CAS: 93319-65-4; Pyridazin-3-Ylmethanamine

该化合物是一种有机化合物,其特征为:有六人组成的芳香环环,含有两个氮原子;该化合物的特征是附于的甲基胺组,有助于其基本性和潜在反应性;通常,3-丙烯基甲基胺的化合物具有极地溶剂溶解性等特性,因为有可溶解氢的铁矿功能组存在,这种物质可以进行氢结合;存在基胺会引发特定的生物活动,使其对医药化学和药物开发感兴趣;此外,由于该矿群的核循环性质,该化合物可能参与各种化学反应,包括通灵和细胞反应,其化学编号为93319-65-4,从而能够准确识别化学数据库和文献中的溶解特性;总体而言,三-丙基氮甲基胺是其潜在药物应用及其独特结构特征的一种化合物.

英文名称Pyridazin-3-Ylmethanamine
中文名称3-哒嗪甲胺
IUPAC名称pyridazin-3-ylmethanamine
其它别名3-甲胺哒嗪; 3-Pyridazinylmethylamine
CAS编号93319-65-4
MFCD编号:MFCD05664656
EINECS号:809-822-1
分子式:C5H7N3
分子量:109.13
产品CID: 1971444
产品分类有机原料→分子砌块→芳杂环类化合物→哒嗪类化合物

相似结构搜索
InChIKey: BCPGZEVUJXKIHK-UHFFFAOYSA-N
InChI=1S/C5H7N3/c6-4-5-2-1-3-7-8-5/h1-3H,4,6H2…
计算化学: 氢键受体数3.0氢键供体数1.0可旋转键数1.0

相似化合物

1337879-71-6 1228788-25-7 2375272-95-8

MSDS等安全信息

GHS象形图
GHS符号GHS06;
注释: Skull and crossbones
危险类别急性毒性类别4(吸入)
急性毒性类别4(经皮)
急性毒性类别4(经口)
特定目标器官毒性 - 单次接触类别3
皮肤腐蚀/刺激类别2
严重眼损伤类别1
急性毒性类别3(经口)
警示词Danger(危险)
危险描述H332 |吸入有害.
H312 |皮肤接触有害.
H302 |吞咽有害.
H335 |可能引起呼吸道刺激.
H315 |造成皮肤刺激.
H318 |造成严重眼损伤.
H301 |吞咽会中毒.
防范说明P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
危险品标志T
安全声明45
危险类别码25

欧盟法规

C&L通报

上下游产品

pyridazine-3-carbonitrile 3-methylpyridazine pyridazine-3-carbaldehyde oxime (Z)-2-{1-[2-chloro-4-(3-methyl-1H-pyrazol-1-yl)benzoyl]-4,4-difluoro-1,2,3,4-tetrahydro-5H-1-benzazepin-5-ylidene}-N-(pyridazin-3-ylmethyl)acetamide 7-[2-(5-methyl-1-phenyl-1H-benzimidazol-2-yl)ethyl]imidazo[1,5-b]pyridazine

合成工艺路线路线简述

52348-44-4 = 93319-65-4
反应条件:1.1 Reagents: Hydrogen Catalysts: Palladium Solvents: Ethanol; 1 H,Rt
标题:Synthesis And Structure-Activity Relationships Of Amide Derivatives Of (4,4-Difluoro-1,2,3,4-Tetrahydro-5H-1-Benzazepin-5-Ylidene)Acetic Acid As Selective Arginine Vasopressin V2 Receptor Agonists
作者:Tsukamoto,Issei; Koshio,Hiroyuki; Kuramochi,Takahiro; Saitoh,Chikashi; Yanai-Inamura,Hiroko; Et Al
参考文献:Bioorganic & Medicinal Chemistry 日期:2009 卷标:17(8) 页码:3130-3141]

53896-49-4 = 93319-65-4
反应条件:1.1 Reagents: Hydrogen,Ammonia Catalysts: Nickel Solvents: Methanol; 60 Psi,40 °C
标题:Preparation Of Arylsulfonyl-Substituted Indoles As Cb1 Receptor Modulators
参考文献:World Intellectual Property Organization]

