CAS: 126631-93-4; Fmoc-8-Aoc-Oh

相似化合物

1002-57-9 30100-16-4 27991-81-7

上下游产品

CAS号1002-57-9 8-氨基辛酸 | CAS号82911-69-1 9-芴甲基-N-琥珀酰亚胺碳酸酯

📜8-氨基辛酸置于甲醇体系中,用 二氯甲烷 用作溶剂,化学反应 3.5H,反应生成N-Fmoc-8-氨基辛酸
参考文献:Versatile Method For The Detection Of Covalently Bound Substrates On Solid Supports By Dart Mass Spectrometry
标题:Versatile Method For The Detection Of Covalently Bound Substrates On Solid Supports By Dart Mass Spectrometry
摘要:Analysis Of Substrates Directly On Solid Phase Resins Without The Need For Separate Cleavage Conditions Remains An Outstanding Challenge In The Field Of Solid Phase Synthesis. We Now Present The First Example Of Simultaneous Cleavage And Mass Spectrometric Analysis Of Peptides From Solid Supports Using Direct Analysis In Real Time (Dart) Mass Spectrometry. We Have Shown That This Method Is Compatible With A Diverse Array Of Solid Phase Resins And Is Suitable For Analysis Of Both Peptides And Organic Substrates.
Doi:10.1021/ol201404V

专利信息

专利号:US-2025090698-A1
优先权日:2018-11-27
标题 :Small molecule inhibitors for early diagnosis of prostate specific membrane antigen cancers and neurodegenerative diseases
发明人：CHELVAM VENKATESH; SENGUPTA SAGNIK; KRISHNAN MENA ASHA; PANDIT AMIT
权利人:INDIAN INSTITUTE OF TECH INDORE
摘要:Accordingly, embodiments herein disclose a conjugate D-E-F having binding affinity≤60 nM; wherein D comprises AAPT ligand or derivative thereof, E comprises a spacer comprising AA1, AA2, AA3 and/or AA4 and F is a chelating group. The conjugate also comprising AAPT ligand conjugated arene chelating linker for delivery of 99mTc radioisotope. Another embodiment also discloses a AAPT-PCa DOTA bioconjugate. An embodiment also discloses method of solid phase synthesis of AAPT-ligand. It also discloses a method of solid phase synthesis of AAPT-PCa DOTA bioconjugate for delivering of radioisotopes.

专利号:US-2007179100-A1
优先权日:2003-04-09
标 题:Protected monomers
发明人：MANOHARAN MUTHIAH
权利人:MANOHARAN MUTHIAH
摘要:This invention relates to protected monomers for the synthesis of iRNA agents.

专利号:US-7118737-B2
优先权日:2000-09-08
标题:Polymer-modified synthetic proteins
发明人：KOCHENDOERFER GERD G; BOTTI PAOLO; BRADBURNE JAMES A; CHEN SHIAH-YUN; CRESSMAN SONYA; HUNTER CHRISTIE L; KENT STEPHEN B H; LOW DONALD W; WILKEN JILL G
权利人:AMYLIN PHARMACEUTICALS INC
摘要:The present invention relates to methods and compositions for modifying peptides, polypeptides and proteins with polymers, especially glyco-mimetic polymers, so as to improve their biological activity or pharmacokinetic properties. The invention further provides methods and uses for such polymer-modified peptides, polypeptides and proteins. The invention is particularly suitable for use in the synthesis of polymer-modified synthetic bioactive proteins (FIG. 1 D), and of pharmaceutical compositions that contain such proteins.