CAS: 103935-47-3; 2-Bromoethyl Trifluoromethanesulfonate

该化合物是有机化合物,其结构特征包括一个溴原子和一个附于乙基链的三叶酸(OSO2CF3),该化合物一般没有色素,可粉黄液体,因其反应性而闻名,特别是因其三叶酸盐离子组的存在而引发的核生殖性替代反应,该组被认为是有机化学中最佳的离子组之一;溴原子还有助于其电子生物特性,使其在各种合成应用中有用,包括形成碳-碳联结和引入功能组.2-溴乙基三氟酸酯通常用于制药和材料化学中较复杂的分子合成,但应谨慎处理,因为其潜在毒性和再活性,在使用时必须采取适当的安全防范措施.

结构式图片

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CAS号358-23-6 三氟甲磺酸酐 | CAS号540-51-2 2-溴乙醇 | CAS号108-48-5 2,6-二甲基吡啶 | CAS号141072-57-3 hydroxyethyl bromide | CAS号54509-73-8 ethene | CAS号35895-70-6 四丁基三氟甲磺酸铵 | CAS号33454-82-9 三氟甲磺酸锂 | CAS号2923-28-6 三氟甲烷磺酸银 | CAS号106-93-4 1,2-二溴乙烷 | CAS号106114-43-6 8-[4-(4-fluorop... | CAS号106114-42-5 3-N-(2-fluoroet... | CAS号762-49-2 1-溴-2-氟乙烷

合成工艺路线路线简述

    📜2,6-二甲基吡啶,1-Bromoethanol置于trifluoromethanesulfonic Acid Anhydride体系中,用 二氯甲烷 用作溶剂,以72%的收率获得三氟甲磺酸2-溴-乙酯
    参考文献:Chelating Compounds,Their Complexes With Paramagnetic Metals
    标题:Chelating Compounds,Their Complexes With Paramagnetic Metals
    摘要:能够螯合双价和三价顺磁性金属离子的化合物,所述金属离子的螯合配合物以及生理上相容的盐,以及它们在"磁共振成像"(M.R.I.)技术中作为对比剂的使用.

    专利信息


    专利号:US-7517895-B2
    优先权日:2001-08-24
    标题 :Synthetic diazonamides
    发明人:HARRAN PATRICK G; LI JING; JEONG SUSAN
    权利人:UNIV TEXAS
    摘要:The application discloses novel synthetic compounds, modeled after unique toxins extracted from the marine invertebrate Diazona angulata useful in the treatment abnormal cell mitosis. The application also discloses novel methods for synthesis of these compounds and methods of using these compounds.

    专利号:US-8071785-B2
    优先权日:2006-06-09
    标题:Synthesis and evaluation of 18F-labelled-alkyl-1-[(1R)-1-phenylethyl]-1H-imidazole-5-carboxylate as a tracer for the quantification of β-11-hydroxylase enzyme in the adrenal glands
    发明人:LANGSTROM BENGT; KARIMI FARHAD; BLOM ELISABETH; ERLANDSSON MARIA
    权利人:LANGSTROM BENGT; KARIMI FARHAD; BLOM ELISABETH; ERLANDSSON MARIA; GE HEALTHCARE LTD
    摘要:Radioactively labeled derivatives of (R)-3-(1-phenylethyl)-3H-imidazole-4-carboxylic acid esters and one-step methods for preparing these compounds are provided. The radioactively labelled compounds, and pharmaceutical acceptable salts and solvates are useful as radiopharmaceuticals, especially for use in Positron Emission Tomography (PET) for the diagnosis of adrenal cortical masses such as incidentaloma, adenoma, primary and metastatic cortical carcinoma. Associated kits and method for PET studies are also provided.

    专利号:US-7754188-B2
    优先权日:2003-06-30
    标 题:Radiolabeled cannabinoid-1 receptor modulators
    发明人:BURNS H DONALD; CHEN ALEX M; GIBSON RAYMOND E; GOULET MARK T; HAGMANN WILLIAM K; HAMILL TERENCE G; JEWELL JAMES P; LIN LINUS S; LIU PING; PERESYPKIN ANDREY V
    权利人:MERCK SHARP & DOHME
    摘要:The present invention relates to particular radiolabeled Cannabinoid-1 (CB1) receptor modulators, and methods of using these modulators for labeling and diagnostic imaging of Cannabinoid-1 receptors in mammals, particularly humans. In addition, intermediates useful for the synthesis of the radiolabeled Cannabinoid-1 receptor modulators are also disclosed, as well as the processes for synthesizing the radiolabeled Cannabinoid-1 receptor modulators. Still further, formulations of the radiolabeled Cannabinoid-1 receptor compounds are described.

    专利号:US-7022720-B2
    优先权日:2001-08-24
    标 题 :Synthetic diazonamides as novel anti-mitotic agents
    发明人:HARRAN PATRICK G; LI JING; JEONG SUSAN
    权利人:UNIV TEXAS
    摘要:The application discloses novel synthetic compounds, modeled after unique toxins extracted from the marine invertebrate Diazona angulata useful in the treatment abnormal cell mitosis. The application also discloses novel methods for synthesis of these compounds and methods of using these compounds.

    专利号:US-2009297447-A1
    优先权日:2006-06-09
    标 题 :Synthesis and evaluation of 18f-labelled-alkyl-1-[(1r)-1-phenylethyl]-1h-imidazole-5-carboxylate as a tracer for the quantification of beta-11-hydroxylase enzyme in the adrenal glands

    专利号:WO-2007144725-A2
    优先权日:2006-06-09
    标 题:SYNTHESIS AND EVALUATION OF 18F-LABELLED ALKYL-1-[(R)-1-PHENYLETHYL]-1H-IMIDAZOLE-5-CARBOXYLATE AS A TRACER FOR THE QUANTIFICATION OF β-11-HYDROXYLASE ENZYME IN THE ADRENAL GLANDS

    供应商参考报价(招募中)

    品牌试剂参考报价(招募中)

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    合成参考文献


    摘要:Drabowicz, J.; Kiełbasiński, P.; Mikołajczyk, M., Science of Synthesis, (2007) 33, 169.
    摘要:Tang, Y.; Sun, X.-L., Science of Synthesis, (2008) 39, 853.
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