CAS: 84-88-8; 8-Hydroxyquinoline-5-Sulfonic Acid

该化合物是一种有机化合物,其特点是一种由氢氧化物组和磺酸组替代的quinoline结构,其典型特征是,由于在quinline环中存在氢氧化物和氮功能,该化合物能够起到发泡剂的作用,特别是金属离子的作用,因此,该化合物具有典型的特点是具有作为发泡剂的作用,特别是金属离子;该化合物经常用于分析化学,用于检测和量化各种金属离子,因为它构成稳定的复合物;该盐酸组增强了其在水中的溶性,使其适合各种水中的应用;此外,8-氢氧基氨基碱-5-硫酸的外溢光性能在某些分析技术中可能具有优势;必须小心处理该化合物,因为如果浸入或吸入,可能会对健康造成危害;实验室使用时,应采取适当的安全措施.

结构式图片

相似化合物

283158-18-9 29021-67-8 547-91-1

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上下游产品

8-quinolinol 8-chloro-quinoline-5-sulfonic acid 1,2-di[(Ξ)-phthalidyliden]-ethane sodium methylate quinoline-2,8-diol Pyridine-2,3-dicarboxylic acid 8-aminoquinoline-5-sulphonic acid 8-hydroxy-7-iodo-quinoline-5-sulfonic acid

合成工艺路线路线简述

  • 148-24-3 = 84-88-8
    反应条件:1.1 Reagents: Fuming Sulfuric Acid; Overnight,Rt
    标题:New Trick For An Old Ligand! The Sensing Of Zn(Ii) Using A Lanthanide Based Ternary Yb(Iii)-Cyclen-8-Hydroxyquinoline System As A Dual Emissive Probe For Displacement Assay
    作者:Comby,Steve; Tuck,Sarah A.; Truman,Laura K.; Kotova,Oxana; Gunnlaugsson,Thorfinnur
    参考文献:Inorganic Chemistry 日期:2012 卷标:51(19) 页码:10158-10168]

    148-24-3 = 84-88-8
    反应条件:1.1 Reagents: Sulfur Trioxide,Sulfuric Acid
    标题:Synthesis Of 7-(2-Carboxy-4-Bromobenzeneazo)-8-Hydroxyquinoline-5-Sulfonic Acid And Spectrophotometric Determination Of Molybdenum In Foods
    作者:Yu,Ying; Peng,Shanshan; Huang,Jianfeng
    参考文献:Huaxue Shiji 日期:1992 卷标:14(6) 页码:337-9]

    98-37-3 = 84-88-8
    反应条件:1.1 Reagents: Hydrochloric Acid Solvents: Water; 1 H,Reflux1.2 Reagents: Sodium Bicarbonate Solvents: Water; Neutralized,Rt1.3 Reagents: Hydrochloric Acid Solvents: Water; Ph 4,Rt
    标题:Development Of New Cathepsin B Inhibitors: Combining Bioisosteric Replacements And Structure-Based Design To Explore The Structure-Activity Relationships Of Nitroxoline Derivatives
    作者:Sosic,Izidor; Mirkovic,Bojana; Arenz,Katharina; Stefane,Bogdan; Kos,Janko; Et Al
    参考文献:Journal Of Medicinal Chemistry 日期:2013 卷标:56(2) 页码:521-533]

    148-24-3 + 302-17-0 = 84-88-8 + 23218-68-0
    反应条件:1.1 Reagents: Sulfuric Acid Solvents: Water; Rt; Rt -> 80 °C; 12 H,80 °C1.2 Reagents: Water; Cooled
    标题:Study On The Process Of Joint Production Of 8-Hydroxyquinoline-5-Carbaldehyde And 8-Hydroxyquinoline-5-Sulphonic Acid
    作者:Qi,Jiajuan; Li,Shuan; Zhang,Zhenming; Wang,Ting; Zhao,Hongbo
    参考文献:Huagong Shikan 日期:2013 卷标:27(10) 页码:1-5
8-羟基喹啉置于硫酸体系中,化学反应 30.0H,反应生成 8-羟基喹啉-5-磺酸水合物
参考文献:取代8-羟基喹啉锌配合物的荧光性质与结构关系的研究.
标题:取代8-羟基喹啉锌配合物的荧光性质与结构关系的研究.
摘要:由8-羟基喹啉金属络合物生产的有机发光二极管(oled)在现代电致发光器件中起着至关重要的作用.本文采用不同的方法合成了一系列的8-羟基喹啉衍生物,并制备了相应的锌金属配合物.测量了配合物的紫外和荧光性质,旨在了解喹啉环上的取代基对配合物的荧光性质的影响.当8-羟基喹啉的c-5被卤素取代时,荧光发射波长发生了红移,同时,当8-羟基喹啉的c-5位置为2时,观测到荧光发射波长发生了蓝移.被吸电子基团取代.
DOI:10.1007/s10895-018-2275-7

海关参考信息

专利信息


专利号:US-8735586-B2
优先权日:2007-06-26
标 题 :Regioselective copper catalyzed synthesis of benzimidazoles and azabenzimidazoles
发明人:ALONSO JORGE; LINDENSCHMIDT ANDREAS; NAZARÉ MARC; URMANN MATTHIAS; HALLAND NIS; RKYEK OMAR
权利人:ALONSO JORGE; LINDENSCHMIDT ANDREAS; NAZARÉ MARC; URMANN MATTHIAS; HALLAND NIS; RKYEK OMAR; SANOFI SA
摘要:The present invention relates to a process for the regioselective synthesis of compounds of the formula I, n nwherein R0; R1; R2; R3; R4; R5; A1; A2; A3; A4, Q and J have the meanings indicated in the claims. The present invention provides a direct copper catalyzed regioselective process to a wide variety of unsymmetrical, multifunctional N-substituted benzimidazoles or azabenzimidazoles of formula I starting from 2-halo-nitroarenes and N-substituted amides.

