CAS: 88099-67-6; N,N-Dibenzyl-L-Serine Methyl Ester

该化合物是一种有机化合物,其结构特征包括含有两个附于氮原子的苯基组的精液衍生物,该化合物通常具有氨酸和酯的特性,例如由于溶液存在,具有极性,能够形成氢结,在有机溶剂中可能溶解,而其在水中的溶解性可能因具体情况而异.苯基组的存在可影响其反应性和稳定性,使其有可能成为有机合成或药物应用中的有用中间体.此外,L-serine成分的性能可能带来具体的生物活动,使这种化合物成为对药用化学的兴趣的化合物.

结构式图片

欧盟法规

ECHA物质C&L通报

上下游产品

CAS号5680-80-8 L-丝氨酸甲酯盐酸盐 | CAS号100-39-0 溴化苄 | CAS号186581-53-3 重氮甲烷 | CAS号2788-84-3 L-丝氨酸甲酯 | CAS号100-52-7 苯甲醛 | CAS号100-44-7 氯化苄 | CAS号2766-43-0 B°C-L-丝氨酸甲酯 | CAS号352530-50-8 N,N-二苄基-O-(叔丁基二...

合成工艺路线路线简述

  • 合成目标产物 N,N-Dibenzyl-L-Serine Methyl Ester 主要起始原料 L-Serine Methyl Ester Hydrochloride And Benzyl Bromide
  • (文献来源)合成步骤主要原料 L-Serine Methyl Ester Hydrochloride 和 Benzyl Bromide
📜氯化苄置于氢氧化钾体系中,用 乙醚,乙醇,氯仿,水 作为反应溶剂,化学反应 1.0H,反应生成 N,N-二苯甲基-L-丝氨酸甲酯
参考文献:Gani,David; Hitchcock,Peter B.; Young,Douglas W.,Journal Of The Chemical Society. Perkin Transactions I,1985,P. 1363-1372
标题:Gani,David; Hitchcock,Peter B.; Young,Douglas W.,Journal Of The Chemical Society. Perkin Transactions I,1985,P. 1363-1372

海关参考信息

专利信息


专利号:US-8026384-B2
优先权日:2007-05-04
标题:Process for the synthesis of alkyl phosphinic acids by initiation of an amine and an amineoxide
发明人:FINNHULT DANIEL; SOHLBERG ROGER; STALFORS FREDRIK; SVENSSON CARINA; WACHTMEISTER JOHANNA; WANNMAN THOMAS
权利人:ASTRAZENECA AB
摘要:The present invention relates to a new process for the synthesis of alkyl phosphinic acids, and more particularly to a coupling reaction between an alkylhalide and a hypophosphorous acid derivative in the presence of an amine and an amineoxide.

专利号:US-7598403-B2
优先权日:2003-05-16
标 题 :Synthesis of chromanones
发明人:SALVATORE BRIAN A; SOLIS FERDINAND C
权利人:UNIV SOUTH CAROLINA RES FOUND
摘要:Processes for the preparation of biologically active chromanones are disclosed, including processes for the preparation of intermediates useful in the preparation of the biologically active chromanones. The chromanones and the intermediates disclosed herein may be useful for a variety of therapies, including the treatment of various cancers and the treatment of inflammation and inflammation related disorders.

专利号:US-2010130773-A1
优先权日:2007-05-04
标题 :Process for the synthesis of alkyl phosphinic acids by initiation of an amine and an amineoxide

专利号:EP-2155762-B1
优先权日:2007-05-04
标 题 :Process for the synthesis of alkyl phosphinic acids by initiation of an amine and an amineoxide

专利号:US-2007203214-A1
优先权日:2003-05-16
标 题 :Synthesis Of Chromanones

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品牌试剂参考报价(招募中)

📌 第三方产品分析报告

✅ COA系统入驻 | 共享模式

合成参考文献


参考文献:10.1007/s11426-010-0026-y
摘要:Ai T, Pindi S, Kattamuri PV, Li G. Chiral N-phosphonyl imine chemistry: asymmetric additions of glycine enolate to diphenyl diamine-based phosphonyl imines. Science China Chemistry. 2010 Jan;53(1):125–9. doi: 10.1007/s11426-010-0026-y.
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