CAS: 61-75-6; N-(2-Bromobenzyl)-N,N-Dimethylethanaminium 4-Methylbenzenesulfonate

上下游产品

2-bromo-N,N-dimethylbenzylamine ethyl ester of p-toluenesulfonic acid

📜(2-溴苯基)二甲胺,对甲苯磺酸乙酯 以 丙酮 作为反应溶剂,化学反应 12.0H,反应生成 溴苄乙胺
参考文献:Process For The Production Of Bretylium Tosylate
标题:Process For The Production Of Bretylium Tosylate
摘要:一种生产药用级对甲苯磺酸布雷替利的方法,包括低量的致突变杂质.该方法包括形成纯度低于99.5%的对甲苯磺酸布雷替利,并通过以下步骤纯化对甲苯磺酸布雷替利:I)将对甲苯磺酸布雷替利与丙酮和乙酸乙酯混合物形成悬浮液;ii)过滤悬浮液以获得纯化的对甲苯磺酸布雷替利.所生产的对甲苯磺酸布雷替利的纯度至少为99.5%,适当地含有少于0.5 Ppm的潜在致突变杂质乙基对甲苯磺酸酯.所生产的对甲苯磺酸布雷替利还适当地含有少于0.5 Ppm的潜在致突变杂质2-溴苯甲基溴化物.

专利信息

专利号:US-10925977-B2
优先权日:2006-10-05
标 题 :Efficient synthesis of chelators for nuclear imaging and radiotherapy: compositions and applications
发明人：YANG DAVID J; YU DONGFANG; THOMPSON ANDREW S
权利人:YANG DAVID J; YU DONGFANG; THOMPSON ANDREW S; CEIL POINT LLC; UNIV TEXAS
摘要:Novel methods of synthesis of chelator-targeting ligand conjugates, compositions comprising such conjugates, and therapeutic and diagnostic applications of such conjugates are disclosed. The compositions include chelator-targeting ligand conjugates optionally chelated to one or more metal ions. Methods of synthesizing these compositions in high purity are also presented. Also disclosed are methods of imaging, treating and diagnosing disease in a subject using these novel compositions, such as methods of imaging a tumor within a subject and methods of diagnosing myocardial ischemia.

专利号:US-7329767-B2
优先权日:2003-10-03
标 题:Conjugated dienamides, methods of production thereof, compositions containing same and uses thereof
发明人：DEWIS MARK L; JOHN THUMPLASSERIL V; ECKERT MARKUS A; COLSTEE JAN HERMAN; DA COSTA NEIL C; PEI TAO
权利人:INT FLAVORS & FRAGRANCES INC
摘要:Described are mixtures of at least four of the alkadienamides defined according to the structure: n nwherein R represents C 1 -C 2 n-alkyl; R 1 is 2-methyl-1-propyl and R 2 is hydrogen, or R 1 and R 2 taken together is a moiety having the formulan n nwherein n is 4 or 5, or compositions containing substantial concentrations of such mixtures, prepared according to novel processes: (a) extraction of a ground substantially dried fruit of one of the Piper species, Piper longum Linn or Piper peepuloides ; (b) natural product-forming synthesis; or (c) synthetic product-forming synthesis. Also described are uses of the thus-formed products for augmenting, enhancing or imparting an aroma, taste, chemesthetic effect and/or antibacterial effect in or to a consumable material and/or in the oral cavity and/or on the mammalian epidermis.

专利号:US-6316487-B1
优先权日:1993-06-16
标 题:Compounds for treatment of cardiac arrhythmia synthesis, and methods of use
发明人：DRUZGALA PASCAL; MILNER PETER G
权利人:ARYX THERAPEUTICS
摘要:The subject invention pertains to novel compounds, and compositions comprising the compounds, for the treatment of cardiac arrhythmias. The subject invention further concerns a method of making the novel compounds. The novel compounds are rapidly metabolized analogs of amiodarone, having the distinct and advantageous characteristic of being metabolized to a less lipophilic compound. The new compounds can have particular utility for treating life-threatening ventricular tachyarrhythmias, especially in patients with congestive heart failure (CHF). The product can also provide effective management for ventricular arrhythmias and supraventricular arrhythmias, including atrial fibrillation and re-entrant tachyarrhythmias involving accessory pathways.

专利号:KR-101513003-B1
优先权日:2006-10-05
标 题 :Efficient synthesis of chelators for nuclear imaging and radiotherapy compositions and applications

专利号:US-10814013-B2
优先权日:2006-10-05
标 题 :Efficient synthesis of chelators for nuclear imaging and radiotherapy: compositions and applications

专利号:AU-2007308022-A2
优先权日:2006-10-05
标题 :Efficient synthesis of chelators for nuclear imaging and radiotherapy: compositions and applications