CAS: 487-54-7; 2-(2-Hydroxybenzamido)Acetic Acid

该化合物是一种有机化合物,是硅酸的衍生物,其特征是其结构,包括硅酸碱和尿素组.该化合物一般是白色的脱白晶状固体,在水中可溶解,反映其极性,因为存在氢氧基和amin功能组,盐酸因其在盐酸药物(如阿司匹林)代谢中所起的作用而闻名,并经常研究其潜在的生物活动,包括反氟特性,其合成可能涉及硫酸与尿素或相关化合物的反应.在安全方面,与许多有机化合物一样,应谨慎处理,因为它对人类健康和环境的影响仍在研究中.总的来说,盐酸在制药化学和代谢研究中都是一种重要的化合物.

结构式图片

欧盟法规

ECHA物质C&L通报REACH预注册

上下游产品

CAS号178633-73-3 benzyl 2-(2-hyd... | CAS号55493-89-5 N-(2-Hydroxyben... | CAS号69-72-7 水杨酸 | CAS号579-75-9 邻甲氧基苯甲酸 | CAS号856119-90-9 2-azidoacetoxy-... | CAS号56145-98-3 N-(2-amino-2-ox... | CAS号14216-34-3 Benzoic acid,2-... | CAS号118-58-1 柳酸苄酯 | CAS号27796-49-2 N-(2-Methoxyben... | CAS号136492-94-9 Acetic acid,hyd... | CAS号65-45-2 水杨酰胺 | CAS号118-79-6 三溴苯酚 | CAS号56-40-6 甘氨酸 | CAS号69-72-7 水杨酸 | CAS号55493-89-5 N-(2-Hydroxyben...

合成工艺路线路线简述

  • 合成目标产物 Salicyluric Acid 主要起始原料 Glycine And Salicyloyl Chloride
  • (文献来源)合成步骤主要原料 Glycine 和 Salicyloyl Chloride
📜柳酸苄酯置于吡啶,Palladium On Activated Charcoal,乙二醇甲醚体系中,化学反应生成 2-羟基马尿酸
参考文献:氨基酰胆碱.2. Mitteilung.bildung Vonsalicoyl-Aminosäurenaus O-(cbzo-α-Aminoacyl)-Salicylsäuren
标题:氨基酰胆碱.2. Mitteilung.bildung Vonsalicoyl-Aminosäurenaus O-(cbzo-α-Aminoacyl)-Salicylsäuren
摘要:水杨基水杨基中的邻苯二甲氧基邻苯二甲氧基羰基-α-氨酰基)-水杨基苯胺基苯.在zimmertemperatur的中性染料oder Schwach Saurerlösung(methylcellosolve,Eisessig)中死于einlagerung Erfolgt.
DOI:10.1002/hlca.19570400644

海关参考信息

专利信息


专利号:US-2004110228-A1
优先权日:2002-04-01
标 题:Combinatorial organic synthesis of unique biologically active compounds
发明人:MCALPINE SHELLI R; TAYLOR RACHEL E; BOLLA MEGAN L; SEGALL ANCA M
摘要:The invention provides a method for making a combinatorial library of cyclic compounds, such as Holliday junction-trapping compounds, comprising the steps of (a) obtaining a plurality of trimers according to the generic structure X 1- X 2- X 3 , wherein X 1 , X 2 and X 3 can be independently any naturally or nonnaturally occurring amino acids or peptidomimetics thereof; (b) optionally coupling a spacer S to the trimer at either end; (c) cyclizing two trimers or trimer-spacer conjugates in a head-to-tail orientation; thereby obtaining a combinatorial library of compounds, wherein the library does not include an unmodifed or naturally occurring Holliday Junction-trapping compounds. The invention additionally provides methods macrocyclic compounds that are synergimycin derivatives.

专利号:US-2003199558-A1
优先权日:2001-12-28
标 题:Hydroxamic acid and its derivatives as inhibitors of melanocyte tyrosinase for topical skin lighteners
发明人:DOOLEY THOMAS P; CHENG LIN
权利人:INTEGRIDERM INC
摘要:Methods, compounds, and formulations are provided to reduce pigmentation in mammalian skin, comprising hydroxamic acid and its derivatives, and especially benzohydroxamic acid and its derivatives. The compounds preferably inhibit pigment synthesis in melanocytes through inhibition of melanocyte tyrosinase. The methods can be used for lightening skin, and for treating uneven skin complexions, which result from hyperpigmentation-related medical conditions such as melasma, age spots, freckles, ochronosis, and lentigo. The compounds can be used medically or cosmetically, and preferably as topical formulations.

