CAS: 4919-37-3; 4-Hydroxy-3,5-Dimethylbenzoic Acid

上下游产品

CAS号124-38-9 二氧化碳 | CAS号10570-67-9 4-碘-2,6-二甲苯酚 | CAS号21553-46-8 3,5-二甲基-4-甲氧基苯甲酸 | CAS号97888-80-7 4-(苄氧基)-3,5-二甲基苯甲酸 | CAS号201230-82-2 carbon monoxide | CAS号4919-40-8 4-氨基-3,5-二甲基-苯甲酸 | CAS号576-26-1 2,6-二甲基苯酚 | CAS号80238-12-6 2,6-二甲基－对二苯甲酸 | CAS号2233-18-3 3,5-二甲基-4-羟基苯甲醛 | CAS号83037-98-3 3,5-DIMETHYL-4-... | CAS号100311-41-9 ethyl 3,5-dimet... | CAS号4397-14-2 4-(羟甲基)-2,6-二甲基苯酚 | CAS号576-26-1 2,6-二甲基苯酚 | CAS号124-38-9 二氧化碳 | CAS号2423-71-4 2,6-二甲基-4-硝基苯酚 | CAS号34137-14-9 4-羟基-3,5-二甲基苯甲酸甲酯 | CAS号25081-39-4 3,5-二甲基苯甲酸甲酯 | CAS号100347-72-6 ethyl 3,5-dimet... | CAS号7192-66-7 4-(Allyloxy)-N,... | CAS号42293-38-9 Benzoylchloride...

📜2,6-二甲基苯酚置于盐酸,Potassium Iodate,正丁基锂,Potassium Iodide体系中,用 四氢呋喃,甲醇,正己烷 作为反应溶剂,化学反应 2.83H,反应生成 4-羟基-3,5-二甲基苯甲酸
参考文献:Replacement Of The N-Terminal Tyrosine Residue In Opioid Peptides With 3-(2,6-Dimethyl-4-Carbamoylphenyl)Propanoic Acid (Dcp) Results In Novel Opioid Antagonists
标题:Replacement Of The N-Terminal Tyrosine Residue In Opioid Peptides With 3-(2,6-Dimethyl-4-Carbamoylphenyl)Propanoic Acid (Dcp) Results In Novel Opioid Antagonists
摘要:3-(2,6-Dimethyl-4-Carbamoylphenyl) Propanoic Acid (Dcp),A 2',6'-Dimethyltyrosine Analogue Containing A Carbamoyl Group In Place Of The Hydroxyl Function And Lacking The Amino Group,Was Synthesized. The Replacement Of Tyr(1) In An Enkephalin Analogue And In Dynorphin A(1-11)-Nh2 With Dcp Resulted In The First Opioid Peptide-Derived Antagonists That Do Not Contain A Phenolic Hydroxyl Group At The 1-Position Residue. The Cyclic Peptide Dcp-C[d-Cys-Gly-Phe(Pno(2))-D-Cys] Nh2 Represents A Novel,Potent Mu Opioid Antagonist.
DOI:10.1021/jm060369K

专利信息

专利号:US-9512080-B2
优先权日:2012-07-10
标 题:Synthesis of acridinium compounds by N-alkylation of acridans
发明人：NATRAJAN ANAND; WEN DAVID
权利人:SIEMENS HEALTHCARE DIAGNOSTICS INC
摘要:A method is provided for N-alkylation of acridine compounds by reduction of acridines to corresponding acridans to improve the reactivity of the acridine nitrogen, and subsequent N-alkylation of the acridans in ionic liquid solvents to provide the corresponding acridinium compounds in high yield. This inventive process improves chemical conversion, and does not require the use of highly toxic alkylating agents, such as 1,3-propane sultone.

专利号:US-5656426-A
优先权日:1988-08-01
标 题:Functionaized hydrophilic acridinium esters
发明人：LAW SAY-JONG; SOTIRIOU-LEVENTIS CHARIKLIA; NATRAJAN ANAND; JIANG QINGPING; CONNOLLY PETER B; KILROY JOHN P; MCCUDDEN CONSTANCE R; TIRRELL STEPHEN M
权利人:CHIRON DIAGNOSTICS CORP
摘要:Novel acridinium esters that are useful, either alone or when incorporated into liposomes, as chemiluminescent agents in binding assays (e.g., immunoassays and gene probe assays) with improved-sensitivity are disclosed. In addition, the synthesis of these esters and their use in assays for detecting an analyte is described. In particular, assays for testosterone and the Rubella virus are disclosed.

专利号:US-7629488-B2
优先权日:2005-03-14
标 题 :Process for the preparation of opioid modulators
发明人：CAI CHAOZHONG; HE WEI
权利人:JANSSEN PHARMACEUTICA NV
摘要:The present invention is directed to novel processes for the preparation of opioid modulators (agonists and antagonists) and intermediates in their synthesis. The opioid modulators are useful for the treatment and prevention of as pain and gastrointestinal disorders.

专利号:US-2015197491-A1
优先权日:2012-07-10
标 题:Synthesis of acridinium compounds by n-alkylation of acridans

专利号:US-5879894-A
优先权日:1993-03-19
标 题:Long emission wavelength chemiluminescent compounds and their use in test assays
发明人：LAW SAY-JONG; JIANG QINGPING; FISCHER WALTER; UNGER JOHN T; KRODEL ELIZABETH K; XI JUN
权利人:CHIRON DIAGNOSTICS CORP
摘要:An assay method incorporating at least two different chemiluminescent compounds for detection and/or quantitation of at least two substances in a test sample is described. The synthesis of chemiluminescent reagents or conjugates for use in such methods as well as kits incorporating such reagents are also disclosed. The assays have particular application in the field of clinical diagnostics.

专利号:EP-0617288-B1
优先权日:1993-03-19
标题 :Long emission wavelength chemiluminescent compounds and their use in test assays
发明人：LAW SAY-JONG; JIANG QINGPING; FISCHER WALTER; UNGER JOHN T; KRODEL ELIZABETH K
权利人:NOVARTIS AG; BAYER AG
摘要:An assay method incorporating at least two different chemiluminescent compounds for detection and/or quantitation of at least two substances in a test sample is described. The synthesis of chemiluminescent reagents or conjugates for use in such methods as well as kits incorporating such reagents are also disclosed. The assays have particular application in the field of clinical diagnostics.