CAS: 85523-00-8; N-Isopropyl-N-Methyl-Tert-Butylamine

该化合物是第三级的矿物质化合物,其特点是其分支烷基结构,这给其消毒障碍和影响反应力,该化合物主要用作有机合成的基础或催化剂,特别是用于需要选择性脱氧或非核生殖基的反应,其严重妨碍自然作用可最大限度地减少不想要的副作用,提高反应效率和产量.该化合物在各种条件下的稳定性使其适合用于敏感的合成工艺.此外,其低核分子性在必须避免干扰电动中心的应用中是有利的.由于它具有很强的酸或氧化剂的再活动潜力,适当的处理和储存是必不可少的.

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CAS号50-00-0 甲醛 | CAS号7515-80-2 N-叔丁基异丙胺

合成工艺路线路线简述

  • 合成目标产物 N-Isopropyl-N-Methyl-Tert-Butylamine 主要起始原料 Formaldehyde And N-Tert-Butylisopropylamine
  • 7515-80-2 = 85523-00-8
    反应条件:1.1 Reagents: Formic Acid Solvents: Water; 0 °C; 2 H,50 - 55 °C1.2 Reagents: Potassium Hydroxide Solvents: Water
    标题:Molecular Addition Compounds. 15. Synthesis,Hydroboration,And Reduction Studies Of New,Highly Reactive Tert-Butyldialkylamine-Borane Adducts
    作者:Brown,Herbert C.; Et Al
    参考文献:Journal Of Organic Chemistry 日期:1999 卷标:64(17) 页码:6263-6274]

    7515-80-2 = 85523-00-8 + 100-51-6
    反应条件:1.1 Reagents: Formic Acid Solvents: Water; 0 °C; 2 H,50 - 55 °C1.2 Reagents: Potassium Hydroxide Solvents: Water2.1 Reagents: (T-4)-Trihydro(Tetrahydrofuran)Boron Solvents: Tetrahydrofuran; Overnight,Rt3.1 Solvents: Tetrahydrofuran; 2 H,Rt3.2 Reagents: Water; Rt
    标题:Molecular Addition Compounds. 15. Synthesis,Hydroboration,And Reduction Studies Of New,Highly Reactive Tert-Butyldialkylamine-Borane Adducts
    作者:Brown,Herbert C.; Et Al
    参考文献:Journal Of Organic Chemistry 日期:1999 卷标:64(17) 页码:6263-6274]

    75-64-9 + 2973-10-6 = 85523-00-8 + 100-51-6
    反应条件:1.1 1 H,Reflux; Reflux -> 83 °C1.2 Reagents: Potassium Hydroxide Solvents: Water2.1 Reagents: Formic Acid Solvents: Water; 0 °C; 2 H,50 - 55 °C2.2 Reagents: Potassium Hydroxide Solvents: Water3.1 Reagents: (T-4)-Trihydro(Tetrahydrofuran)Boron Solvents: Tetrahydrofuran; Overnight,Rt4.1 Solvents: Tetrahydrofuran; 2 H,Rt4.2 Reagents: Water; Rt
    标题:Molecular Addition Compounds. 15. Synthesis,Hydroboration,And Reduction Studies Of New,Highly Reactive Tert-Butyldialkylamine-Borane Adducts
    作者:Brown,Herbert C.; Et Al
    参考文献:Journal Of Organic Chemistry 日期:1999 卷标:64(17) 页码:6263-6274]

    75-64-9 + 2973-10-6 = 85523-00-8
    反应条件:1.1 1 H,Reflux; Reflux -> 83 °C1.2 Reagents: Potassium Hydroxide Solvents: Water2.1 Reagents: Formic Acid Solvents: Water; 0 °C; 2 H,50 - 55 °C2.2 Reagents: Potassium Hydroxide Solvents: Water
    标题:Molecular Addition Compounds. 15. Synthesis,Hydroboration,And Reduction Studies Of New,Highly Reactive Tert-Butyldialkylamine-Borane Adducts
    作者:Brown,Herbert C.; Et Al
    参考文献:Journal Of Organic Chemistry 日期:1999 卷标:64(17) 页码:6263-6274]

    75-64-9 = 85523-00-8
    反应条件:1.1 Reagents: Adiponitrile Catalysts: Tetrabutylammonium Iodide; 30 Min,Reflux; Reflux -> 78 °C1.2 Reagents: Potassium Hydroxide Solvents: Water2.1 Reagents: Formic Acid Solvents: Water; 0 °C; 2 H,50 - 55 °C2.2 Reagents: Potassium Hydroxide Solvents: Water
    标题:Molecular Addition Compounds. 15. Synthesis,Hydroboration,And Reduction Studies Of New,Highly Reactive Tert-Butyldialkylamine-Borane Adducts
    作者:Brown,Herbert C.; Et Al
    参考文献:Journal Of Organic Chemistry 日期:1999 卷标:64(17) 页码:6263-6274]

    100-52-7 = 85523-00-8 + 100-51-6
    反应条件:1.1 Solvents: Tetrahydrofuran; 2 H,Rt1.2 Reagents: Water; Rt
    标题:Molecular Addition Compounds. 15. Synthesis,Hydroboration,And Reduction Studies Of New,Highly Reactive Tert-Butyldialkylamine-Borane Adducts
    作者:Brown,Herbert C.; Et Al
    参考文献:Journal Of Organic Chemistry 日期:1999 卷标:64(17) 页码:6263-6274]

