CAS: 1878-81-5; 2-(4-Acetylphenoxy)Acetic Acid

该化合物是一种合成有机化合物,其成分包括乙酰和苯氧乙酸功能组,其结构在制药和农用化学合成中起到中间作用,特别是在开发需要苯球或碳oxylic酸脂的活性成分方面.该化合物的乙酰组增加了进一步衍生的再活性,而苯氧乙酸基柱则与同源或进化反应相容.它通常用于研究环境,用于研究结构-活动关系或作为热循环化学的前体.该产品的特点通常是高纯度(>95%)和在标准储存条件下稳定,确保合成应用的一贯性能.

结构式图片

欧盟法规

ECHA物质C&L通报REACH预注册

上下游产品

CAS号6296-28-2 methyl 2-(4-ace... | CAS号79-14-1 羟基乙酸 | CAS号13329-40-3 4'-碘代苯乙酮 | CAS号51828-69-4 ethyl 2-(4-acet... | CAS号79-11-8 氯乙酸 | CAS号99-93-4 对羟基苯乙酮 | CAS号79-08-3 溴乙酸 | CAS号105-36-2 溴乙酸乙酯 | CAS号50-00-0 甲醛 | CAS号201230-82-2 carbon monoxide | CAS号99-93-4 对羟基苯乙酮 | CAS号100-06-1 对甲氧基苯乙酮 | CAS号6951-76-4 Acetic acid,2-[... | CAS号6296-28-2 methyl 2-(4-ace... | CAS号52299-08-8 2-[4-(carboxyme...

合成工艺路线路线简述

    📜Methyl-[4-(1-Oxoethyl)Phenoxy] Acetate置于水,Sodium Hydroxide体系中,用 四氢呋喃 用作溶剂,化学反应生成4-乙酰苯氧基乙酸
    参考文献:Antibacterial Small Molecules And Methods For Their Synthesis
    标题:Antibacterial Small Molecules And Methods For Their Synthesis
    摘要:本发明一般涉及提供抗菌治疗剂和制剂的化合物,以及使用和制备抗菌化合物的相关方法.本发明的抗菌化合物包括查尔酮,烷基嘧啶,氨基嘧啶和氰基吡啶化合物及其衍生物,其最小抑菌浓度(mic)与广泛使用的常规抗菌化合物相似或更低.

    海关参考信息

    专利信息


    专利号:US-6531470-B1
    优先权日:1998-01-23
    标题:Oxazolidinone combinatorial libraries, compositions and methods of preparation
    发明人:GORDEEV MIKHAIL F; LUEHR GARY W; PATEL DINESH V; NI ZHI-JIE; GORDON ERIC
    权利人:UPJOHN CO
    摘要:Oxazolidinones and methods for their synthesis are provided. Also provided are combinatorial libraries comprising oxazolidinones, and methods to prepare the libraries. Further provided are methods of making biologically active oxazolidinones as well as pharmaceutically acceptable compositions comprising the oxazolidinones. The methods of library preparation include the attachment of oxazolidinones to a solid support. The methods of compound preparation in one embodiment involve the reaction of an iminophosphorane with a carbonyl containing polymeric support.

    专利号:US-6005103-A
    优先权日:1993-11-19
    标题 :Pyrone derivatives as protease inhibitors and antiviral agents
    发明人:DOMAGALA JOHN MICHAEL; LUNNEY ELIZABETH; PARA KIMBERLY SUZANNE; PRASAD JOSYULA VENKATA NAGENDR; TAIT BRADLEY DEAN
    权利人:WARNER LAMBERT CO
    摘要:The present invention relates to novel tri- and tetrasubstituted pyrones and related structures which potently inhibit the HIV aspartyl protease blocking HIV infectivity. The pyrone derivatives are useful in the development of therapies for the treatment of bacterial and viral infections and diseases, including AIDS. The present invention is also directed to methods of synthesis of multifunctionalized pyrones and of related structures.

