CAS: 22282-58-2; 2-Iodo-3-Methylpyridine

该化合物是卤化的衍生物,广泛用作有机合成和制药研究的多功能中间体,其主要优点包括碘和甲基功能组的存在,这增强了其在诸如铃木-宫浦和尼基什等交叉反应中的回动性.2点的碘替代组有利于选择性功能化,而3点的甲基组则有助于消毒和电子调节.这一化合物对于发展环球化合物和生物活性分子特别有价值.在标准条件下和与各种反应条件相容的情况下,其稳定性使其成为复杂的分子结构的可靠建筑.

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22282-62-8 1227573-52-5 445373-09-1

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上下游产品

3-methylpyridin-2-yl trifluoromethanesulfonate 2-bromo-3-picoline 3-methyl-2-(toluene-4-sulfonyl)-pyridine

合成工艺路线路线简述

    📜1-(3-Methylpyridin-2-yl)-2,4,6-Triphenylpyridin-1-Ium;Iodide 以71%的收率获得
    参考文献:Eweiss N. F.; Katritzky A. R.; Nie P.-L.; Ramsden C. A.,Synthesis,1977,No 9,634-635
    标题:Eweiss N. F.; Katritzky A. R.; Nie P.-L.; Ramsden C. A.,Synthesis,1977,No 9,634-635

    海关参考信息

    专利信息


    专利号:US-3989685-A
    优先权日:1972-06-29
    标题 :Process for making a 2'-halopenicillin
    发明人:TANIDA HIROSHI; TSUJI TERUJI
    权利人:SHINOGI CO
    摘要:A 2'-halopenicillin compound is prepared from a penicillin-1-oxide compound by the action of an acid halide in the presence of a base. The product on heating rearranges to a 3-halo-3-methylcepham compound which itself gives a 3-methyl-3-cephem compound on further heating. A 2'-halopenicillin compound gives a 3-methyl-3-cephem compound on heating. The 2'-halopenicillin compounds, 3-halo-3-methylcepham compound and 3-methyl-3-cephem compounds are antibacterials which are also useful as intermediates for the synthesis of other penicillins and cephalosporins.

    专利号:US-8828907-B2
    优先权日:2009-03-25
    标题:Active ingredient combinations having insecticidal and acaricidal properties
    发明人:HUNGENBERG HEIKE; JESCHKE PETER; VELTEN ROBERT; THIELERT WOLFGANG
    权利人:HUNGENBERG HEIKE; JESCHKE PETER; VELTEN ROBERT; THIELERT WOLFGANG; BAYER CROPSCIENCE AG
    摘要:The present invention relates to novel active compound combinations comprising, firstly, at least one known compound of the formula (I) n nin whichn nR 1 and A have the meanings given in the descriptionn nand, secondly, at least one further known active compound from the class of the chitin synthesis inhibitors, the molting hormone agonists or other classes, which combinations are highly suitable for controlling animal pests such as insects and unwanted acarids.

    专利号:CN-111170991-B
    优先权日:2014-07-11
    标题 :Antiproliferative compounds and methods of synthesis thereof

    专利号:CN-111170991-A
    优先权日:2014-07-11
    标 题:Antiproliferative compounds and methods of synthesis thereof

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    ✅ COA系统入驻 | 共享模式

    合成参考文献


    参考文献:10.1055/s-0036-1591541
    摘要:Forgione P, Chen F, Chacón-Huete F, El-Husseini H. Convenient and Inexpensive Route to Sulfonylated Pyridines via SNAr Reaction of Electron-Rich Pyridines by Iron Catalysis. Synthesis. 2018 Feb 20;50(09):1914–20. doi: 10.1055/s-0036-1591541.
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