CAS: 72571-06-3; 5-(4-Bromophenyl)Oxazole
该化合物是一种有机化合物,其特征是其氧化氮环,这是一个五人组成的含有氮和氧原子的环环环,由五人组成,由五人组成,由五人组成,由五人组成,含有氮和氧原子的环形体组成;一个溴联苯组存在于该氧化氮环形体的五处位置上,有助于其独特的化学特性,包括脂性增加和各种化学反应的可能性.这种化合物通常在标准条件下表现出中度至高度的稳定性,但其再活性可能受到溴基替代物的影响,而溴基体则可以参与电药用替代反应.此外,5-(4-Bromomobony)oxanole可能展示出有趣的生物活动,使其在医药化学和材料科学中引起兴趣,其溶剂的溶性特性可能因溶剂而不同,并可能用于其他化学实体的合成或有机合成的建筑块.
相似化合物
243455-57-4 1006-68-4 1008-94-2物理性质
MSDS等安全信息
欧盟法规
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- 合成目标产物 5-(4-Bromophenyl)-1,3-Oxazole 主要起始原料 4-Bromobenzaldehyde
- (文献来源)合成步骤主要原料 4-Bromobenzaldehyde
📜2-氨基-4-溴苯乙酮 盐酸盐置于盐酸,Sodium Hydroxide,三氯氧磷体系中,用 乙醇,水,甲苯,苯 作为反应溶剂,化学反应生成 5-(4-溴苯基)噁唑
参考文献:5-(4-Bromophenyl)Oxazole
标题:5-(4-Bromophenyl)Oxazole
摘要:化合物5-(4-溴苯基)噁唑可用作抗真菌剂.
专利信息
专利号:US-2010286211-A1
优先权日:2004-10-08
标题:Oxazolidinone derivatives as antimicrobials
发明人：DAS BISWAJIT; AHMED SHAHADAL; YADAV AJAY SINGH; GHOSH SOMA; GUJRATI ARTI; SHARMA PANKAJ; RATTAN ASHOK
权利人:DAS BISWAJIT; AHMED SHAHADAL; YADAV AJAY SINGH; GHOSH SOMA; GUJRATI ARTI; SHARMA PANKAJ; RATTAN ASHOK
摘要:The present invention relates to certain substituted phenyl oxazolidinones and to processes for the synthesis of the same. This invention also relates to pharmaceutical compositions containing the compounds of the present invention as antimicrobials. The compounds are useful antimicrobial agents, effective against a number of human and veterinary pathogens, including gram-positive aerobic bacteria, for example, multiple-resistant staphylococci, streptococci and enterococci as well as anaerobic organisms, for example, Bacterioides spp. and Clostridia spp. species, and acid fast organisms, for example, Mycobacterium tuberculosis, Mycobacterium avium and Mycobacterium spp.
专利号:ZA-202203820-B
优先权日:2022-04-04
标 题:A method for synthesis and evaluation of in vitro antitumor activity of novel 5-(4-bromophenyl)-1,3-oxazole derivatives
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📌 第三方产品分析报告
主要参考文献
参考标题: Oxazolidinone Derivatives As Antimicrobials Derives D'Oxazolidinone Utilises Comme Agents Antimicrobiens摘要:The Present Invention Relates To Certain Substituted Phenyl Oxazolidinones And To Processes For The Synthesis Of The Same. This Invention Also Relates To Pharmaceutical Compositions Containing The Compounds Of The Present Invention As Antimicrobials. The Compounds Are Useful Antimicrobial Agents, Effective Against A Number Of Human And Veterinary Pathogens, Including Gram-Positive Aerobic Bacteria, For Example, Multiple-Resistant Staphylococci, Streptococci And Enterococci As Well As Anaerobic Organisms, For Example, Bacterioides Spp. And Clostridia Spp. Species, And Acid Fast Organisms, For Example, Mycobacterium Tuberculosis, Mycobacterium Avium And Mycobacterium Spp.
合成参考文献
参考文献:10.1016/j.bbrc.2023.08.050
摘要:Ikeda Y, Davis MI, Sumita K, Zheng Y, Kofuji S, Sasaki M, Hirota Y, Pragani R, Shen M, Boxer MB, Takeuchi K, Senda T, Simeonov A, Sasaki AT. Multimodal action of KRP203 on phosphoinositide kinases in vitro and in cells. Biochemical and Biophysical Research Communications. 2023 Oct;679():116–21. doi: 10.1016/j.bbrc.2023.08.050.
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