CAS: 117398-49-9; Fmoc-Ala-Oh-15N

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氯甲酸-9-芴基甲酯 (Fluorenylmethoxy)Carbonyl Chloride 28920-43-6

📜L-丙氨酸-15N,氯甲酸-9-芴基甲酯置于sodium Carbonate体系中,用 1,4-二氧六环,水 用作溶剂,化学反应生成N-芴甲氧羰基-15N丙氨酸
参考文献:Isobaric Stable Isotope-Containing Phosphorylated Protein Labeling Reagent,And Preparation Method And Application Thereof
标题:Isobaric Stable Isotope-Containing Phosphorylated Protein Labeling Reagent,And Preparation Method And Application Thereof
摘要:An Isobaric Stable Isotope-Containing Phosphorylated Protein Labeling Reagent,And A Preparation Method And Application Thereof Are Provided. The Protein Labeling Reagent Is A Phosphorylated Dipeptide Organophosphorus Reagent Labeled By A Stable Isotope Such As Deuterium-2,Carbon-13,Oxygen-18,Or Nitrogen-15. The Preparation Method Includes: (1) Preparation Of An Isobaric Stable Isotope-Containing Amino Acid With N-Terminal Protection,(2) Preparation Of An Isobaric Stable Isotope-Containing Amino Acid Activated Ester Fmoc/boc-R 1-Nhs With N-Terminal Protection,(3) Preparation Of An Isobaric Stable Isotope-Containing Dipeptide,(4) Preparation Of An Isobaric Stable Isotope-Containing Phosphite,(5) Preparation Of An Isobaric Stable Isotope-Containing Phosphite Dipeptide,And (6) Preparation Of A Stable Isotope-Labeled N-Phosphorylated Amino Acid Activated Ester. The Present Protein Labeling Reagent Can Realize The Quantitative Analysis Of Polypeptides,Standard Proteins,Proteins In Cells,And Proteins In Urine Samples And Blood Samples,And Has The Advantages Of Good Accuracy,High Sensitivity,No Interference Of Isotope Effect And Wide Applicability.