专利号:US-2003187271-A1 优先权日:2002-03-27 标题 :Synthesis of 2, 6-dicarbonylpyridines
专利号:US-8609801-B2 优先权日:2011-09-29 标题:Polymers and copolymers containing 2H-benzimidazol-2-one moieties 发明人:HAY ALLAN S; MIR AABID; HLIL ANTISAR R; MATSUMURA SUMIKO 权利人:UNIV MCGILL; UNIV MCGILL 摘要:Polymers and copolymers containing 1H-benzo[d]imidazol-2(3H)-one units have been synthesized under conditions generally used for the synthesis of poly(aryl ether)s. 1H- n nbenzo[d]imidazol-2(3H)-one behaves like a biphenol in the polymerization reaction.n n The soluble homopolymer has a very high glass transition temperature (348° C.), good thermal stability, and forms flexible transparent films. Because of the low molecular weight (134.14) of the benzoimidazolone monomer in the copolymer formed with 4,4′-biphenol that contains 30 mole % of the benzimidazolone unit, only 8.9 weight % is required to raise the Tg of the poly(arlyl ether)sulfone from 220° C. to 269° C.
专利号:CN-101475460-A 优先权日:2009-01-16 标题 :Synthesis of curcumin analogues containing bis[3-(substituted phenyl)acryloyl]benzene
专利号:US-9000220-B2 优先权日:2009-08-31 标题 :Organophosphorus compounds based on tetraphenol (TP)-substituted structures 发明人:CHRISTIANSEN ANDREA; FRANKE ROBERT; FRIDAG DIRK; HESS DIETER; KREIDLER BURKARD; VOGT DIETER; BINI LAURA; JANSSEN MICHELE; HAMERS BART 权利人:CHRISTIANSEN ANDREA; FRANKE ROBERT; FRIDAG DIRK; HESS DIETER; KREIDLER BURKARD; VOGT DIETER; BINI LAURA; JANSSEN MICHELE; HAMERS BART; EVONIK DEGUSSA GMBH 摘要:The invention relates to the synthesis of tetraphenol-substituted structures, in particular meta-substituted xylenes. Said tetraphenol-type structures are reacted to obtain organic phosphorus compounds, in particular organophosphites. The invention further relates to the production of catalytically active compositions which contain transition metals in addition to the aforementioned organic phosphorus compounds. According to another subject matter of the invention, said catalytically active compositions are used in chemical reactions with small molecules, e.g. HCN, CO, hydrogen, and amines.
专利号:US-5491167-A 优先权日:1993-01-29 标题 :Hexahydronaphthalene ester derivatives, their preparation and their therapeutic uses 发明人:ISHIHARA SADAO; KOGEN HIROSHI; KOGA TEIICHIRO; KITAZAWA EIICHI; SERIZAWA NOBUFUSA 权利人:SANKYO CO 摘要:Compounds of formula (I): ##STR1## and their salts and esters have the ability to inhibit the synthesis of cholesterol, and can thus be used for the treatment and prophylaxis of hypercholesterolemia and of various cardiac disorders.
专利号:US-9334275-B2 优先权日:2011-12-19 标题:Processes for preparing indoles 发明人:YOSHIKAI NAOHIKO; WEI YE 权利人:UNIV NANYANG TECH 摘要:Methods for the synthesis of an indole in provided. Methods comprise oxidizing a N-aryl imine in the presence of a palladium-based catalyst, an oxidant, and a solvent.
[参考文献]: Min-Sun Kim, Et Al. Amino Acid And Protein Targets Of 1,2-Diacetylbenzene, A Potent Aromatic Gamma-Diketone That Induces Proximal Neurofilamentous Axonopathy. Toxicol Appl Pharmacol. 2002 Aug 15;183(1):55-65.
合成参考文献
摘要:Liu, S.; Xiao, J., Science of Synthesis: Cross Coupling and Heck-Type Reactions, (2012) 3, 217. 摘要:Liu, S.; Xiao, J., Science of Synthesis: Cross Coupling and Heck-Type Reactions, (2012) 3, 213. 摘要:OʼBrien, M.; Polyzos, A., Science of Synthesis: Flow Chemistry in Organic Synthesis, (2018) 1, 255.