CAS: 20567-38-8; 3-(4,5-Dimethoxy-2-Nitrophenyl)Acrylic Acid

该化合物是一种硝酸衍生物,其特征是甲氧基和硝基功能组,该化合物主要用于有机合成和制药研究,因为其具有多功能中间体的作用.其电子排泄式硝基化合物和甲氧替代成分增强了回活动性,使其对交叉反应和制造更复杂的分子具有价值.复合物质在标准条件下具有稳定性,并与各种合成方法相容.研究人员欣赏其一贯的纯度和明确界定的结构特性,这有助于药用化学和材料科学的精确应用.其在普通有机溶剂中的溶解性进一步增强了其在实验室环境中的实用性.

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CAS号14737-89-4 (E)-3-(3,4-二甲氧基... | CAS号141-82-2 丙二酸 | CAS号20357-25-9 6-硝基藜芦醛 | CAS号7697-37-2 硝酸 | CAS号64-19-7 冰醋酸 | CAS号91133-47-0 6,7-dimethoxy-3... | CAS号402932-81-4 (2E)-3-(4,5-Dih...

合成工艺路线路线简述

    📜3,4-二甲氧基肉酸酸置于硝酸,溶剂黄146体系中,化学反应生成4,5-二甲氧基-2-硝基肉桂酸
    参考文献:Sugasawa Et Al.,Yakugaku Zasshi/journal Of The Pharmaceutical Society Of Japan,1938,Vol. 58,P. 402;Engl.Ref.S.80
    标题:Sugasawa Et Al.,Yakugaku Zasshi/journal Of The Pharmaceutical Society Of Japan,1938,Vol. 58,P. 402;Engl.Ref.S.80

    海关参考信息

    专利信息


    专利号:US-6531470-B1
    优先权日:1998-01-23
    标题:Oxazolidinone combinatorial libraries, compositions and methods of preparation
    发明人:GORDEEV MIKHAIL F; LUEHR GARY W; PATEL DINESH V; NI ZHI-JIE; GORDON ERIC
    权利人:UPJOHN CO
    摘要:Oxazolidinones and methods for their synthesis are provided. Also provided are combinatorial libraries comprising oxazolidinones, and methods to prepare the libraries. Further provided are methods of making biologically active oxazolidinones as well as pharmaceutically acceptable compositions comprising the oxazolidinones. The methods of library preparation include the attachment of oxazolidinones to a solid support. The methods of compound preparation in one embodiment involve the reaction of an iminophosphorane with a carbonyl containing polymeric support.

    专利号:US-6562844-B2
    优先权日:1998-01-23
    标 题:Oxazolidinone combinatorial libraries, compositions and methods of preparation
    发明人:GORDEEV MIKHAIL F; LUEHR GARY W; PATEL DINESH V; NI ZHI-JIE; GORDON ERIC
    权利人:UPJOHN CO
    摘要:Oxazolidinones and methods for their synthesis are provided. Also provided are combinatorial libraries comprising oxazolidinones, and methods to prepare the libraries. Further provided are methods of making biologically active oxazolidinones as well as pharmaceutically acceptable compositions comprising the oxazolidinones. The methods of library preparation include the attachment of oxazolidinones to a solid support. The methods of compound preparation in one embodiment involve the reaction of an iminophosphorane with a carbonyl containing polymeric support.

    专利号:US-7002020-B1
    优先权日:1998-01-23
    标题:Oxazolidinone combinatorial libraries, compositions and methods of preparation
    发明人:GORDEEV MIKHAIL F; LUEHR GARY W; PATEL DINESH V
    权利人:UPJOHN CO
    摘要:Oxazolidinones and methods for their synthesis are provided. Also provided are combinatorial libraries comprising oxazolidinones, and methods to prepare the libraries. Further provided are methods of making biologically active oxazolidinones as well as pharmaceutically acceptable compositions comprising the oxazolidinones. The methods of library preparation include the attachment of oxazolidinones to a solid support. The methods of compound preparation in one embodiment involve the reaction of an iminophosphorane with a carbonyl containing polymeric support.

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    ✅ COA系统入驻 | 共享模式

    合成参考文献


    参考文献:10.1134/s1068162024605718
    摘要:Liu X, He J, Cheng W, Wang X, Zhang M, Wang S, Chen L, Zhang S, Zhou C, Zhou L, Zhang B, Wang D, Song Y, Wang X, Ji J. A Novel Piperine Derivative, NOHJ, Exerts Antibreast Cancer Effects by Inhibiting MDM2. Russ J Bioorg Chem. 2025 Jun;51(3):1070–82. doi: 10.1134/s1068162024605718.
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