专利号:EP-2173747-B1
优先权日:2007-06-26
标 题:A regioselective metal catalyzed synthesis of annelated benzimidazoles and azabenzimidazoles
发明人:ALONSO JORGE; LINDENSCHMIDT ANDREAS; NAZARE MARC; R KYEN OMAR; URMANN MATHIAS; HALLAND NIS
权利人:SANOFI SA
摘要:The present invention relates to a process for the regioselective synthesis of compounds of the formula I, wherein R1; R2; R3; R4; J1; J2; J3; J4 and G have the meanings indicated in the claims. The present invention provides a direct metal, e.g. palladium or copper, catalyzed, regioselective process to a wide variety of unsymmetrical, multifunctional N-substituted benzimidazoles or azabenzimidazoles of formula I starting from 2-halo-nitroarenes and N-substituted amides.

专利号:US-7105617-B2
优先权日:2003-02-06
标题:Metal 8-hydroxyquinoline-functionalized polymers and related materials and methods of making and using the same
发明人:WECK MARCUS; MEYERS AMY
权利人:GEORGIA TECH RES INST
摘要:This invention relates to the synthesis of Mq n -containing monomeric compounds, comprising a polymerizable moiety, an Mq n -moiety, and an optional chemical spacer therebetween, wherein q, in each instance, comprises an 8-hydroxyquinoline residue, M is a metal such as Mg, Zn, Al, Ga, or In, and n is 2 or 3 as the valence of the metal requires. For example, the polymerization of Znq 2 - or Alq 3 -containing monomers, in the presence or absence of a co-monomer, provided a Znq 2 - or Alq 3 -containing polymer, which retained the optical properties of Znq 2 or Alq 3 in solution, respectively. The Mq n -containing polymers may be used in, among other things, the fabrication of light-emitting diodes (LEDs).

专利号:US-4707500-A
优先权日:1979-11-07
标 题:Synthetic crystalline ferroborosilicate compositions, the preparation thereof and their use in the conversion of synthesis gas to low molecular weight hydrocarbons
发明人:HINNENKAMP JAMES A; WALATKA VERNON V
权利人:NAT DISTILLERS CHEM CORP
摘要:Crystalline ferroborosilicate compositions are prepared from a silica containing mixture by digesting a reaction mixture comprising a tetraalkylammonium compound, a sodium hydroxide, a boron compound, an oxide of silicon, an iron ion source, an optional chelating agent and water to provide the crystalline ferroborosilicate which is then palladium ion-exchanged. This composition may be used alone or physically mixed with a methanol catalyst. Conversion of synthesis gas, dimethylether, ethylene and methanol to low molecular hydrocarbons employing these new ferroborosilicates as catalysts is also disclosed.

专利号:US-4670474-A
优先权日:1981-04-22
标 题:Synthetic crystalline metallosilicate compositions, the preparation thereof and their use in the conversion of synthesis gas to low molecular weight hydrocarbons
发明人:HINNENKAMP JAMES A; WALATKA VERNON V
权利人:NAT DISTILLERS CHEM CORP
摘要:Crystalline palladium or platinum ferrometallosilicate compositions are prepared from a silica-containing mixture by digesting a reaction mixture comprising (a) a tetraalkylammonium compound, (b) a sodium hydroxide, (c) a titanium compound, an aluminum compound, or a manganese compound, (d) an oxide of silicon, (e) an iron ion source, (f) optionally, a chelating agent and (g) water to provide a crystalline ferrometallosilicate which is then palladium or platinum ion-exchanged. Conversion of synthesis gas to low molecular hydrocarbons with high C 2 -C 3 alkanes selectivity employing these new ferrometallosilicates as catalysts is also disclosed.

专利号:US-2010261909-A1
优先权日:2007-06-26
标题 :Regioselective copper catalyzed synthesis of benzimidazoles and azabenzimidazoles
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主要参考文献

[参考文献]: A S Yanni, Et Al. Synthesis And Biological Activity Of Some 5-Substituted Aminomethyl-8-Hydroxyquinoline-7-Sulphonic Acids. J Chem Technol Biotechnol. 1990;49(3):243-7.
[参考文献]: Ana Isabel Martínez-Gómez, Et Al. Potential Application Of N-Carbamoyl-Beta-Alanine Amidohydrolase From Agrobacterium Tumefaciens C58 For Beta-Amino Acid Production. Appl Environ Microbiol. 2009 Jan;75(2):514-20.
[参考文献]: éva A Enyedy, Et Al. Comparative Solution Equilibrium Studies Of Anticancer Gallium(Iii) Complexes Of 8-Hydroxyquinoline And Hydroxy(Thio)Pyrone Ligands. J Inorg Biochem. 2012 Dec:117:189-97.
[参考文献]: K A Mookhtiar, Et Al. Functional Constituents Of The Active Site Of Human Neutrophil Collagenase. Arch Biochem Biophys. 1986 May 1;246(2):645-9.
[参考文献]: M Kodová, Et Al. Self-Assembled Polymeric Chelate Nanoparticles As Potential Theranostic Agents. Chemphyschem. 2012 Dec 21;13(18):4244-50.

合成参考文献


摘要:S10 | SWISSPHARMA | Pharmaceutical List with Consumption Data | DOI:10.5281/zenodo.2623484
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