CAS: 13009-99-9; 4-(Aminomethyl)Benzenesulfonamide Acetate

5-N-(4-Nitrobenzyloxycarbonyl)-2-Thia-5-Azabicyclo[2.2.1]Hept-3-One,(4R,5S,6S)-4Nitrobenzyl 6-((R)-1-Hydroxyethyl)-4-Methyl-7-Oxo-3-(((3S,5S)-5-((4-Sulfamoylbenzyl)Carbamoyl)Pyrrolidin-3-yl)Thio)-1-Azabicyclo[3.2.0]Hept-2-Ene-2-Carboxylate,三乙胺,乙酸乙酯置于氮,水,盐酸,碳酸氢钠,Sodium Sulfate-Iii,乙酸乙酯,醋酸磺胺米隆体系中,用 N,N-二甲基甲酰胺 用作溶剂,以to Obtain 3300 G Of A Solid (I.E. Intermediate 2) With A Yield Of 79.46%的收率获得醋酸磺胺米隆
参考文献:Crystalline Form Of Carbapenem Derivative Or Its Hydrates And Preparation Methods And Uses Thereof
标题:Crystalline Form Of Carbapenem Derivative Or Its Hydrates And Preparation Methods And Uses Thereof
摘要:本发明涉及碳青霉烯衍生物的晶体形式或其水合物及其制备方法.具体而言,本发明涉及由公式(I)表示的碳青霉烯衍生物(4R,5S,6S)-6-((R)-1-羟乙基)-4-甲基-7-氧代-3-(((3S,5S)-5-((4-磺酰苯基)氨基)吡咯烷-3-基)硫)-1-氮杂双环[3.2.0]庚-2-烯-2-羧酸的晶体形式或其水合物,其特征在于使用cu-Ka辐射表示的x射线粉末衍射图谱在2θ处具有特征峰18.9+/-0.2,19.4+/-0.2,21.0+/-0.2,21.7+/-0.2和23.4+/-0.2,以及其制备方法和在制备治疗和/或预防传染病药物方面的用途,以及包含该化合物和一种或多种药用载体和/或稀释剂的制药组合物.

专利信息

专利号:EP-4339199-A2
优先权日:2017-10-04
标题:Synthesis of cantharidin

专利号:US-9907753-B2
优先权日:2010-03-19
标 题 :Lipid vesicle compositions and methods of use
发明人：IRVINE DARRELL J; MOON JAEHYUN
权利人:MASSACHUSETTS INST TECHNOLOGY
摘要:The invention provides delivery systems comprised of stabilized multilamellar vesicles, as well as compositions, methods of synthesis, and methods of use thereof. The stabilized multilamellar vesicles may comprise prophylactic, therapeutic and/or diagnostic agents.

专利号:ES-2977612-T3
优先权日:2017-10-04
标题 :Synthesis of cantharidin

专利号:JP-7411545-B2
优先权日:2017-10-04
标题:Synthesis of cantharidin

专利号:KR-20200065031-A
优先权日:2017-10-04
标 题:Synthesis of cantharidin

专利号:CA-3078325-A1
优先权日:2017-10-04
标 题:Synthesis of cantharidin