CAS: 670-80-4; N-(1-Cyclohexen-1-yl)Morpholine

该化合物是多用途的七环化合物,其特点是与环球环相连的一角细胞. 这一结构具有独特的回活动性,使其作为有机合成的中间体,特别是在制药和农用化学的制作方面,具有宝贵的价值.环球体为功能化提供场所,而单光环可增强各种反应条件下的溶解性和稳定性. 它平衡的脂性和电子施食特性使它适合医药化学的应用,例如生物活性分子的开发.该化合物的界定明确结构确保了合成途径的一贯性,有助于研究和工业过程的高效和可复制结果.

结构式图片

相似化合物

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上下游产品

CAS号110-91-8 吗啉 | CAS号108-94-1 环己酮 | CAS号1192-37-6 亚甲基环己烷 | CAS号110-83-8 环己烯 | CAS号177-12-8 1,2,4-trioxaspi... | CAS号13368-42-8 4-(三甲基硅基)吗啉 | CAS号75-77-4 三甲基氯硅烷 | CAS号1080-41-7 2-diethoxyphosp... | CAS号112092-00-9 2-(1-三氟甲基-2-硝基乙基)环己酮 | CAS号105702-16-7 2-(1,3-benzodio... | CAS号3580-38-9 2-苯甲酰环己酮 | CAS号533-60-8 2-羟基环己酮 | CAS号108-94-1 环己酮 | CAS号108790-85-8 methyl 1,1,3-tr... | CAS号14909-79-6 trans-2-Morphol... | CAS号90005-77-9 4,5,6,7-四氢-1,2-... | CAS号39207-65-3 2-异丁酰环己酮

合成工艺路线路线简述

  • 合成目标产物 N-(1-Cyclohexen-1-yl)Morpholine 主要起始原料 Morpholine And Cyclohexanone
  • (文献来源)合成步骤主要原料 Morpholine 和 Cyclohexanone
亚甲基环己烷,Alkaline Earth Salt Of/the/ Methylsulfuric Acid置于4 A Molecular Sieve,臭氧体系中,用 正戊烷 作为反应溶剂,化学反应 6.0H,反应生成 1-吗啉基-1-环己烯
参考文献:The Reactions Of The Ozonides With Secondary Amines: An Efficient And Novel Way To Prepare Tertiary Amine From Mono-And 1,1-Di-Substituted Alkenes Via Corresponding Ozonides
标题:The Reactions Of The Ozonides With Secondary Amines: An Efficient And Novel Way To Prepare Tertiary Amine From Mono-And 1,1-Di-Substituted Alkenes Via Corresponding Ozonides
摘要:
DOI:10.1016/s0040-4039(00)73982-7

海关参考信息

专利信息


专利号:US-4895996-A
优先权日:1988-10-17
标 题 :Synthesis of alkenes from enamines via hydroboration
发明人:GORALSKI CHRISTIAN T; SINGARAM BAKTHAN; BROWN HERBERT C
权利人:PURDUE RESEARCH FOUNDATION; DOW CHEMICAL CO
摘要:Alkenes are prepared by the hydroboration of enamines followed by an elimination reaction to form the alkene. This process has wide applicability and is useful for the stereospecific synthesis of [Z] isomers. It is preferred to use 9-borabicyclo[3.3.1 nonane as the hydroborating agent and to use methanol to catalyze the elimination reaction.

专利号:US-2005014954-A1
优先权日:2001-11-22
标 题:Pyrrole synthesis
发明人:OHRLEIN REINHOLD; BAISCH GABRIELE
摘要:The invention relates to a novel process for the preparation of N-substituted pyrroles, especially of formula (V), wherein the radicals are as defined in the description, by intermolecular aza-Wittig reaction starting from organic azides and 1,4-dioxo compounds. The invention relates also to novel iminophosphorane intermediates for this synthesis. The resulting pyrroles are useful, for example, in the organic synthesis of pharmaceuticals or other active substances and chemicals.

专利号:US-7514465-B2
优先权日:2004-11-16
标题 :Synthesis of N2-(substituted arylmethyl)-3-(substituted phenyl)indazoles as novel anti-angiogenic agents
发明人:KUO SHENG-CHU; HUANG LI-JIAU; LEE FANG-YU; TENG CHE-MING; SHIH MEI-LING; CHEN HUA-SIN
权利人:YUNG SHIN PHARM IND CO LTD
摘要:Novel compounds of 2-(substituted arylmethyl)-3-(substituted phenyl)-2H-indazoles and 1-(substituted arylmethyl)-3-(substituted phenyl)-1H-indazoles are synthesized, and useful as anti-angiogenic agents.

专利号:US-5229474-A
优先权日:1991-03-20
标题 :Synthesis of two-dimensional polymers by molecular recognition and chemical reaction among high molar mass monomers
发明人:STUPP SAMUEL I
权利人:UNIV ILLINOIS
摘要:A new variety of side chain liquid crystal polymers. The macromolecules of these materials are comb-shaped and differ from conventional side-chain liquid crystal polymers in that the comb's teeth are longer and semi flexible. The oligomeric side chains contain a long flexible spacer not only at their junction with the backbone but also in the center of the mesogen. Specific features of the systems include monosubstitution of enantiotopic protons in the central spacer by a cyano group and a long alkoxy tail at the terminus. An unusual property of these materials is a lower liquid crystal-isotropic transition temperature relative to that of their monomeric precursors.

专利号:US-8957260-B2
优先权日:2011-02-07
标题 :Process for the oxidation of mesitol
发明人:WEYRAUCH JAN PHILIPP; WEIS MARTINE; TELES JOAQUIM HENRIQUE; EBEL KLAUS; DEGLMANN PETER
权利人:WEIS MARTINE; TELES JOAQUIM HENRIQUE; EBEL KLAUS; DEGLMANN PETER; WEYRAUCH VIVIEN ELLINOR; WEYRAUCH GUNHILD; BASF SE
摘要:The invention relates to a process for the oxidation of mesitol with singlet oxygen, which is released from hydrogen peroxide, this release taking place in the presence of a bismuth compound as catalyst. In the process, 2,4,6-trimethylquinol is formed in high yield and selectivity as product, which can be used in further reactions for the synthesis of vitamins and in particular of vitamin A and vitamin E.

专利号:US-5502226-A
优先权日:1994-11-14
标 题:Process of preparing ω-hydroxy acids
发明人:CHO SUK H; DEFLORIO VICTOR
权利人:ARDEN ELIZABETH CO
摘要:A new synthesis of omega -hydroxy acids, which employs commercially available starting materials and lowers the cost of production. The process involves coupling a fatty acyl group by enamine chemistry, followed by a ring expansion and selective reduction of ketoacid.
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合成参考文献


摘要:Shindo, M.; Yoshikawa, T.; Yaji, K., Science of Synthesis, (2009) 46, 364.
摘要:Aguilar, E.; López, L. A., Science of Synthesis Knowledge Updates, (2014) 2, 93.
摘要:von Angerer, S., Science of Synthesis Knowledge Updates, (2011) 1, 137.
摘要:Haufe, G., Science of Synthesis Knowledge Updates, (2019) 3, 289.
摘要:Margaretha, P., Science of Synthesis Knowledge Updates, (2010) 4, 438.
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