合成目标产物 P-Toluenesulfonyl Isocyanate 主要起始原料 Triphosgene And P-Toluenesulfonamide
(文献来源)合成步骤主要原料 Triphosgene 和 P-Toluenesulfonamide
P-Toluenesulphonyloxamoyl Chloride置于邻二氯苯体系中,化学反应生成 对甲基苯磺酰异氰酸酯 参考文献:The Reactions Of Sulfonamides With Oxalyl Chloride 标题:The Reactions Of Sulfonamides With Oxalyl Chloride 摘要: DOI:10.1021/jo01032A025
专利号:US-12338202-B2 优先权日:2021-09-10 标 题 :One pot synthesis of urea (meth)acrylates 发明人:BESTGEN SEBASTIAN; BEYER SILVIA 权利人:EVONIK OPERATIONS GMBH 摘要:A one-pot synthesis of polymerizable and acyclic urea (meth)acrylates, preferably mono(meth)acrylates, can be performed via in-situ synthesis of urea alcohols or amines followed by direct reaction with a (meth)acrylate reactive diluent. The urea alcohol/amine is obtained from isocyanates and alcohols, amines, or hydroxyamines. Subsequently, the reaction with the (meth)acrylate reactive diluent takes place and the urea (meth)acrylate is directly obtained either in solution with the reactive diluent, or as a pure material after removal of the reactive diluent.
专利号:WO-2024003243-A1 优先权日:2022-06-29 标 题 :Process for the synthesis of poly-4-hydroxybutyrate 发明人:SCHAUB THOMAS; BRUCHMANN BERND; RODEWALD DIETER; NICOLAS MATHIEU; FALCONNET ALBAN 权利人:BASF SE; UNIV HEIDELBERG RUPRECHT KARLS 摘要:Described are a process for the synthesis of poly-4-hydroxybutyrate, the use of a kit comprising (i) one or more bases comprising an alkaline metal cation and (ii) one or more alcohols in said process and to poly-4-hydroxybutyrate obtainable by said process.
专利号:WO-9013609-A1 优先权日:1989-05-01 标题 :Novel fluorescent pigment compositions and a process for their preparation and use of same 发明人:MALLAVARAPU LEO X 权利人:MALLAVARAPU LEO X 摘要:A process is disclosed for producing novel fluorescent pigment compositions with no formaldehyde or para-formaldehyde during their synthesis. The synthesis of these compositions is, for example, achieved by using an in situ reaction of epoxy resins of preferably up to a molecular weight of 20,000 with a sulfonamide compound, e.g., toluene sulfonamide, in the presence of a Lewis acid catalyst, followed by, preferably, the further reaction with an isocyanate, e.g., aliphatic isocyanate and/or para-toluene sulfonyl isocyanate. During this reaction, a fluorescent dye is incorporated into the molten mass.
专利号:US-4578514-A 优先权日:1984-11-01 标题 :Synthesis of sulfilimines 发明人:GETMAN DANIEL P 权利人:MONSANTO CO 摘要:Processes are disclosed for preparation of N-aryl-S,S-dihydrocarbylsulfilimines by reaction of phenylisocyanate compounds with hydrocarbyl sulfoxides. The sulfilimines can be rearranged to ortho-thioalkylene anilines and the reactions can be employed in a route for converting nitrobenzene compounds to ortho-thioalkylene anilines, which are useful intermediates for preparation of herbicidal compounds.
专利号:US-6602714-B1 优先权日:1999-11-09 标 题:Viscosity and mass sensor for the high-throughput synthesis, screening and characterization of combinatorial libraries 发明人:TAGGE CHRISTOPHER D; WILSON JR ROBERT B; OH SEAJIN; HIRSCHON ALBERT S; PLOEGER DALE W 权利人:STANFORD RES INST INT 摘要:Workstation, apparatuses and methods for the high-throughput synthesis, screening and/or characterization of combinatorial libraries. The invention relates to an array, which permits various high-throughput methods for synthesis, screening and/or characterization in the same array, without requiring sample transfer from the array. In a preferred embodiment, the synthesis, screening, and/or characterization steps are carried out in a highly parallel fashion, where more than one compound is synthesized, screened, and/or characterized at the same time. The invention may be practiced at the microscale. The array may comprise thermal channels, for regulating the temperature of the wells in the array. The wells of the array may comprise a membrane, which is used in various screening and characterization methods. The invention also relates to a covered array, comprising the array and an array cover, as well as an apparatus comprising the array, which comprises the array, an array cover and a stage. The array, array cover, and the stage may be modified as required for a variety of synthesis and/or analysis techniques. The array is easily interchangeable between different analytical instruments, and in an embodiment, the invention relates to an automated workstation, where the array is transferred between different synthesis, screening, and characterization stations. The invention also relates to a variety of methods for synthesis, screening, and characterization, which are adapted for combinatorial chemistry. Any of the embodiments of the invention may be used either alone or taken in various combinations.
专利号:WO-2024135609-A1 优先权日:2022-12-20 标 题:Linker for nucleic acid synthesis, carrier, and methods for producing same 发明人:HARI YOSHIYUKI; KAJINO Ryohei 权利人:SYNCREST INC 摘要:The purpose of the present invention is to newly provide a linker for nucleic acid synthesis and a carrier for solid-phase nucleic acid synthesis. Provided are a precursor to a linker for nucleic acid synthesis, a linker for nucleic acid synthesis, and a carrier for solid-phase nucleic acid synthesis.
参考标题:Pd(II)/cu(II)-Catalyzed Regio- And Stereoselective Synthesis Of (E)-3-Arylmethyleneisoindolin-1-Ones Using Air As The Terminal Oxidant 作者:So Won Youn,Tae Yun Ko,Young Ho Kim,Yun Ah Kim |发布日期:2018.12.21 摘要:Regio- And Stereoselective Synthesis Of (E)-3-Arylmethyleneisoindolin-1-Ones Via Pd(II)/cu(II)-Catalyzed One-Pot C-C/c-N Bond Forming Sequence Between Amides And Styrenes Is Reported. This Method Provides Facile And Rapid Access To A Diverse Range Of Such Compounds Using Readily Available Starting Materials Under Mild Aerobic Conditions With Good Functional Group Tolerance And High Selectivity And Efficiency
合成参考文献
摘要:Chen, P.; Liu, G.; Engle, K. M.; Yu, J.-Q., Science of Synthesis Knowledge Updates, (2013) 2, 95. 摘要:Campbell, M. J.; Toste, F. D., Science of Synthesis Knowledge Updates, (2012) 1, 165. 摘要:Aitken, R. A.; Meehan, A., Science of Synthesis Knowledge Updates, (2014) 3, 174. 摘要:Kubik, S., Science of Synthesis Knowledge Updates, (2013) 3, 262. 摘要:Mlostoń, G.; Heimgartner, H., Science of Synthesis Knowledge Updates, (2014) 4, 404.