CAS: 29421-92-9; 4-Bromo-2-Methylthiophene

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CAS号765-58-2 2-溴-5-甲基噻吩 | CAS号554-14-3 2-甲基噻吩 | CAS号41727-33-7 5-甲基-3-氰基噻吩 | CAS号221061-14-9 2-溴-5-甲基-3-噻吩羧酸 | CAS号88770-18-7 5-甲基噻吩-3-羧酸甲酯 | CAS号638-00-6 2,4-二甲基噻吩 | CAS号153137-85-0 5-甲基噻吩-3-胺 | CAS号172872-73-0 (4-溴-3,5-二甲基噻吩-... | CAS号19156-50-4 5-甲基噻吩-3-羧酸 | CAS号82834-44-4 3-bromo-5-methy... | CAS号86525-75-9 1-(tert-Butylam... | CAS号89556-02-5 3-bromo-5-methy...

📜2-甲基噻吩置于n-溴代丁二酰亚胺(Nbs),正丁基锂,高氯酸,二异丙胺体系中,用 四氢呋喃,N,N-二甲基甲酰胺 用作溶剂,化学反应 52.0H,反应生成4-溴-2-甲基噻吩
参考文献:用于水溶液和可聚焦光的光致变色化合物的合成
标题:用于水溶液和可聚焦光的光致变色化合物的合成
摘要:已制备并表征了在纯水中具有改进性能的光致变色化合物.它们具有不对称和扩展的共轭系统,具有 1,2-双(3-噻吩基)全氟环戊烯核心,与磺酸残基连接的额外噻吩环以及末端吡啶-4-基和 4-烷氧基苯基.已经开发了一种多步合成路线,以进一步衍生化所需的具有氨基的关键化合物.初始"开环"化合物的完全光环化反应(在甲醇或水中的最大吸收波长为 340 Nm)可以在纯水或缓冲水溶液(未添加有机溶剂)中在 366-375 的辐照下使用二极管激光器进行纳米,有色"闭环"化合物的反向开环反应(λmax = 628 或 624 Nm,在甲醇或水中)在可见绿光或红光(> 500 Nm)照射下发生.具有仲氨基的构件 57 可进一步用于合成具有重要意义的可逆可转换荧光化合物,其中荧光染料(供体)连接到光致变色单元(受体)上,并且共振能量从受体的有色形式的供体提供水溶液中荧光信号的可逆猝灭.
Doi:10.1002/ejoc.201100166

专利信息

专利号:US-7635781-B2
优先权日:2001-05-15
标 题:Synthesis of cyclopentadiene derivatives
发明人：NIFANT EV ILYA; KASHULIN IGOR; IVCHENKO PAVEL; KLUSENER PETER; KORNDORFFER FRANS; DE KLOE KEES; RIJSEMUS JOS
权利人:BASELL POLYOLEFINE GMBH
摘要:A compound of formula (X): n n n n n n n n n n n n wherein n R 1 , R 2 , equal to or different from each other are hydrogen or a linear or branched saturated or unsaturated C 1 -C 20 -alkyl, C 3 -C 20 -cycloalkyl, C 6 -C 20 -aryl, C 7 -C 20 -alkylaryl or C 7 -C 20 -arylalkyl radical, optionally containing heteroatoms belonging to groups 13-17 of the Periodic Table of the Elements; or they can form a C 4 -C 7 ring optionally containing O, S, N, P or Si atoms that can bear substituents; n R 3 is hydrogen or a linear or branched saturated or unsaturated C 1 -C 20 -alkyl, C 3 -C 20 -cycloalkyl, C 6 -C 20 -aryl, C 7 -C 20 -alkylaryl or C 7 -C 20 -arylalkyl radical, optionally containing heteroatoms belonging to groups 13-17 of the Periodic Table of the Elements; or two adjacent R 3 groups can form a C 4 -C 7 ring optionally containing O, S, N, P or Si atoms, wherein said ring can bear substituents; n and at least one of R 1 , R 2 or R 3 is different from hydrogen.

专利号:WO-2025128873-A1
优先权日:2023-12-12
标题:Heterocyclic pyridinone compounds as triggering receptor expressed on myeloid cells 2 agonists and methods of use
发明人：HOUZE JONATHAN B; PANDYA BHAUMIK
权利人:VIGIL NEUROSCIENCE INC
摘要:The present disclosure provides compounds of Formula (I), useful for the activation of Triggering Receptor Expressed on Myeloid Cells 2 ('TREM2'). This disclosure also provides pharmaceutical compositions comprising the compounds, uses of the compounds, and compositions for treatment of, for example, a neurodegenerative disorder. Further, the disclosure provides intermediates useful in the synthesis of compounds of Formula (I).

专利号:EP-1926738-B1
优先权日:2005-09-19
标题:Synthesis of cyclopentadienedithiophene derivatives
发明人：GUIDOTTI SIMONA
权利人:BASELL POLYOLEFINE GMBH
摘要:A process for preparing cyclopentadiene derivatives having formula (I) wherein T1 is selected from the group consisting of oxygen (O), or sulphur (S); R1, R2, R3 and R4, are hydrogen atoms, or hydrocarbon radicals; comprising the following steps: a) reacting a compound of formula (II) with a compound of formula (III) in the presence of a palladium or nickel based catalyst and a base; b) contacting the obtained compound with a carbonylating system; and c) treating the product obtained in step b) with a reducing agent.

专利号:US-7129361-B2
优先权日:1998-04-15
标 题 :Thienylazolylalkoxyethanamines, their preparation and their application as medicaments
发明人：MERCE-VIDAL RAMON; ANDALUZ-MATARO BLAS; FRIGOLA-CONSTANSA JORDI
权利人:ESTEVE LABOR DR
摘要:The thienylazolylalkoxyethanamines (I) where R1 is a hydrogen atom, a halogen atom or a lower alkyl radical; R2, R3 and R4 represent, independently, a hydrogen atom or a lower alkyl radical; and Az represents a five-member nitrogenated hetercyclic aromatic group, N-methyl-substituted, that contains from one to three nitrogen atoms. They have analgesic activity in mammals, including humans. The compounds (I) can be obtained, for example, by reaction of a derivative of hydroxy-thienylazol (IV) with a derivative of a suitable N-(ethyl)amine. The compounds (IV) are useful intermediates in the synthesis of the compounds (I). The compounds (I) have an application in human and/or veterinary medicine.

专利号:US-2008287692-A1
优先权日:2001-05-15
标 题:Synthesis of cyclopentadiene derivatives

专利号:US-2009118522-A1
优先权日:2005-09-19
标题 :Synthesis of Cyclopentadienedithiophene Derivatives