CAS: 3920-50-1; Pyrazole-3-Carboxaldehyde

相似化合物

15366-34-4 5932-27-4 1621-91-6

上下游产品

CAS号111573-59-2 3-二甲氧基甲基-1H-吡唑 | CAS号186581-53-3 重氮甲烷 | CAS号624-67-9 炔丙醛 | CAS号111573-59-2 3-二甲氧基甲基-1H-吡唑 | CAS号397329-07-6 1-(4-烯丙基苯基)吡唑-3-甲醛

📜3-羟甲基吡唑置于activated Manganese(Iv) Oxide体系中,用 乙酸乙酯 用作溶剂,以62 %的收率获得1H-吡唑-3-甲醛
参考文献:双三齿 N-供体配体支持的双核铜 (I) 配合物:开启酪氨酸酶活性
标题:双三齿 N-供体配体支持的双核铜 (I) 配合物:开启酪氨酸酶活性
摘要:双核铜 (I) 配合物由具有两个亚胺功能的双三齿n-供体配体支持,介导单酚转化为其相应的邻醌,这与由具有胺功能的配体支持的类似配合物形成对比.
Doi:10.1002/ejic.202200509

专利信息

专利号:WO-2017089470-A1
优先权日:2015-11-27
标 题:Process for the synthesis of aryldiazonium salts using nitrogen oxides in oxygen-containing gas streams, especially from industrial waste gases
发明人：HOFMANN DAGMAR; HOFMANN JOSEFA; HEINRICH MARKUS
权利人:Friedrich-Alexander-Universität Erlangen-Nürnberg
摘要:The present invention relates to a process for the synthesis of aryldiazonium salts using nitrogen oxides in oxygen-containing gas streams, especially from industrial waste gases.

专利号:US-2013338369-A1
优先权日:2011-03-07
标 题 :Process for the Synthesis of Aminobiphenylene
发明人：HEINRICH MARKUS; PRATSCH GERALD
权利人:HEINRICH MARKUS; PRATSCH GERALD; BASF SE
摘要:The present invention relates to a process for the synthesis of 2-aminobiphenylene and derivatives thereof by reacting a benzene diazonium salt with an aniline compound under basic reaction conditions.

专利号:US-9845282-B1
优先权日:2016-08-12
标题 :Palladium catalyzed synthesis of ester compounds
发明人：EL ALI BASSAM M; IBRAHIM MANSUR B; SULEIMAN RAMI K
权利人:UNIV KING FAHD PET & MINERALS
摘要:A catalytic process for synthesizing an ester compound, and a catalytic process for synthesizing an amide compound, wherein a solid-supported palladium catalyst is used to catalyze an alkoxycarbonylation reaction of an aryl halide to form the ester compound, or to catalyze an aminocarbonylation reaction of an aryl halide to form the amide compound. Various embodiments of each of the processes are also provided.

专利号:US-9656965-B2
优先权日:2013-09-05
标题:Procedure for the synthesis of N-benzyl-N-cyclopropyl-1H-pyrazole-4-carboxamide derivatives
发明人：BRUCHNER PETER; PAZENOK SERGII
权利人:BAYER CROPSCIENCE AG
摘要:A new one-step process for the preparation of pyrazole carboxamide derivatives of the general formula (I) n nby reaction of 3-(difluoromethyl)-5-fluoro-1-methyl-1H-pyrazole-4-carbaldehyde with an amine or its salt.

专利号:EP-1253146-B1
优先权日:2001-04-27
标题 :Process for the synthesis of substituted furancarboxylates
发明人：POECHLAUER PETER; GANGLBERGER THORSTEN; MAYRHOFER HERBERT
权利人:DSM FINE CHEM AUSTRIA GMBH
摘要:Alkyl 4-amino-2-alkyl-5-substituted-furan-3-carboxylates (I) are prepared by reacting a hydroxy-nitrile of formula R1-CH(OH)-CN (II) with a beta -ketoacid ester (III) in the presence of a metal halide catalyst and an inert organic solvent at 0 - 120 degrees C, followed by removing the catalyst and recovering (I).. Alkyl 4-amino-2-alkyl-5-substituted-furan-3-carboxylates of formula (I) are prepared by reacting a hydroxy-nitrile of formula R1-CH(OH)-CN (II) with a beta -dicarbonyl compound of formula R2-CO-CH2-COOR3 (III) in the presence of a metal halide catalyst and an inert organic solvent at 0 - 120 degrees C, followed by removing the catalyst and recovering (I). R1 = 1-18C alkyl, alkenyl or alkynyl (all optionally substituted by inert groups), or an optionally substituted aromatic or heterocyclic group; and R2, R3 = 1-4C alkyl.

专利号:US-2024239799-A1
优先权日:2021-04-02
标 题:(s)-1-(5-((pyridin-3-yl)thio)pyrazin-2-yl)-4'h,6'h-spiro[piperidine-4,5'-pyrrolo [1,2-b]pyrazol]-4'-amine derivatives and similar compounds as shp2 inhibitors for the treatment of e.g. cancer
发明人：DI FABIO ROMANO; MONTALBETTI CHRISTIAN; PETROCCHI ALESSIA; GRILLO ALESSANDRO; RANDAZZO PIETRO; ROSSETTI ILARIA; CIAMMAICHELLA ALINA
权利人:C N C C S S C A R L COLLEZIONE NAZ DEI COMPOSTI CHIMICI E CENTRO SCREENING; IRBM S P A
摘要:The present invention relates to compounds of formula (I). The compounds of the formula (I) are e.g. (S)-1-(5-((pyridin-3-yl)thio) pyrazin-2-yl)-41H,6′H-spiro[piperidine-4,5′-pyrrolo[1,2-b]pyrazol]-41-amine derivatives and similar compounds. The present invention also relates to the compounds of formula (I) for use as Src homology phosphotyrosine phosphatase 2 (SHP2) inhibitors in methods of treatment of e.g. cancer, cardiovascular diseases, immunological disorders, autoimmune disorders, fibrosis, ocular disorders, systemic lupus erythematosus, diabetes, neutropenia, and combinations thereof. The present invention also relates to pharmaceutical compositions containing said compounds and to their methods of synthesis.