    85523-00-8 = 85523-00-8 + 100-51-6
    反应条件:1.1 Reagents: (T-4)-Trihydro(Tetrahydrofuran)Boron Solvents: Tetrahydrofuran; Overnight,Rt2.1 Solvents: Tetrahydrofuran; 2 H,Rt2.2 Reagents: Water; Rt
    标题:Molecular Addition Compounds. 15. Synthesis,Hydroboration,And Reduction Studies Of New,Highly Reactive Tert-Butyldialkylamine-Borane Adducts
    作者:Brown,Herbert C.; Et Al
    参考文献:Journal Of Organic Chemistry 日期:1999 卷标:64(17) 页码:6263-6274]

    75-64-9 = 85523-00-8 + 100-51-6
    反应条件:1.1 Reagents: Adiponitrile Catalysts: Tetrabutylammonium Iodide; 30 Min,Reflux; Reflux -> 78 °C1.2 Reagents: Potassium Hydroxide Solvents: Water2.1 Reagents: Formic Acid Solvents: Water; 0 °C; 2 H,50 - 55 °C2.2 Reagents: Potassium Hydroxide Solvents: Water3.1 Reagents: (T-4)-Trihydro(Tetrahydrofuran)Boron Solvents: Tetrahydrofuran; Overnight,Rt4.1 Solvents: Tetrahydrofuran; 2 H,Rt4.2 Reagents: Water; Rt
    标题:Molecular Addition Compounds. 15. Synthesis,Hydroboration,And Reduction Studies Of New,Highly Reactive Tert-Butyldialkylamine-Borane Adducts
    作者:Brown,Herbert C.; Et Al
    参考文献:Journal Of Organic Chemistry 日期:1999 卷标:64(17) 页码:6263-6274
📜N-叔丁基异丙醇胺,Alkaline Earth Salt Of/the/ Methylsulfuric Acid 反应生成 N-异丙基-N-甲基叔丁胺
参考文献:金鸡纳生物碱介导的环状介孔酸酐的实用且高度对映选择性的开环.
标题:金鸡纳生物碱介导的环状介孔酸酐的实用且高度对映选择性的开环.
摘要:描述了在甲醇存在下金鸡纳生物碱介导的前手性环酐的打开,导致旋光性半酯.结构非常不同的酸酐被转化为其相应的甲基单酯,通过使用奎宁或奎尼丁作为直接添加剂,可以以高达99%ee的形式获得任何一种对映体.反应后,几乎可以定量回收生物碱并重新使用,而不会损失对映选择性.另外,提出了一种催化方案,该方案允许在容易获得的五甲基哌啶(哌啶)存在下亚化学计量使用奎尼丁.
DOI:10.1021/jo000638T

海关参考信息

专利信息


专利号:US-9951096-B2
优先权日:2008-08-22
标 题 :Catalysts and methods for polymer synthesis
发明人：ALLEN SCOTT D; CHERIAN ANNA E; SIMONEAU CHRIS A; FARMER JAY J; COATES GEOFFREY W; GRIDNEV ALEXEI; LAPOINTE ROBERT E
权利人:SAUDI ARAMCO TECH CO
摘要:The present invention provides unimolecular metal complexes having increased activity in the copolymerization of carbon dioxide and epoxides. Also provided are methods of using such metal complexes in the synthesis of polymers. According to one aspect, the present invention provides metal complexes comprising an activating species with co-catalytic activity tethered to a multidentate ligand that is coordinated to the active metal center of the complex.

专利号:US-9856349-B2
优先权日:2010-09-14
标 题:Catalysts and methods for polymer synthesis
发明人：FARMER JAY J
权利人:SAUDI ARAMCO TECH CO
摘要:The present invention provides bimetallic complexes having increased activity in the copolymerization of carbon dioxide and epoxides. Also provided are methods of using such metal complexes in the synthesis of polymers. According to one aspect, the present invention provides metal complexes comprising an activating species with co-catalytic activity tethered to a multidentate ligand that is coordinated to one or more active metal centers of the complex.

专利号:US-11185853-B2
优先权日:2017-12-22
标题 :Catalysts for polycarbonate production
发明人：ALLEN SCOTT D
权利人:SAUDI ARAMCO TECH CO
摘要:The present invention provides unimolecular metal complexes having increased activity in the copolymerization of carbon dioxide and epoxides. Also provided are methods of using such metal complexes in the synthesis of polymers. According to one aspect, the present invention provides metal complexes comprising an activating species with catalytic activity tethered to a ligand that is coordinated to the active metal center of the complex.

专利号:US-9394326-B2
优先权日:2011-08-08
标 题:Catalysts and methods for polymer synthesis
发明人：FARMER JAY J
权利人:FARMER JAY J; NOVOMER INC
摘要:The present invention provides oligomeric metal complexes having more than one metal center and methods of using such complexes. The provided metal complexes are useful in the copolymerization of carbon dioxide and epoxides.

专利号:CN-107531737-A
优先权日:2015-03-25
标 题:Synthesis of deoxyglycosamine

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摘要:Tian, T.; Li, Z., Science of Synthesis Knowledge Updates, (2020) 2, 376.
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