专利号:US-2024400861-A1
优先权日:2021-10-01
标题 :Triazole- And/Or Triazolium-Based Polymers And Copolymers As Additives For Chemical Mechanical Planarization Slurries
发明人:LARBIG GREGOR; KIRSCH PEER; HENGST MATTHIAS; SHI XIAOBO; STENDER MATTHIAS
权利人:VERSUM MAT US LLC
摘要:Synthesis of triazole- and/or triazolium-based polymers is disclosed. Chemical Mechanical Planarization (CMP) slurries comprise abrasives; activator; oxidizing agent; additive comprising triazole- and/or triazolium-based polymers; and water. The use of the synthesized triazole- and/or triazolium-based polymers in the CMP slurries reduces dishing and erosion in highly selective tungsten slurries.

专利号:WO-2024073211-A1
优先权日:2022-09-29
标题:Guanidinium-based polyionic liquids and their use as additives for chemical mechanical planarization slurries
发明人:LARBIG GREGOR; KIRSCH PEER; SHI XIAOBO
权利人:VERSUM MAT US LLC
摘要:Synthesis of guanidinium-based polymers is disclosed. Chemical Mechanical Planarization (CMP) slurries comprise abrasives; activator; oxidizing agent; additive comprising guanidinium-based polymers; and water. The use of the synthesized guanidinium-based polymers in the CMP slurries reduces dishing and erosion in highly selective tungsten slurries.

专利号:US-9217012-B2
优先权日:2009-04-08
标题 :Inhibitors of protein tyrosine phosphatases
发明人:ZHANG ZHONG-YIN; ZHANG SHENG
权利人:ZHANG ZHONG-YIN; ZHANG SHENG; UNIV INDIANA RES & TECH CORP
摘要:Disclosed herein are compounds that selectively inhibit members of the PTP family of enzymes. Synthesized compounds demonstrated selective inhibition of TC-PTP. Also provided are methods of using the compounds and formulations containing the compounds. Also described is a fluorescence-tagged combinatorial library synthesis and screening method. And methods of using these compounds to effect enzyme activity both in cells and in vitro as well as method of using these compounds to treat diseases in human and animals.

专利号:US-2025215130-A1
优先权日:2022-04-11
标 题:Polycationic Polymer Or Copolymer Having Different Cation Types For Slurries In Chemical Mechanical Planarization
发明人:LARBIG GREGOR; SHI XIAOBO
权利人:MERCK PATENT GMBH; VERSUM MAT US LLC
摘要:Synthesis of polycationic polymer or copolymer is disclosed. The polycationic polymer or copolymer are formed by at least one first cationic monomer and at least one second cationic monomer wherein the first cationic monomer and the second cationic monomer have different cationic groups; such as imidazolium group and non-imidazolium group. Chemical Mechanical Planarization (CMP) slurries comprise abrasives; activator; oxidizing agent; additive comprising polycationic polymer or copolymer; and water are also disclosed. The use of the synthesized polycationic polymer or copolymer in the CMP slurries reduces dishing and erosion in highly selective tungsten slurries.

供应商参考报价(招募中)

品牌试剂参考报价(招募中)

📌 第三方产品分析报告

✅ COA系统入驻 | 共享模式

合成参考文献


摘要:Farmaco, Edizione Scientifica., 30(399), 1975 []
摘要:HANSCH,C ET AL. (1995)
摘要:M. V. Park, J. Chem. Soc. (A) 1966, 816.
参考文献:10.1038/s41467-021-24482-1
摘要:Wu P, Chen D, Ding W, Wu P, Hou H, Bai Y, Zhou Y, Li K, Xiang S, Liu P, Ju J, Guo E, Liu J, Yang B, Fan J, He L, Sun Z, Feng L, Wang J, Wu T, Wang H, Cheng J, Xing H, Meng Y, Li Y, Zhang Y, Luo H, Xie G, Lan X, Tao Y, Li J, Yuan H, Huang K, Sun W, Qian X, Li Z, Huang M, Ding P, Wang H, Qiu J, Wang F, Wang S, Zhu J, Ding X, Chai C, Liang L, Wang X, Luo L, Sun Y, Yang Y, Zhuang Z, Li T, Tian L, Zhang S, Zhu L, Chang A, Chen L, Wu Y, Ma X, Chen F, Ren Y, Xu X, Liu S, Wang J, Yang H, Wang L, Sun C, Ma D, Jin X, Chen G. The trans-omics landscape of COVID-19. Nature Communications. 2021 Jul 27;12(1):4543. doi: 10.1038/s41467-021-24482-1.
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