CAS: 114040-31-2; Trimagnesium,(2R)-2-[(1S)-1,2-Dihydroxyethyl]-3,4-Dihydroxy-2H-Furan-5-One,Diphosphate

维生素 C,三氯氧磷,氢氧化钾,盐酸,Magnesiumacetate置于吡啶,水,L-Ascorbic Acid 2-Phosphate,维他命c磷酸镁盐,丙酮体系中,用 吡啶,水 用作溶剂,化学反应 2.5H,以to Obtain 65 G Of Magnesium L-Ascorbic Acid-2-Phosphate的收率获得维他命c磷酸镁盐
参考文献:Process For Producing Ascorbic Acid Derivative
标题:Process For Producing Ascorbic Acid Derivative
摘要:通过处理含有抗坏血酸-2-磷酸盐或抗坏血酸-2-硫酸盐的酸性水溶液,使用多孔吸附剂(如活性炭)可以高产得到抗坏血酸衍生物的金属盐或取代或非取代铵盐.然后,通过处理含有有机酸的金属盐或取代或非取代铵盐离子的碱性水溶液来洗脱所需的抗坏血酸衍生物的盐.

专利信息

专利号:US-6774114-B2
优先权日:2000-04-10
标 题:Topical application of immixture of ascorbic acid + ascorbic acid compounds for augmenting the synthesis of epidermal ceramides
发明人：CASTIEL ISABELLE; FERRARIS CORINNE; LAVALLE-BOUCHARD ARMELLE
权利人:OREAL
摘要:Synergistic immixtures of ascorbic acid with at least one monosaccharide ester of ascorbic acid and/or at least one metal salt of phosphorylated ascorbic acid more effectively increase the synthesis of epidermal ceramides in human skin, especially types IV to VII ceramides, as well as improve the barrier function, moisture content and/or suppleness/surface appearance of the skin and which otherwise combat/prevent intrinsic aging thereof and are useful for the treatment of dermatitis.

专利号:EP-1334714-B1
优先权日:2002-02-07
标 题:Use of ascorbic acid to stergthen the dermal-epidermal junction
发明人：BERNERD FRANCOISE
权利人:OREAL
摘要:Cosmetic use of a composition (A), comprising ascorbic acid or its analog (I) in a cosmetic medium, is claimed for improving the cohesion of the epidermis-dermis junction, promoting the synthesis of tenascin and/or promoting the synthesis of type VII collagen. Independent claims are included for: (i) use of (I) for the production of a pharmaceutical (specifically dermatological) composition (B) for treating disorders associated with deficiency in cohesion of the epidermis-dermis junction, synthesis of tenascin and/or synthesis of type VII collagen; and (ii) use of (I) in the culture medium for reconstructed skin, for improving the cohesion of the epidermis-dermis junction in the reconstructed skin.

专利号:US-5801192-A
优先权日:1995-08-25
标题 :Use of vitamin C or derivatives or analogues thereof promoting skin elastin synthesis
发明人：DUMAS MARC; BONTE FREDERIC; MEYBECK ALAIN; CHAUDAGNE CATHERINE
权利人:LVMH RECH
摘要:The invention relates to the use of ascorbic acid, notably L-ascorbic acid or vitamin C, or of its erythorbic acid isomer, or of their salts or esters, for promoting the synthesis of elastin in the dermis in the view of improving in particular skin elasticity. n The invention enables manufacturing cosmetic or pharmaceutical compositions, notably dermatological compositions, for improving skin elasticity, for example in the context of a product which improves skin tone or skin firmness. n The invention also enables increasing the elastin content of artificial dermes.

专利号:US-2004005342-A1
优先权日:2002-02-07
标题 :Topical administration of ascorbic acid to reinforce the cohesion of the dermo-epidermal junction
发明人：BERNERD FRANCOISE
权利人:OREAL
摘要:The present invention relates to the pharmaceutical or cosmetic use of a composition comprising, in a pharmaceutically or cosmetically acceptable medium, ascorbic acid or an analogue thereof to reinforce the cohesion of the dermo-epidermal junction. n The invention also relates to the pharmaceutical or cosmetic use of a composition comprising, in a pharmaceutically or cosmetically acceptable medium, ascorbic acid or an analogue thereof to increase the synthesis of tenascin and/or collagen VII. n The invention also relates to the use of ascorbic acid or of an analogue thereof to reinforce the cohesion of the dermo-epidermal junction of reconstructed skins.

专利号:US-10799441-B2
优先权日:2011-06-06
标题:Skin treatments containing pyrroloquinoline quinone (PQQ) esters and methods of preparation and use thereof
发明人：LEWIS II JOSEPH ABERNATHY; DINARDO JOSEPH C
权利人:LEWIS II JOSEPH ABERNATHY; DINARDO JOSEPH C; PCR TECH HOLDINGS LC
摘要:The present invention relates to cosmetic or dermatological compositions containing PQQ or its esters, methods of treating or promoting skin changes by topical application of these compositions, and methods of synthesis of PQQ esters. The PQQ ester-containing compositions of the present invention are unexpectedly effective in treating skin, particularly with respect to skin tolerance. When included in a topical composition, the PQQ esters of the present invention have an antioxidant effect that is useful in treating a skin change.

专利号:US-7087743-B2
优先权日:2000-02-11
标 题 :Oligonucleotides and use of oligonucleotides modulating the expression of enzymes involved in the synthesis of melanic pigments, as depigmentation agents
发明人：KURFURST ROBIN; JOLY REGINE
权利人:LVMH RECH
摘要:The present invention relates to novel oligonucleotide sequences and also to derivatives thereof. n These novel oligonucleotide sequences are capable of hybridizing specifically with the gene or with a product of the gene encoding tyrosinase, or with the gene or a product of the gene encoding tyrosinase-related-protein 1 (TRP-1). n The present invention also relates to the use of these novel oligonucleotide sequences as a depigmenting or bleaching agent in a cosmetic composition or in a dermatological composition.