CAS: 453-72-5; 1-Fluoro-4-(Methylsulfonyl)-2-Nitrobenzene

上下游产品

CAS号455-15-2 4-氟苯基甲基砜 | CAS号97-07-4 4-氯-3-硝基苯基甲砜 | CAS号371-42-6 4-氟苯硫酚 | CAS号371-15-3 4-氟茴香硫醚 | CAS号349-88-2 4-氟苯磺酰氯 | CAS号387358-51-2 2-氟-5-甲磺酰基苯胺 | CAS号30388-44-4 4,6-二甲氧基-2-[苯基(... | CAS号21731-56-6 4-甲砜基-2-硝基苯胺 | CAS号849035-91-2 1-B°C-4-[4-(MET... | CAS号90558-40-0 {[4-(甲基磺酰基)-2-硝... | CAS号93001-20-8 1-[4-(甲基磺酰基)-2-... | CAS号97-10-9 2-硝基-4-甲磺酰基苯酚

📜对氟苯甲砜置于硫酸,硝酸体系中,化学反应生成 2-氟-5-甲基磺酰硝基苯
参考文献:Zahn; Zuber,Chemische Berichte,1953,Vol. 86,P. 172,180
标题:Zahn; Zuber,Chemische Berichte,1953,Vol. 86,P. 172,180

专利信息

专利号:US-2011021532-A1
优先权日:2008-04-22
标题 :Novel substituted heteroaromatic compounds as inhibitors of stearoyl-coenzyme a delta-9 desaturase
发明人：POWELL DAVID; LEBRUN MARIE-EVE; BHAT SATHESH; RAMTOHUL YEEMAN K
权利人:MERCK FROSST CANADA LTD
摘要:Substituted heteroaromatic compounds of structural formula I are inhibitors of stearoyl-coenzyme A delta-9 desaturase. The compounds of the present invention are useful for the prevention and treatment of conditions related to abnormal lipid synthesis and metabolism, including cardiovascular disease, such as atherosclerosis; obesity; Type 2 diabetes; insulin resistance; hyperglycemia; Metabolic Syndrome; neurological disease; cancer; and liver steatosis. Formula (I).