CAS: 35613-44-6; Methyl 2-(2-Aminophenyl)Acetate

该化合物是苯乙酸的一种酯衍生物,在苯环的正方形位置上有一个有地雷功能的组别,该化合物由于其双重反应性,对有机合成感兴趣,该化合物提供了酯体和地雷组,供进一步功能化之用;它是制备药品,农用化学品和精美化学品的多种媒介;电饱和氨基氨基组的存在增强了其在电光替代反应中的效用,而甲基酯则提供了水解或转化的处理器;在标准条件下和特征精密的再活动下,其稳定性成为合成应用的一个实用选择.

结构式图片

上下游产品

CAS号30095-98-8 (2-硝基苯基)乙酸甲酯 | CAS号3740-52-1 2-硝基苯乙酸 | CAS号347877-90-1 methyl 2-(is°Cy... | CAS号67-56-1 甲醇 | CAS号3342-78-7 2-氨基苯乙酸 | CAS号59-48-3 2-吲哚酮 | CAS号67-56-1 甲醇 | CAS号824-21-5 1-甲基吲哚啉 | CAS号400797-94-6 4-(2-氧代吲哚啉-1-基)...

合成工艺路线路线简述

    📜2-硝基苯乙酸置于盐酸,Palladium 10% On Activated Carbon,氢气体系中,用 乙酸乙酯 用作溶剂,化学反应生成(2-氨基-苯基)-乙酸甲酯
    参考文献:Intramolecular C-o/c-s Bond Insertion Of α-Diazoesters For The Synthesis Of 2-Aryl-4H-Benzo[d][1,3]Oxazine And 2-Aryl-4H-Benzo[d][1,3]Thiazine Derivatives
    标题:Intramolecular C-o/c-s Bond Insertion Of α-Diazoesters For The Synthesis Of 2-Aryl-4H-Benzo[d][1,3]Oxazine And 2-Aryl-4H-Benzo[d][1,3]Thiazine Derivatives
    摘要:使用10 Mol% Cu(Otf)2实现2-(2-芳胺基苯基)-2-重氮乙酸酯/2-重氮-2-(2-芳硫代胺基苯基)乙酸酯的分子内c-O/c-S插入,生成苯并噁嗪/苯并噻嗪.
    Doi:10.1039/c4Ra08208G

    海关参考信息

    专利信息


    专利号:US-9884844-B2
    优先权日:2012-12-31
    标 题:Heterocyclic compounds and methods of use thereof
    发明人:FANG QUN KEVIN; CAMPBELL UNA; SPEAR KERRY L
    权利人:SUNOVION PHARMACEUTICALS INC; SUNOVION PHARMACEUTICALS INC
    摘要:Provided herein are heterocyclyl compounds, methods of their synthesis, pharmaceutical compositions comprising the compounds, and methods of their use. The compounds provided herein are useful for the treatment, prevention, and/or management of various neurological disorders, including but not limited to, psychosis and schizophrenia.

    专利号:US-7368592-B1
    优先权日:2000-10-04
    标题:Process for the preparation of alkyl n-alkylanthranilate
    发明人:BERG CARSTEN
    权利人:PROM LTD
    摘要:This invention is directed to a process of preparing alkyl N-alkylanthranilate, specially Methyl N-methylanthranilate, represented by Formula (I), in a one pot synthesis, using available and cheap commercial chemicals such as Isatoic anhydride, solid sodium hydroxide, dimethyl sulfate and methanol. Purity of the crude product is about 97% and yield 85%.

    专利号:US-2006211603-A1
    优先权日:2004-08-18
    标 题:Ramoplanin derivatives possessing antibacterial activity
    发明人:RAJU BORE G; CIABATTI ROMEO; MAFFIOLI SONIA I; SINGH UPINDER; ROMANO GABRIELLA; MICHELUCCI ELENA; TISENI PAOLO S; CANDIANI GIANPAOLO; KIM BUM; O'DOWD HARDWIN
    权利人:VICURON PHARM INC
    摘要:Novel ramoplanin derivatives are disclosed. These ramoplanin derivatives exhibit antibacterial activity. As the compounds of the subject invention exhibit potent activities against gram positive bacteria, they are useful antimicrobial agents. Methods of synthesis and of use of the compounds are also disclosed.

    专利号:CN-101698647-B
    优先权日:2009-10-30
    标 题 :Synthesis method of 2,5-diamino benzene ethanol

    专利号:CN-101698647-A
    优先权日:2009-10-30
    标题 :Synthesis method of 2,5-diamino benzene ethanol

    专利号:CN-113429308-A
    优先权日:2021-06-16
    标题 :The synthesis process of diclofenac sodium

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    品牌试剂参考报价(招募中)

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    合成参考文献


    摘要:Joule, J. A., Science of Synthesis Knowledge Updates, (2010) 2, 176.
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