CAS: 10351-88-9; (2S,3S)-(+)-1,4-Dimethoxy-2,3-Diveratrylbutane

该化合物是主要与药用植物Phyllanthus amarus隔离的生物活性离子体化合物,这种植物传统上用于草药治疗,具有显著的肝保护特性,在侧重于肝脏健康和脱毒途径的研究中具有宝贵价值.Pyllantin已证明具有作为抗氧化剂和抗炎剂的潜力,其研究表明其在调制脂类新陈代谢和减轻氧化压力方面的作用.其分子结构允许与生物目标有选择地互动,加强其药理学研究的效用.该化合物的特征是用于纯度评估的HPLC或LC-MS,确保研究应用的一致性.其稳定性和有据可查的机制有助于其在临床前的调查中的相关性.

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上下游产品

g-threo-2,3-bis-(3,4-dimethoxy-benzyl)-butanediol-(1,4)Dg-threo-2,3-bis-(3,4-dimethoxy-benzyl)-butanediol-(1,4) methyl iodide g-threo-2.3-bis-(3.4-dimethoxy-benzyl)-succinic acidDg-threo-2.3-bis-(3.4-dimethoxy-benzyl)-succinic acid D,L-2,3-bis(3,4-dimethoxybenzyl)succinic acidS:S)-1,4-dimethoxy-2,3-bis-(6-bromo-3,4-dimethoxy-benzyl)-butane(S:S)-1,4-dimethoxy-2,3-bis-(6-bromo-3,4-dimethoxy-benzyl)-butane 4-(3,4-Dimethoxy-phenyl)-6,7-dimethoxy-3-methoxymethyl-naphthalene-2-carbaldehyde 3,4,3',4'-tetramethoxy-9,9'-epoxylignan 1-(3,4-dimethoxy-phenyl)-6,7-dimethoxy-2,3-dimethyl-naphthalene

合成工艺路线路线简述

    📜D,L-2,3-Bis(3,4-Dimethoxybenzyl)Succinic Acid置于lithium Aluminium Tetrahydride,Silver(L) Oxide体系中,用 四氢呋喃,N,N-二甲基甲酰胺 用作溶剂,化学反应生成1,1'-[(2S,3S)-2,3-双(甲氧基甲基)-1,4-丁二基]双[3,4-二甲氧基苯]
    参考文献:Crystalline Constituents Of Euphorbiaceae-vi
    标题:Crystalline Constituents Of Euphorbiaceae-vi
    摘要:
    Doi:10.1016/s0040-4020(01)82594-1

    海关参考信息

    专利信息


    专利号:US-7829124-B2
    优先权日:2001-04-26
    标题:Use of Phyllanthus constituents for treating or preventing infections caused by hepatitis B-viruses
    发明人:OTT MICHAEL; MANNS MICHAEL P
    权利人:OTT MICHAEL; MANNS MICHAEL P
    摘要:The disclosure relates to a method of inhibiting synthesis of viral DNA in a mammal infected with a hepatitis B virus. This method includes administering at least one Phyllanthus component or substance to a mammal infected with the hepatitis B virus. It also includes inhibiting hepatitis B viral DNA synthesis in the mammal using the Phyllanthus component or substance. The disclosure also relates to a method of inhibiting viral gene expression in a mammal infected with a hepatitis B virus. This method includes administering at least one Phyllanthus component or substance to a mammal infected with the hepatitis B virus. It also includes inhibiting expression of at least one hepatitis B viral gene in the mammal using the Phyllanthus component or substance. These methods may form part of a method of preventing or treating hepatitis B infection.

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    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    合成参考文献


    参考文献:10.1021/np50124a006
    摘要:Hussain RA, Dickey JK, Rosser MP, Matson JA, Kozlowski MR, Brittain RJ, Webb ML, Rose PM, Fernandes P. A Novel Class of Non-Peptidic Endothelin Antagonists Isolated from the Medicinal Herb Phyllanthus niruri. J. Nat. Prod. 1995 Oct;58(10):1515–20. doi: 10.1021/np50124a006.
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