CAS: 5219-61-4; 2-(Phenylthio)Acetonitrile

上下游产品

sodium thiophenolate chloroacetonitrile α-(phenylthio)acetamide iodoacetonitrile2-(phenylsulfonyl)acetonitrile α-(phenylthio)-pentyl cyanide 2-methyl-2-phenylsulfanylpropanenitrile 2-(phenylthio)butanenitrile

📜2-(苯基硫代)乙胺盐酸盐置于ammonium Hydroxide,氧气体系中,110.0 °C,200.0 Kpa 条件下,以75%的收率获得产物苯基腈乙基硫醚
参考文献:使用纳米级基于co 3 O 4的催化剂通过可持续的需氧氧化从胺类合成腈†
标题:使用纳米级基于co 3 O 4的催化剂通过可持续的需氧氧化从胺类合成腈†
摘要:描述了在温和条件下胺的选择性氧化以良性合成腈的方法.该转化成功的关键是可重复使用的基于氧化钴的纳米催化剂的应用.所得腈构成有机合成中的关键前体和中心中间体.
DOI:10.1039/c6Ob00184J

专利信息

专利号:US-4536599-A
优先权日:1978-08-22
标题:Synthesis of amine derivatives
发明人：MASUKO FUJIO; KATSURA TADASHI
权利人:SUMITOMO CHEMICAL CO
摘要:An amine of the formula, ##STR1## wherein R 1 , R 2 , R 3 , R 4 and R 5 are each hydrogen, alkyl or the like and n is 1, 2 or 3, including α-phenyl-β-(p-tolyl)-ethylamine, which is useful as an optically resolving agent, an intermediate of medicines and the like, is effectively produced by a novel process comprising hydrolysis of the corresponding nitrile of the formula, ##STR2## wherein R 1 , R 2 , R 3 , R 4 , R 5 and n are the same as above, followed by alkali-decomposition of the resulting amide of the formula, ##STR3## wherein R 1 , R 2 , R 3 , R 4 , R 5 and n are the same as above. An amide including the above one is effectively produced by hydrolysis of the corresponding nitrile in the presence of a base and hydrogen peroxide using an organic quaternary ammonium salt and/or a tertiary amine as a catalyst.

专利号:EP-0040896-B1
优先权日:1978-08-22
标题:Synthesis of amides

专利号:EP-0008532-A1
优先权日:1978-08-22
标 题 :Synthesis of amines

专利号:EP-0040896-A2
优先权日:1978-08-22
标 题 :Synthesis of amides