    专利号:US-6562844-B2
    优先权日:1998-01-23
    标 题:Oxazolidinone combinatorial libraries, compositions and methods of preparation
    发明人:GORDEEV MIKHAIL F; LUEHR GARY W; PATEL DINESH V; NI ZHI-JIE; GORDON ERIC
    权利人:UPJOHN CO
    摘要:Oxazolidinones and methods for their synthesis are provided. Also provided are combinatorial libraries comprising oxazolidinones, and methods to prepare the libraries. Further provided are methods of making biologically active oxazolidinones as well as pharmaceutically acceptable compositions comprising the oxazolidinones. The methods of library preparation include the attachment of oxazolidinones to a solid support. The methods of compound preparation in one embodiment involve the reaction of an iminophosphorane with a carbonyl containing polymeric support.

    专利号:US-9217012-B2
    优先权日:2009-04-08
    标题 :Inhibitors of protein tyrosine phosphatases
    发明人:ZHANG ZHONG-YIN; ZHANG SHENG
    权利人:ZHANG ZHONG-YIN; ZHANG SHENG; UNIV INDIANA RES & TECH CORP
    摘要:Disclosed herein are compounds that selectively inhibit members of the PTP family of enzymes. Synthesized compounds demonstrated selective inhibition of TC-PTP. Also provided are methods of using the compounds and formulations containing the compounds. Also described is a fluorescence-tagged combinatorial library synthesis and screening method. And methods of using these compounds to effect enzyme activity both in cells and in vitro as well as method of using these compounds to treat diseases in human and animals.

    专利号:EP-0729465-B1
    优先权日:1993-11-19
    标 题:Pyrone derivatives as protease inhibitors and antiviral agents
    发明人:DOMAGALA JOHN MICHAEL; LUNNEY ELIZABETH; PARA KIMBERLY SUZANNE; PRASAD JOSYULA VENKATA NAGENDR; TAIT BRADLEY DEAN
    权利人:PARKE DAVIS & CO
    摘要:The present invention relates to novel tri- and tetrasubstituted pyrones and related structures which potently inhibit the HIV aspartyl protease blocking HIV infectivity. The pyrone derivatives are useful in the development of therapies for the treatment of bacterial and viral infections and diseases, including AIDS. The present invention is also directed to methods of synthesis of multifunctionalized pyrones and of related structures.

    专利号:US-7002020-B1
    优先权日:1998-01-23
    标题:Oxazolidinone combinatorial libraries, compositions and methods of preparation
    发明人:GORDEEV MIKHAIL F; LUEHR GARY W; PATEL DINESH V
    权利人:UPJOHN CO
    摘要:Oxazolidinones and methods for their synthesis are provided. Also provided are combinatorial libraries comprising oxazolidinones, and methods to prepare the libraries. Further provided are methods of making biologically active oxazolidinones as well as pharmaceutically acceptable compositions comprising the oxazolidinones. The methods of library preparation include the attachment of oxazolidinones to a solid support. The methods of compound preparation in one embodiment involve the reaction of an iminophosphorane with a carbonyl containing polymeric support.

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    品牌试剂参考报价(招募中)

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    主要参考文献

    [参考文献]: C Schleissner, Et Al. Aerobic Catabolism Of Phenylacetic Acid In Pseudomonas Putida U: Biochemical Characterization Of A Specific Phenylacetic Acid Transport System And Formal Demonstration That Phenylacetyl-Coenzyme A Is A Catabolic Intermediate. J Bacteriol. 1994 Dec;176(24):7667-76.

    合成参考文献


    摘要:S109 | PARCEDC | List of 7074 potential endocrine disrupting compounds (EDCs) by PARC T4.2 | DOI:10.5281/zenodo.10944198
    摘要:A. J. Hoefnagel, J. C. Monshouwer, E. C. G. Snorn and B. M. Wepster, J. Am. Chem. Soc. 95, 5350 (1973).
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