation of a compound of formula I: n nwhich is useful as an antiviral agent. The disclosure also provides compounds and processes for the preparation of the compounds that are synthetic intermediates to the compound of formula I.

专利号:US-2022363662-A1
优先权日:2021-04-20
标题 :Compounds as lxr agonists
发明人：PUJALA BRAHMAM; SATHE BALAJI DASHRATH; DANODIA ABHINANDAN; GUPTA ASHU; SONI SANJEEV; KUMAR VIVEK; ANSARI AMANTULLAH; KHAN FARHA; SARKAR ARINDAM; PAYGHAN PAVAN V
权利人:INTEGRAL BIOSCIENCES PRIVATED LTD
摘要:The present invention generally discloses compounds having LXR (the liver X receptor) agonistic activity, to the use of such compounds in the treatment of various disorders such as proliferative disorders, Alzheimer's disease, inflammatory diseases, and diseases characterized by defects in cholesterol and lipid metabolism. Specifically, the present invention discloses compound of formula (IA) which exhibit LXR agonist activity, specifically to LXRβ. The invention also discloses method of synthesis of said compounds, method of using said compounds, pharmaceutical compositions comprising said compounds and method of using thereof.

专利号:US-2017210756-A1
优先权日:2013-12-23
标题 :Synthesis of an antiviral compound

专利号:CN-110526848-B
优先权日:2019-09-04
标 题:Synthesis of β-Substituted Pyrrolidines by Intermolecular Hydrogen Transfer Induced Cyclic Amine β-C(sp3)–H Functionalization

专利号:WO-0053313-A2
优先权日:1999-03-09
标 题:Lanthanide catalysts for synthesis of compounds and combinatorial libraries