CAS: 21643-38-9; 4-Hexylbenzoic Acid

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CAS号49763-69-1 4-N-己基苯甲醛 | CAS号1077-16-3 苯己烷 | CAS号79-37-8 草酰氯 | CAS号124-38-9 二氧化碳 | CAS号23703-22-2 1-溴-4-己苯 | CAS号37592-72-6 4'-己基苯乙酮 | CAS号111833-05-7 4-(4-hexylbenzo... | CAS号38289-30-4 反式-4-己基环己烷甲酸 | CAS号67589-85-9 cis 4-n-hexylcy... | CAS号50606-95-6 4-己基苯甲酰氯 | CAS号118578-88-4 (4-hexylphenyl)... | CAS号67589-91-7 4-hexylcyclohex... | CAS号58999-67-0 1-(chloromethyl... | CAS号38580-62-0 (4-hexoxyphenyl... | CAS号38454-21-6 4-正丁氧苯基 4-正苯甲酸己酯

📜己基苯置于jones Reagent体系中,用 丙酮,三氟乙酸 用作溶剂,化学反应 0.5H,反应生成4-己基苯甲酸
参考文献:新的有效的白三烯c4和d4拮抗剂.1.合成与构效关系.
标题:新的有效的白三烯c4和d4拮抗剂.1.合成与构效关系.
摘要:(p-戊基肉桂酰基)邻氨基苯甲酸(3A)对ltd4-诱导的豚鼠回肠平滑肌收缩和ltc4诱导的豚鼠支气管收缩具有中等程度的拮抗活性.对3A的疏水部分(肉桂酰基部分)和亲水部分(邻氨基苯甲酸酯部分)进行了修饰.揭示了一系列的8-(苯甲酰基氨基)-2-四唑-5-基-1,4-苯并二恶烷和8-(苯甲酰基氨基)-2-四唑-5-基-4-氧代-4H-1-苯并吡喃.白三烯c4和d4的有效拮抗剂.在这两个系列中,Ono-Rs-347(18K)和ono-Rs-411(19H)分别是最有效和口服活性的拮抗剂.讨论了构效关系.
Doi:10.1021/jm00396A013

专利信息

专利号:US-7999090-B2
优先权日:2000-07-07
标 题:Fungal cell wall synthesis gene
发明人：TSUKAHARA KAPPEI; HATA KATSURA; SAGANE KOJI; NAKAMOTO KAZUTAKA; TSUCHIYA MAMIKO; WATANABE NAOAKI; OHBA FUMINORI; TSUKADA ITARU; UEDA NORIHIRO; TANAKA KEIGO; KAI JUNKO
权利人:EISAI R&D MAN CO LTD
摘要:The present invention provides isolated DNA encoding a GWT1 protein having activity to confer resistance of a fungus against a compound of formula Ia, and wherein a defect of a function of the GWT1 protein leads to a decrease in the amount of a glycosylphosphatidylinositol (GPI)-anchored protein in the cell wall of a fungus.

专利号:US-9217012-B2
优先权日:2009-04-08
标题 :Inhibitors of protein tyrosine phosphatases
发明人：ZHANG ZHONG-YIN; ZHANG SHENG
权利人:ZHANG ZHONG-YIN; ZHANG SHENG; UNIV INDIANA RES & TECH CORP
摘要:Disclosed herein are compounds that selectively inhibit members of the PTP family of enzymes. Synthesized compounds demonstrated selective inhibition of TC-PTP. Also provided are methods of using the compounds and formulations containing the compounds. Also described is a fluorescence-tagged combinatorial library synthesis and screening method. And methods of using these compounds to effect enzyme activity both in cells and in vitro as well as method of using these compounds to treat diseases in human and animals.

专利号:MX-2008013487-A
优先权日:2000-07-07
标 题 :SYNTHESIS GEN OF THE FUNGAL CELL WALL.