📜4-氯-6-甲基-1,3-苯二胺 反应生成 2,4,5-三氯甲苯 参考文献:Functional School Refusal Subtypes: Anxiety,Avoidance,And Malingering 标题:Functional School Refusal Subtypes: Anxiety,Avoidance,And Malingering 摘要:Chronic School Refusal Has Traditionally Been Classified Under Broad Categories Such As School Phobia And Truancy. However,The Need For Improved Recognition And Treatment Of School Refusal Has Heightened Efforts To Identify Subtypes Of School Refusal Behavior. Recent Efforts Have Focused On Functional Subtypes Of School Refusal. This Article Purposes To Extend Recent Efforts By Showing That The Three Basic Subtypes Of Anxiety,Avoidance,And Malingering Are Not Only Functional,Bur Consistent With Refusal Characteristics,Empirical Evidence From Factor Analysis And Clinical Diagnosis Over The Past Decade,And Treatment Approaches. Such Extension Is Intended To Aid Practitioners In Further Understanding And Using Functional Subtypes. (C) 2000 John Wiley & Sons,Inc. DOI:10.1002/(Sici)1520-6807(200003)37:2<183::Aid-Pits9>3.0.Co;2-5
专利号:WO-2012041858-A1 优先权日:2010-09-30 标 题:A process for the synthesis of thio-triazolo-group containing compounds
专利号:EP-2621922-A1 优先权日:2010-09-30 标 题:A process for the synthesis of thio-triazolo-group containing compounds
专利号:CN-104540803-B 优先权日:2012-08-13 标题 :Synthesis intermediate of 1- (2-deoxy-2-fluoro-4-thio- β -D-arabinofuranosyl) cytosine, synthesis intermediate of thionucleoside, and processes for producing these
专利号:US-7294732-B2 优先权日:2002-08-07 标 题:Silicon compound 发明人:OHNO KOHJI; TSUJII YOSHINOBU; FUKUDA TAKESHI 权利人:CHISSO CORP 摘要:A silicon compound represented by Formula (1). In Formula (1), R 1 is a group independently selected respectively from the group consisting of a hydrogen atom, alkyl, substituted or non-substituted aryl and substituted or non-substituted arylalkyl, and A 1 is an organic group substituted with a halogenated sulfonyl group and is preferably a group represented by Formula (2). In Formula (2), X is halogen; R 2 is alkyl; a is an integer of 0 to 2; and Z 1 is a single bond or alkylene having a carbon number of 1 to 10. n n n n n n n n n n The silicon compound provided by the present invention is a silsesquioxane derivative having an excellent living polymerizable radical polymerization initiating function. For example, it is possible to commence polymerization by allowing an acryl base monomer to coexist to form an acryl base polymer making use of one point of the structure of the silsesquioxane in the present invention as a starting point. Because a halogenated sulfonyl group has a strong electrophilicity, it is possible to synthesize various silsesquioxane derivatives by reacting the silicon compound provided by the present invention with various nucleophilic reagents, and it can actively be used as an intermediate useful for organic synthesis.
专利号:US-6936477-B2 优先权日:1994-04-13 标题 :Complex combinatorial chemical libraries encoded with tags 发明人:STILL W CLARK; OHLMEYER MICHAEL H J; DILLARD LAWRENCE W; READER JOHN C; WIGLER MICHAEL H 权利人:COLD SPRING HARBOR LAB 摘要:Encoded combinatorial chemistry is provided, where sequential synthetic schemes are recorded using organic molecules, which define choice of reactant, and stage, as the same or different bit of information. Various products can be produced in the multi-stage synthesis, such as oligomers and synthetic non-repetitive organic molecules. Conveniently, nested families of compounds can be employed as identifiers, where number and/or position of a substituent define the choice. Alternatively, detectable functionalities may be employed, such as radioisotopes, fluorescers, halogens, and the like, where presence and ratios of two different groups can be used to define stage or choice. Particularly, pluralities of identifiers may be used to provide a binary or higher code, so as to define a plurality of choices with only a few detachable tags. The particles may be screened for a characteristic of interest, particularly binding affinity, where the products may be detachable from the particle or retained on the particle. The reaction history of the particles which are positive for the characteristic can be determined by the release of the tags and analysis to define the reaction history of the particle.
参考文献:10.1016/s0045-6535(01)00289-2 摘要:Kato Y, Kimura R. The contribution of 2,3,5-trichlorophenyl methyl sulfone, a metabolite of 1,2,4-trichlorobenzene, to the delta-aminolevulinic acid synthetase induction by 1,2,4-trichlorobenzene in rat liver. Chemosphere. 2002 Apr;47(1):1–7. doi: 10.1016/s0045-6535(01)00289-2.