CAS: 2937-54-4; 2-Aminoethane-1-Sulfonothioic S-Acid
该化合物是一个含硫的氨酸衍生物,在结构上与陶林有关,其特点是存在硫醇(-SH)组,与非硫醇对口相比,具有独特的化学特性.Thiotaurine以其潜在的抗氧化特性而著称,这可能有助于保护细胞免受氧化性压力,在水中可溶解,使其生物可用于各种生物应用.该化合物在...
- 英文名称2-Aminoethane-1-Sulfonothioic S-Acid
- 中文名称2-氨基乙硫代磺酸
- IUPAC名称2-aminoethane-1-sulfonothioic O-acid
- 其它别名Ethanesulfonothioic Acid, 2-Amino-; 2-Aminoethanethiosulfonic Acid; 2-Aminoethanesulfonothioic Acid; 2-Aminoethanethiosulfonic S-Acid; Thiotaurine; 2-Aminoethanesulfonothioic O-Acid; Thiotaurine Thiotaurine
- CAS编号2937-54-4
- MFCD编号:MFCD04038125
- EINECS号:220-918-7
- FDA UNII编号:NQZ2D7AO62
- 分子式:C2H7NO2S2分子量:141.21
- 产品CID: 1275640
- 产品分类化学试剂 → 有机试剂
物理性质
- 熔点213-214 °C
- 沸点324.6 °C at 760mmHg
- 闪点150.1 °C
- 密度1.541g/cm3
- pKa:-0.25±0.10(预测)
- PSA:93.35
- LogP:0.8946
- 折射率1.622
- 蒸汽压4.94E-05mmHg at 25°C
- 敏感性遵照规定使用和储存则不会分解。
- 外观形态固体
- 储存条件密闭于阴凉干燥环境环境中
- 产品应用该化合物是陶林的合成氨酸衍生物,以其抗氧化剂和细胞保护特性著称.它有助于中和活性氧物种(ROS),保护细胞免受氧化性压力,特别是皮肤的氧化性紧张.TIOTOURAINE通常用于化妆和皮肤护理配方,以对抗环境损害和支持健康的皮肤功能.它的机制包括清扫自由基和支持细胞防御系统.
MSDS等安全信息
上下游产品
CAS号300-84-5 2-氨基乙烷亚磺酸合成工艺路线路线简述
📜亚牛磺酸置于sodium Hydroxide,Sulfur体系中,化学反应生成2-氨基乙硫代磺酸
参考文献:Cavallini Et Al.,Biochemical Preparations,1963,Vol. 10,P. 72
标题:Cavallini Et Al.,Biochemical Preparations,1963,Vol. 10,P. 72
专利信息
专利号:US-7087743-B2
优先权日:2000-02-11
标 题 :Oligonucleotides and use of oligonucleotides modulating the expression of enzymes involved in the synthesis of melanic pigments, as depigmentation agents
发明人：KURFURST ROBIN; JOLY REGINE
权利人:LVMH RECH
摘要:The present invention relates to novel oligonucleotide sequences and also to derivatives thereof. n These novel oligonucleotide sequences are capable of hybridizing specifically with the gene or with a product of the gene encoding tyrosinase, or with the gene or a product of the gene encoding tyrosinase-related-protein 1 (TRP-1). n The present invention also relates to the use of these novel oligonucleotide sequences as a depigmenting or bleaching agent in a cosmetic composition or in a dermatological composition.
专利号:CN-101067135-A
优先权日:2000-02-11
标题 :Novel oligonucleotides and use of oligonucleotides modulating the expression of enzymes involved in the synthesis of melanic pigments, as depigmentation agents
专利号:JP-2008043334-A
优先权日:2000-02-11
标 题:New oligonucleotide and use of oligonucleotide modulating expression of enzyme involved in synthesis of melanic pigment, as decolorant
专利号:EP-1255827-B1
优先权日:2000-02-11
标 题 :Oligonucleotides and their use for modulating the expression of tyrosinase involved in the synthesis of melanic pigments
专利号:US-2004014700-A1
优先权日:2000-02-11
标题:Novel oligonucleotides and use of oligonucleotides modulating the expression of enzymes involved in the synthesis of melanic pigments, as depigmentation agents
专利号:EP-1255827-B8
优先权日:2000-02-11
标题 :Oligonucleotides and their use for modulating the expression of tyrosinase involved in the synthesis of melanic pigments
供应商参考报价(招募中)
品牌试剂参考报价(招募中)
📌 第三方产品分析报告
主要参考文献
1: Baseggio Conrado A, Capuozzo E, Mosca L, Francioso A, Fontana M. Thiotaurine: From Chemical and Biological Properties to Role in H2S Signaling. Adv Exp Med Biol. 2019;1155:755-771. doi: 10.1007/978-981-13-8023-5_66. 1866(12):130225. doi: 10.1016/j.bbagen.2022.130225. Epub 2022 Aug 18.
3: Wang D, Xie A, Luo J, Li L, Zhang Z, Deng W, Yang B, Chang Y, Liang Y. Thiotaurine inhibits melanoma progression by enhancing Ca2+ overload- induced cellular apoptosis. J Dermatol Sci. 2025 Apr;118(1):29-37. doi: 10.1016/j.jdermsci.2025.03.001. Epub 2025 Mar 15.
803:145-55. doi: 10.1007/978-3-319-15126-7_13. 240(1):34-40. doi: 10.1086/712396. Epub 2021 Feb 9.
合成参考文献
参考文献:10.1002/jat.1709
摘要:Marziaz ML, Frazier K, Guidry PB, Ruiz RA, Petrikovics I, Haines DC. Comparison of brain mitochondrial cytochrome c oxidase activity with cyanide LD50 yields insight into the efficacy of prophylactics. J of Applied Toxicology. 2011 Jul 13;33(1):50–5. doi: 10.1002/jat.1709.
📝 需求与反馈
尽可能描述清楚需求与问题信息
