CAS: 7428-99-1; 2-(4-Methoxyphenyl)Propan-2-Ol

上下游产品

methyl magnesium iodide ethyl 4-methoxybenzoate 1-bromo-4-methoxy-benzene acetone 1-isopropenyl-4-methoxybenzene 4-(1-hydroxy-1-methylethyl)-1-methoxy-1,4-cyclohexadiene 1-(2-chloropropan-2-yl)-4-methoxybenzene 1-methoxy-4-(1-methylethyl)benzene

1-异丙烯基-4-甲氧基苯置于硫酸体系中,用 甲醇 作为反应溶剂,化学反应生成 2-(4-甲氧基苯基)丙-2-醇
参考文献:Kinetics And Mechanism Of Acid Catalysed Hydration Of α-Methylstyrenes
标题:Kinetics And Mechanism Of Acid Catalysed Hydration Of α-Methylstyrenes
摘要:十二种带有取代基h,Ch3,Cf3,Ch3O,Ch3S,F,Cl,Br,Ch3Co,Ch3So2,Cn和no2的α-甲基苯乙烯被合成;此外,在浓度范围从0.017到9.58摩尔/升的硫酸中,测量了这些化合物的酸催化水合动力学.所得到的观察速率常数被用来构建动力学酸度函数并计算催化速率常数.通过评估酸性函数动力学对酸性介质浓度的依赖性,以及α-甲基苯乙烯的酸催化水合反应的取代基效应对催化速率常数的影响,验证了酸催化水合的机理.该机理涉及在速率限制的反应步骤中向α-甲基苯乙烯的双键加入质子,被标记为a-Se2.在酸性介质对苯乙烯和α-甲基苯乙烯的酸催化水合的影响之间没有明显差异,这表明反应物和两种底物的过渡态的活性系数非常相似.取代基效应评估显示,反应的速率限制步骤在向底物加入质子时发生.与叔丁基氯化物水解形成的碳正离子相比,该反应步骤的过渡态中的碳正离子形成大致进行了一半.所得到的碳正离子特别受到具有+m效应的取代基的稳定作用,而具有-M和i效应的取代基的影响则明显较小.
DOI:10.1135/cccc20071025

专利信息

专利号:US-8258322-B2
优先权日:2008-08-28
标 题:Synthesis of hexahydrodibenzopyranones
发明人：MIKAYLO VALERIY; PARAMANANTHAM SUBAKAR; AVRUTOV ILYA; BROWN MARTYN A; LI ZEMIN; LAZAROWYCH NATALIE
权利人:MIKAYLO VALERIY; PARAMANANTHAM SUBAKAR; AVRUTOV ILYA; BROWN MARTYN A; LI ZEMIN; LAZAROWYCH NATALIE; WATSON LAB INC
摘要:An improved process is provided for the synthesis of hexahydrodibenzo[b,d]pyran-9-ones, such as nabilone.

专利号:WO-9805691-A1
优先权日:1996-08-07
标 题:Star polymers having multiple polyisobutylene arms emanating from a calixarene core and the synthesis thereof
发明人：KENNEDY JOSEPH P; MAJOROS ISTVAN J; JACOB SUNNY
权利人:UNIV AKRON
摘要:The synthesis and characterization of novel linear polymers and multi-arm star polymers comprising polyisobutylene arms connected to a well-defined calixarene core are described. The synthesis has been achieved using the 'core first' method wherein multifunctional calix[n]arene (where n=4 to 16) derivatives or their monofunctional analogues are used as initiators which, in conjunction with certain Freidel-Crafts acids as co-initiators, induce the living polymerization of isobutylene or a similar carbocationic polymerizable monomer to form star polymers or block copolymers. Novel initiators suitable for inducing the polymerization are also described.

专利号:US-5804664-A
优先权日:1997-05-23
标 题 :Star polymers having multiple arms emanating from a calixarene core, initiators therefor, and method for the synthesis thereof
发明人：KENNEDY JOSEPH P; MAJOROS ISTVAN J; JACOB SUNNY
摘要:The synthesis and characterization of novel linear polymers and multi-arm star polymers comprising polyisobutylene arms connected to a well-defined calixarene core are described. The synthesis has been achieved using the 'core first' method wherein multifunctional calix[n]arene (where n=4 to 16) derivatives or their monofunctional analogues are used as initiators which, in conjunction with certain Freidel-Crafts acids as co-initiators, induce the living polymerization of isobutylene or a similar carbocationic polymerizable monomer to form star polymers or block copolymers. Novel initiators suitable for inducing the polymerization are also described.

专利号:US-5844056-A
优先权日:1996-08-07
标题:Star polymers having multiple polyisobutylene arms emanating from a calixarene core, initiators therefor, and method for the synthesis thereof
发明人：KENNEDY JOSEPH P; MAJOROS ISTVAN J; JACOB SUNNY
权利人:UNIV AKRON
摘要:The synthesis and characterization of novel linear polymers and multi-arm star polymers comprising polyisobutylene arms connected to a well-defined calixarene core are described. The polymers are directly telechelic. They synthesis has been achieved using the 'core first' method wherein multifunctional calix n!arene (where n=4 to 16) derivatives or their monofunctional analogues are used as initiators which, in conjunction with certain Freidel-Crafts acids as co-initiators, induce the living polymerization of isobutylene or a similar carbocationic polymerizable monomer. Novel initiators suitable for inducing the polymerization are also described.

专利号:US-2010056811-A1
优先权日:2008-08-28
标 题:Synthesis of Hexahydrodibenzopyranones

专利号:US-4140701-A
优先权日:1976-07-06
标题:2,6-Methano-2H-1-benzoxocins
发明人：RYAN CHARLES W
权利人:LILLY CO ELI
摘要:Novel 2-oxy-5-isopropylidene-7-hydroxy-9-substituted-2,6-methano-3,4,5,6-tetrahydro-2H-1-benzoxocins are prepared by condensing a 5-(substituted)resorcinol with a 1-alkoxy-4-(1-hydroxy-1-methylethyl)-1,4-cyclohexadiene in the presence of a suitable catalyst. The new benzoxocin derivatives are useful in the synthesis of certain dibenzo[b,d]pyran-9-ones, valuable as anti-anxiety, analgesic, and anti-depressant drugs.