CAS: 128524-26-5; ((2S,5R)-5-(5-Methyl-2,4-Dioxo-3,4-Dihydropyrimidin-1(2H)-yl)Tetrahydrofuran-2-yl)Methyl Tetrahydrogen Triphosphate, Sodium Salt
该化合物是一种经修改的核糖酸三磷酸类盐,其中甲状腺胺的3'羟氧组被氢取代.这种结构改变使甲状腺成为DNA合成中的链终止器,使其对Sanger测序和聚合酶研究等应用具有价值.锂盐形式提高了溶解性和水溶性,促进了水溶性的稳定,促进了精确的实验使用.它的高纯度和一贯性能确保酶反应的可靠结果.这种化合物在分子生物学研究中特别有用,需要控制DNA延展期.在建议的条件下适当储存保持其完整性,供长期使用.
- 英文名称((2S,5R)-5-(5-Methyl-2,4-Dioxo-3,4-Dihydropyrimidin-1(2H)-yl)Tetrahydrofuran-2-yl)Methyl Tetrahydrogen Triphosphate, Sodium Salt
- 中文名称((2S,5R)-5-(5-甲基-2,4-二氧代-3,4-二氢嘧啶-1(2H)-基)四氢呋喃-2-基)甲基三磷酸酯,钠盐
- IUPAC名称((2S,5R)-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl)methyl tetrahydrogen triphosphate, sodium salt
- 其它别名Dttp/ddttp Sodium Salt; 3'-Deoxythymidine-5'-O-Triphosphate/2',3'-Dideoxythymidine-5'-O-Triphosphate Sodium Salt; 3’-Deoxythymidine-5’-O-Triphosphate(Dttp),Sodiumsalt/2’,3’-Dideoxythymidine-5’-O-Triphosphate; 3’-Deoxythymidine5’-Triphosphate*sodium; 3′-Deoxythymidine 5′-Triphosphate Sodium Salt Solution; 3'-Deoxythymidine 5'-Triphosphate Sodium Salt (Ddttp); 2',3'-Dideoxythymidine-5'-Triphosphate, Sodium Salt Solution
- CAS编号128524-26-5
- MFCD编号:MFCD00079155
- 分子式:C10H17N2NaO13P3分子量:489.16
- 产品CID: 445222
- 产品分类有机原料→生命科学→核苷&核苷酸→修饰核苷酸
相似化合物
27821-54-1 95648-78-5 365-07-1物理性质
合成工艺路线路线简述
海关参考信息
- 2905122000-异丙醇
2905310000-1,2-乙二醇
2905320000-1,2-丙二醇
2909110000-乙醚 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
供应商参考报价(招募中)
品牌试剂参考报价(招募中)
📌 第三方产品分析报告
主要参考文献
[参考文献]: E Matthes, Et Al. Inhibition Of Hiv-Associated Reverse Transcriptase By Sugar-Modified Derivatives Of Thymidine 5'-Triphosphate In Comparison To Cellular Dna Polymerases Alpha And Beta. Biochem Biophys Res Commun. 1987 Oct 14;148(1):78-85.[参考文献]: Elena N Ilina, Et Al. Mutation In Ribosomal Protein S5 Leads To Spectinomycin Resistance In Neisseria Gonorrhoeae. Front Microbiol. 2013 Jul 10:4:186.
[参考文献]: Femi J Olorunniji, Et Al. Nicked-Site Substrates For A Serine Recombinase Reveal Enzyme-Dna Communications And An Essential Tethering Role Of Covalent Enzyme-Dna Linkages. Nucleic Acids Res. 2015 Jul 13;43(12):6134-43.
[参考文献]: K Ono, Et Al. Inhibition Of The Activity Of Dna Polymerase Alpha By 2',3'-Dideoxythymidine 5'-Triphosphate. Biochem Biophys Res Commun. 1979 Jun 27;88(4):1255-62.
[参考文献]: Kevin A Fiala, Et Al. Mechanistic Consequences Of Temperature On Dna Polymerization Catalyzed By A Y-Family Dna Polymerase. Nucleic Acids Res. 2008 Apr;36(6):1990-2001.
📝 需求与反馈
尽可能描述清楚需求与问题信息
