CAS: 161220-53-7; Fmoc-Ala-Ala-Pro-Oh
- 英文名称Fmoc-Ala-Ala-Pro-Oh
- 中文名称1-[N-[N-[9H-芴-9-基甲氧羰基]-L-丙氨酰]-L-丙氨酰]-L-脯氨酸
- 其它别名FM°C-ALA-ALA-PRO-OH; FM°C-L-ALANYL-L-ALANINE PROLINE
- CAS编号161220-53-7
- MFCD编号:MFCD01862421
- 分子式:C26H29N3O6分子量:479.52
- 产品CID: 813610
- 产品分类生物化工 → 氨基酸及其衍生物 → 脯氨酸类衍生物
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2905130000-正丁醇
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专利信息
专利号:US-2024124517-A1
优先权日:2020-12-25
标题:Method for producing peptide compound containing n-substituted-amino acid residue
发明人：MORITA YUYA; NOMURA KENICHI
权利人:CHUGAI PHARMACEUTICAL CO LTD
摘要:An object of the present invention is to provide a method for efficiently producing a high-purity peptide compound with a high yield. It has been found that the object can be achieved by supporting a peptide on a solid phase synthesis resin prior to a first elongation reaction in a solid phase process.
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主要参考文献
参考标题:Free Amino Group Transfer Via α‐amination Of Native Carbonyls作者:Minghao Feng,Anthony J. Fernandes,Ana Sirvent,Eleonora Spinozzi,Saad Shaaban,Nuno Maulide |发布日期:2023.7.10
摘要:An Amino Group Transfer Strategy Was Developed To Install Free Nh2 To The α-Position Of Native Carbonyls Under Mild Conditions. The Resulting Primary α-Aminated Products Are Amenable To In Situ Peptide Coupling Or Pictet-Spengler Cyclization In One-Pot Procedures. We Anticipate This Method To Provide A General Platform Towards The Synthesis Of Amines, Ultimately Opening Exciting Avenues In The Synthesis
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