CAS: 196868-63-0; 1-(5-Chloro-2-Methoxyphenyl)-3-(2-Methylquinolin-4-yl)Urea

主要参考文献

1: Kim W, Zou G, Pan W, Fricke N, Faizi HA, Kim SM, Khader R, Li S, Lee K, Escorba I, Vlahovska PM, Gao H, Ausubel FM, Mylonakis E. The Neutrally Charged Diarylurea Compound PQ401 Kills Antibiotic-Resistant and Antibiotic-Tolerant Staphylococcus aureus. mBio. 2020 Jun 30;11(3):e01140-20. doi: 10.1128/mBio.01140-20.
2: Qi B, Zhang R, Sun R, Guo M, Zhang M, Wei G, Zhang L, Yu S, Huang H. IGF-1R inhibitor PQ401 inhibits osteosarcoma cell proliferation, migration and colony formation. Int J Clin Exp Pathol. 2019 May 1;12(5):1589-1598.
3: Zhou X, Zhao X, Li X, Ping G, Pei S, Chen M, Wang Z, Zhou W, Jin B. PQ401, an IGF-1R inhibitor, induces apoptosis and inhibits growth, proliferation and migration of glioma cells. J Chemother. 2016;28(1):44-9. doi: 10.1179/1973947815Y.0000000026.

合成参考文献

参考文献:10.1124/mol.119.115964
摘要:Lee TD, Lee OW, Brimacombe KR, Chen L, Guha R, Lusvarghi S, Tebase BG, Klumpp-Thomas C, Robey RW, Ambudkar SV, Shen M, Gottesman MM, Hall MD. A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. Molecular Pharmacology. 2019 Nov;96(5):629–40. doi: 10.1124/mol.119.115964.