CAS: 50906-77-9; 3,3'-Disulfanediyldi(Propanehydrazide)

相似化合物

1002-19-3 6292-68-8 689-02-1

3,3'-二氢氧啉酸置于乙醇,硫酸,一水合肼体系中,化学反应生成 3,3'-二硫代二(丙酰肼)
参考文献:Seyden-Penne,Annales De Chimie (Cachan,France),1958,Vol. <13>3,P. 599,631
标题:Seyden-Penne,Annales De Chimie (Cachan,France),1958,Vol. <13>3,P. 599,631

专利信息

专利号:US-2015182634-A1
优先权日:2012-12-28
标 题:Molecular Design and Chemical Synthesis of Pharmaceutical-Ligands and Pharmaceutical-Pharmaceutical Analogs with Multiple Mechanisms of Action
发明人：COYNE CODY P; BEAR RYAN; JONES TONI
权利人:COYNE CODY P; BEAR RYAN; JONES TONI
摘要:Multi-phase and single-phase chemical reaction schemes have been developed for the synthesis of pharmaceutical-ligand analogs, pharmaceutical-pharmaceutical analogs, and similar molecular-molecular analogs that possess multiple mechanisms of action. The multi-phase organic chemical reaction schemes include relatively mild reaction conditions, high end product yields, and comparatively rapid completion of chemical reactions, which are all of particular utility for the synthesis of preparations including covalent pharmaceutical-receptor ligand or pharmaceutical-immunoglobulin analogs. Examples of pharmaceutical-ligand preparations that can be synthesized utilizing the multi-step chemical reaction schemes include covalent chemotherapeutic-ligand agents that possess selective targeted delivery properties and a capacity to exert additive and synergistic levels of cytotoxic anti-neoplastic potency. Pharmaceutical-pharmaceutical analogs, including chemotherapeutic-chemotherapeutic analogs that are capable of exerting multiple mechanisms of action, can be synthesized using either of the described multi-phase or single-phase organic chemistry reaction schemes. Each of these representative examples has utility against a spectrum of disease states including, for example, neoplastic conditions such as mammary adenocarcinoma/carcinoma, ovarian carcinoma, prostatic carcinoma, intestinal carcinoma, melanoma, leukemia, myeloma, and lymphoma.

专利号:US-8691793-B2
优先权日:2003-12-04
标题 :Modified macromolecules and associated methods of synthesis and use
发明人：PRESTWICH GLENN D; SHU XIAO ZHENG; LIU YANCHUN
权利人:PRESTWICH GLENN D; SHU XIAO ZHENG; LIU YANCHUN; UNIV UTAH RES FOUND
摘要:Described herein are compounds such as macromolecules that have been modified in order to facilitate crosslinking and methods of making and using thereof.

专利号:US-2008025950-A1
优先权日:2003-12-04
标 题:Modified Macromolescules and Associated Methods of Synthesis and Use

专利号:US-7981871-B2
优先权日:2003-12-04
标 题 :Modified macromolescules and associated methods of synthesis and use

专利号:US-2012142907-A1
优先权日:2003-12-04
标 题 :Modified macromolecules and associated methods of synthesis and use