CAS: 270065-88-8; (S)-3-Amino-4-(4-Cyanophenyl)Butanoic Acid
该化合物是一种有机化合物,其特点是氨基酸结构,包括一种氰化苯的混合物.该化合物具有氨基组特征,表明丁亚酸链的碳存在一个氨基组(-NH2),在芳香环上存在一个阳性环上的一个西诺组(-CN),有助于其化学再活动及其在各个领域的潜在应用,包括制药和生物化学.该化合物的立体化学作用非常重要,因为(S)的指定表明在阳性中心周围的原子的具体空间安排可以影响其生物活动以及与其他分子的相互作用.一般而言,此类化合物可能具有诸如极地溶剂中的溶性,形成氢联结的潜力,以及与电益或核素的再活性,使其在合成有机化学化学和药化学研究中具有价值.
- 英文名称(S)-3-Amino-4-(4-Cyanophenyl)Butanoic Acid
- 中文名称(S)-3-氨基-4-(4-氰基苯基)丁酸
- 其它别名L-β-3-氨基-4-(4-氰基苯基)-丁酸.盐酸盐; (S)-3-Amino-4-(4-Cyano-Phenyl)-Butyric Acid-Hcl
- CAS编号270065-88-8
- MFCD编号:MFCD01861078
- 分子式:C11H12N2O2分子量:204.23
- 产品CID: 1249802
- 产品分类有机原料→分子砌块→芳环类化合物→苯类化合物
MSDS等安全信息
合成工艺路线路线简述
海关参考信息
- 2902600000-乙苯
2905121000-正丙醇
2905130000-正丁醇
2912110000-甲醛 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
专利信息
专利号:US-2022243244-A1
优先权日:2019-10-10
标 题 :Compositions and methods for in vivo synthesis of unnatural polypeptides
发明人：ROMESBERG FLOYD E; FISCHER EMIL C; HASHIMOTO KOJI; FELDMAN AARON W; DIEN VIVIAN T; ZHANG YORKE
权利人:SCRIPPS RESEARCH INST
摘要:Disclosed herein are compositions, methods, and kits for a cell incorporating unnatural amino acids into an unnatural polypeptide. Also disclosed herein are compositions, methods, and kits for increasing activity and yield of the unnatural polypeptide synthesized by the cell.
专利号:US-2023037284-A9
优先权日:2018-11-30
标题:Combination therapy of peptidomimetic macrocycles
发明人：GUERLAVAIS VINCENT; ANNIS DAVID ALLEN
权利人:AILERON THERAPEUTICS INC
摘要:The present disclosure describes the synthesis of peptidomimetic macrocycles and methods of using peptidomimetic macrocycles to treat a condition. The present disclosure also describes methods of using peptidomimetic macrocycles in combination with at least one additional pharmaceutically-active agent for the treatment of a condition, for example, cancer.
专利号:US-2025084410-A1
优先权日:2015-01-12
标 题:Incorporation of unnatural nucleotides and methods thereof
发明人：PTACIN JEROD; MALYSHEV DENIS A; CAFFARO CAROLINA E
权利人:SYNTHORX INC
摘要:Disclosed herein are methods, compositions and kits for the synthesis of proteins which comprises unnatural amino acids that utilize a mutant tRNA.
专利号:US-2018371021-A1
优先权日:2017-05-11
标 题 :Peptidomimetic macrocycles and uses thereof
发明人：AIVADO MANUEL; GUERLAVAIS VINCENT; OLSON KAREN
权利人:AILERON THERAPEUTICS INC
摘要:The present disclosure describes the synthesis of peptidomimetic macrocycles and methods of using peptidomimetic macrocycles to treat a condition. The present disclosure also describes methods of using peptidomimetic macrocycles in combination with at least one additional pharmaceutically-active agent for the treatment of a condition, for example, cancer.
专利号:WO-2021072167-A1
优先权日:2019-10-10
标 题:Compositions and methods for in vivo synthesis of unnatural polypeptides
专利号:US-11091522-B2
优先权日:2018-07-23
标题 :Peptidomimetic macrocycles and uses thereof
发明人：AIVADO MANUEL; GUERLAVAIS VINCENT; OLSON KAREN; ANNIS DAVID ALLEN
权利人:AILERON THERAPEUTICS INC
摘要:The present disclosure describes the synthesis of peptidomimetic macrocycles and methods of using peptidomimetic macrocycles to treat a condition. The present disclosure also describes methods of using peptidomimetic macrocycles in combination with at least one additional pharmaceutically-active agent for the treatment of a condition, for example, cancer.
