CAS: 76-44-8; Heptachlor

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CAS号3734-48-3 六氯 | CAS号542-92-7 环戊二烯 | CAS号77-47-4 六氯环戊二烯

📜1-羟基氯丹 反应生成 七氯
参考文献:Kleemeyer,H.;Thiemann,W.,Chemosphere,1986,15,N 6,687-692
标题:Kleemeyer,H.;Thiemann,W.,Chemosphere,1986,15,N 6,687-692

专利信息

专利号:US-5872245-A
优先权日:1992-09-30
标题 :Continuous process for the synthesis of sucrose fatty acid esters
发明人：WILSON DONALD C
权利人:OPTIMA TECHNOLOGIES GROUP
摘要:This present invention pertains to a process for the synthesis of sucrose fatty acid esters by reacting sucrose and a purified specific fatty acid ester under substantially solvent free conditions in the presence of a transesterification stationary catalyst and mechanical emulsification. The process is continuous, yielding selected individual products of separated simple sucrose fatty acid esters of mono-, di-, tri- and polyesters while recycling the unwanted ester fractions, the unreacted sucrose and fatty acid ester.

专利号:US-8816117-B2
优先权日:2009-09-01
标 题 :Synthesis of fluorocarbofunctional silsesquioxanes
发明人：MARCINIEC BOGDAN; MACIEJEWSKI HIERONIM; DUTKIEWICZ MICHAL
权利人:MARCINIEC BOGDAN; MACIEJEWSKI HIERONIM; DUTKIEWICZ MICHAL; UNIV ADAM MICKIEWICZ
摘要:The subject of the invention is the method of synthesis of fluoracarbofunctional cage silsesquioxanes of the general formula in which•R 1 stands for HCF 2 (CF 2 ) n (CH 2 )mO(CH 2 ) 3 Si(CH 3 ) 2 O or HCF 2 (CF 2 ) n (CH 2 ) m O(CH 2 ) 3 group in which n=1-12, m=1-4;•R 2 , R 3 , R 4 , R 5 , R 6 , R 7 , R 8 can be the same as R 1 or different from it and stand all either for the (C 1 -C 25 ) alkyl group or any aryl group, based on hydrosilylation of fluoroalkyl-allyl ether with an appropriate hydrogen-silsesquioxane in the presence of siloxide rhodium complex [{Rh(OSiMe 3 )(cod)} 2 ] as a catalyst.

专利号:US-6887887-B2
优先权日:2001-03-19
标 题:Asymmetric synthesis of (S,S,R)-(-)-actinonin and its analogs and uses therefor
发明人：BORNMANN WILLIAM G; SIROTNAK FRANCIS; SCHER HOWARD; VIDAL EPHRAIM; BORELLA CHRISTOPHER; SCHEINBERG DAVID
权利人:SLOAN KETTERING INST CANCER
摘要:The present invention provides methods for the asymmetric synthesis of (S,S,R)-(−)-actinonin and its analogs and the compounds thereby synthesized having a structural formula: n n nwhere R 1 is an optionally substituted or halogenated alkyl, aryl, heteroalkyl or heteroaryl amine, said R 1 further comprising a cyclic or bicyclic structure; R 2 is methyl, CH 2 CH 3 , (CH 2 ) 2 CH 3 , C(CH 3 ) 3 , phenyl, 3,4-dichlorophenyl, biphenyl, benzyl, 4-hydroxybenzyl, piperidine, N-Boc-4-piperidine, CH 2 -(N-Boc-4-piperidine), 4-tetrahydropyran, CH 2 -4-tetrahydropyran, 3-methyl indolyl, 2-naphthyl, 3-pyridyl, 4-pyridyl, 3-thienyl; R 3 is R 2 or C 3-8 alkyl, R 4 is C 1-3 alkyl; and R 5 is NH 2 , OH, NHOH, NHOCH 3 , N(CH 3 )OH, N(CH 3 )OCH 3 , NHCH 2 CH 3 , NH(CH 2 CH 3 ), NHCH 2 (2,4-(OCH3) 2 Ph, NHCH 2 (4-NO 2 )Ph, NHN(CH 3 ) 2 , proline, or 2-hydroxymethyl pyrrolidine. Additionally, a method for the treatment of a neoplastic disease or for the inhibition of tumor cell growth each comprising the step of administering to an individual in need of such treatment a pharmacologically effective dose of the compounds of the present invention are provided.

专利号:WO-9420521-A1
优先权日:1993-03-12
标 题:Process for synthesizing and selecting sequences of covalently bound components
发明人：SCHNEIDER-MERGENER JENS
权利人:SCHERING AG; SCHNEIDER MERGENER JENS
摘要:A process is disclosed for the solid phase or liquid phase synthesis of selectable sequences of aminoacids of monosaccharides, the coupling sites being predetermined on a substrate. The sequences consist of determined aminoacids or monosaccharides and of undetermined aminoacids or monosaccharides at a defined position in the sequence. According to the process the synthesis of the sequence is carried out in a continuous way and comprises, the following steps: (aa) adding the determined aminoacid or the determined monosaccharide at a defined site on the substrate, and (bb) adding to the substrate a mixture of undetermined aminoacids or monosaccharides equimolar with regard to the coupling sites.

专利号:US-8173770-B2
优先权日:2001-12-29
标 题 :Intermediates for LHRH antagonist synthesis, process for the production, and process for LHRH antagonist production
发明人：RASMUSSEN JON H; RASMUSSEN PALLE H; WACHS WOLFGANG O; HANSEN STEFAN; FOMSGAARD JENS
权利人:RASMUSSEN JON H; RASMUSSEN PALLE H; WACHS WOLFGANG O; HANSEN STEFAN; FOMSGAARD JENS; CARLBIOTECH LTD AS
摘要:The peptides Ac-D-2Nal-D-4ClPhe-D-3Pal-OH and Boc-D-2Nal-D-4ClPhe-D-3Pal-OH are intermediates useful in the synthesis of LHRH analogs by coupling with suitable heptapeptides, in particular with the heptapeptides P 1 -Ser(P 2 )-MMeTry(P 3 )-D-Lys(Nic)-Leu-Lys(iPr,P 4 )-Pro-D-AlaNH 2 and P 1 -Ser(P 2 )-NMeTry(P 3 )-D-Asn-Leu-Lys(iPr,P 4 )-Pro-D-AlaNH 2 .

专利号:US-6121440-A
优先权日:1998-01-29
标 题 :Process for synthesis of polyol fatty acid polyesters
发明人：KENNEALLY COREY JAMES; BUSCH GARY ALLEN; CORRIGAN PATRICK JOSEPH; GRANBERG ERIC PAUL; HOWIE JOHN KEENEY; SCHAFERMEYER RICHARD GERARD; TROUT JAMES EARL
权利人:PROCTER & GAMBLE
摘要:A process for preparing esterified polyol fatty acid polyesters is provided, where the polyol has n hydroxyl groups. The process provides for independent control of the level of fully esterified polyols, on the one hand, and the level of n-3 and lower esters, on the other hand. The process is especially suited for preparing sucrose polyester, wherein the process provides for independent control of the level of octaesters, on the one hand, and penta and lower level esters, on the other hand. The process can be used to reduce the level of undesirable reaction byproducts, such as difatty ketone and beta ketoester.