= 93319-65-4 [标题:Reaction Conditions
标题:(Pyridylaminoalkylamino)Thiadiazoles As Histamine H1 Antagonists
参考文献:European Patent Organization]

1279818-63-1 = 93319-65-4
反应条件:1.1 Reagents: Hydrogen Catalysts: Palladium Solvents: Ethanol; Overnight,Rt
标题:Preparation Of Purinamine Compounds Treatment Of Neurodegenerative And Mitochondrial Disease
参考文献:World Intellectual Property Organization]

1072806-50-8 = 93319-65-4
反应条件:1.1 Reagents: Sodium Hydroxide Solvents: Water; 1 H,Reflux; Reflux -> Rt
标题:Heterocyclic Compounds As Stearoyl-Coa Desaturase Inhibitors And Their Preparation,Pharmaceutical Compositions And Use In The Treatment Of Diseases
参考文献:World Intellectual Property Organization]

= 93319-65-4 [标题:Reaction Conditions
标题:Preparation Of Indoylmethanamine Derivatives And Analogs For Use As Lysyl Oxidase-Like 2 Inhibitors
参考文献:World Intellectual Property Organization

3-甲基哒嗪以甲醇,Palladium On Charcoal 作为反应溶剂,以99%的收率获得产物3-哒嗪甲胺
参考文献:Histamine Antagonist Triadiazole Derivatives,Compositions,And Method
标题:Histamine Antagonist Triadiazole Derivatives,Compositions,And Method
摘要:新的3,4-二氨基-1,2,5-噻二唑氧化物衍生物,是组织胺h.Sub.1-拮抗剂.该发明的一种特定化合物是3-[3-[n-(4-氟苄基)-N-吡啶-2-基氨基]丙基氨基]-4-[嘧啶-4-基甲氨基]-1,2,5-噻二唑-1-氧化物.

专利信息

专利号:US-2025129021-A1
优先权日:2023-09-19
标题:Small molecule protein synthesis modulators
发明人：GYGI DAVID; BAHMANYAR SOGOLE SAMI; HAMANN LAWRENCE
权利人:INTERDICT BIO INC
摘要:The present disclosure provides compounds of the formulae herein (e.g., Formula (I), Formula (V)), and pharmaceutically acceptable salts thereof, which are useful for modulating protein synthesis (e.g., modulating synthesis of BCL-2, MYC, CCND1, MCL-1, ALK, KRAS-G12D). The present disclosure also provides pharmaceutical compositions and kits comprising the compounds, or pharmaceutically acceptable salts thereof, and methods of treating or preventing diseases or disorders (e.g., diseases or disorders associated with BCL-2, MYC, CCND1, MCL-1, ALK, KRAS-G12D) by administering to a subject in need thereof the compounds, or pharmaceutically acceptable salts thereof, or pharmaceutical compositions thereof.

专利号:DE-102011106849-A1
优先权日:2010-12-15
标题:Process for the synthesis of N-N linked and around the N-N bond of rotation-inhibited bis-N-heterocyclic carbenes and their use as ligands for metal complexes

专利号:US-10308615-B2
优先权日:2015-05-29
标题:Heterocyclic compounds as inhibitors of Vanin-1 enzyme
发明人：CASIMIRO-GARCIA AGUSTIN; CONDON JEFFREY SCOTT; FLICK ANDREW CHRISTOPHER; GOPALSAMY ARIAMALA; KIRINCICH STEVEN J; MATHIAS JOHN PAUL; STROBACH JOSEPH WALTER; XIANG JASON SHAOYUN; XING LI HUANG; WANG XIAOLUN
权利人:PFIZER
摘要:Compounds, pharmaceutically acceptable salts thereof, are disclosed wherein the compounds have the structure of n nas defined in the specification. Corresponding pharmaceutical compositions, methods of treatment, methods of synthesis, and intermediates are also disclosed.