CAS: 55896-93-0; Ethyl 2-(Chlorosulfonyl)Acetate

相似化合物

56146-83-9 69371-75-1 51517-01-2

上下游产品

CAS号89124-45-8 SULFO-ACETIC AC... | CAS号105-39-5 氯乙酸乙酯 | CAS号623-51-8 巯基乙酸乙酯 | CAS号64-17-5 乙醇 | CAS号4025-77-8 氯磺酰乙酰氯 | CAS号75680-93-2 6-氯-[1,2,4]三唑并[... | CAS号76195-97-6 ethyl 2-((2-(6-... | CAS号69579-06-2 ethyl 2-[(6-chl... | CAS号658709-20-7 ethyl 2-[(4-iod... | CAS号87712-30-9 ethyl 2-[methyl... | CAS号61154-54-9 ethyl 2-[benzyl... | CAS号61154-55-0 ethyl 2-[methyl... | CAS号61154-59-4 ethyl 2-[(2-nit... | CAS号61154-60-7 ethyl 2-[(5-chl... | CAS号61154-66-3 2-[(4-chloro-2-...

磺基-乙酸乙酯置于三氯氧磷体系中,用80%的收率获得产物(氯磺酰基)乙酸乙酯
参考文献:Sulfonate Acat Inhibitors
标题:Sulfonate Acat Inhibitors
摘要:β-羧基磺酸盐的结构式为##str1##其中r₁为芳基,R₃和r₄为氢或烷基,Y为-O-,-S-或-Nr₂-,R₅为烷基或芳基,是酰基辅酶a:胆固醇酰基转移酶(acat)的强效抑制剂,因此可用于治疗高胆固醇血症和动脉粥样硬化.

专利信息

专利号:US-8507538-B2
优先权日:2009-11-13
标 题:Selective heterocyclic sphingosine 1 phosphate receptor modulators
发明人：BOEHM MARCUS F; MARTINBOROUGH ESTHER; BRAHMACHARY ENUGURTHI; MOORJANI MANISHA; TAMIYA JUNKO; HUANG LIMING; YEAGER ADAM RICHARD
权利人:BOEHM MARCUS F; MARTINBOROUGH ESTHER; BRAHMACHARY ENUGURTHI; MOORJANI MANISHA; TAMIYA JUNKO; HUANG LIMING; YEAGER ADAM RICHARD; RECEPTOS INC
摘要:Compounds that selectively modulate the sphingosine 1 phosphate receptor are provided including compounds which modulate subtype 1 of the S1P receptor. Methods of chiral synthesis of such compounds is provided. Uses, methods of treatment or prevention and methods of preparing inventive compositions including inventive compounds are provided in connection with the treatment or prevention of diseases, malconditions, and disorders for which modulation of the sphingosine 1 phosphate receptor is medically indicated.

专利号:US-9481659-B2
优先权日:2011-05-13
标 题 :Selective heterocyclic sphingosine 1 phosphate receptor modulators
发明人：BOEHM MARCUS F; MARTINBOROUGH ESTHER; BRAHMACHARY ENUGURTHI; MOORJANI MANISHA; TAMIYA JUNKO; HUANG LIMING; YEAGER ADAM RICHARD
权利人:BOEHM MARCUS F; MARTINBOROUGH ESTHER; BRAHMACHARY ENUGURTHI; MOORJANI MANISHA; TAMIYA JUNKO; HUANG LIMING; YEAGER ADAM RICHARD; CELGENE INT II SÀRL
摘要:Compounds that selectively modulate the sphingosine 1 phosphate receptor are provided including compounds which modulate subtype 1 of the S1P receptor. Methods of chiral synthesis of such compounds is provided. Uses, methods of treatment or prevention and methods of preparing inventive compositions including inventive compounds are provided in connection with the treatment or prevention of diseases, malconditions, and disorders for which modulation of the sphingosine 1 phosphate receptor is medically indicated.