CAS: 16312-21-3; 3-Methylthiazolidine-2,4-Dione

相似化合物

37868-80-7 37868-77-2 39137-26-3

上下游产品

CAS号2295-31-0 2,4-噻唑烷二酮 | CAS号74-88-4 碘甲烷 | CAS号37929-27-4 USAF K-1338 | CAS号79-11-8 氯乙酸 | CAS号4807-55-0 3-甲基罗丹宁 | CAS号39131-10-7 potassium,1,3-t... | CAS号598-52-7 N-甲硫脲 | CAS号68-11-1 硫代乙醇酸(TGA) | CAS号74-89-5 氨基甲烷 | CAS号2365-48-2 巯基乙酸甲酯

📜S-Methylthiourea置于氯乙酸体系中,用 水 用作溶剂,以79%的收率获得3-甲基-1,3-噻唑烷-2,4-二酮
参考文献:Azolidines As Beta-3 Adrenergic Receptor Agonists
标题:Azolidines As Beta-3 Adrenergic Receptor Agonists
摘要:本发明提供了具有以下结构式的i号化合物的药物或药用盐,其中a,X,Y,Z,W,R1,R2,R3,R4,R5和r6的定义如前所述.这些化合物可用于治疗或抑制与胰岛素抵抗或高血糖(通常与肥胖或葡萄糖不耐受有关)相关的代谢紊乱,动脉粥样硬化,胃肠疾病,神经源性炎症,青光眼,眼压增高和频繁排尿,特别是在治疗或抑制2型糖尿病方面特别有用.

专利信息

专利号:WO-2009148195-A1
优先权日:2008-06-02
标题:5-(4-hydroxybenzyl)thiazolidine-2,4-dione as intermediate for synthesis of thiazolidinedione based compounds and process for preparing the same
发明人：PARK JIN OH; KIM YONG GIL; SON HAN IL; LEE YUN JEONG; KIM EUN MI
权利人:DAEBONG LS LTD; PARK JIN OH; KIM YONG GIL; SON HAN IL; LEE YUN JEONG; KIM EUN MI
摘要:The present invention relates to 5-(4-hydroxybenzyl)thiazolidine-2,4-dione represented by the following Chemical Formula [1], which is useful as an intermediate for synthesis of thiazolidinedione based compounds, a method for preparing the compound, and a method for preparing pioglitazone or pioglitazone hydrochloride, which is a thiazolidinedione based drug and useful in treating and preventing diabetes, using the 5-(4-hydroxybenzyl)thiazolidine-2,4-dione represented by Chemical Formula [1] as an intermediate:

专利号:US-6747142-B1
优先权日:2000-09-05
标 题:Multiple methoxyoxalamido and succinimido precursors for nucleophilic addition
发明人：POLOUCHINE NIKOLAI N
权利人:FIDELITY SYSTEMS INC
摘要:Compounds and the synthesis of compounds containing multiple precursor groups and allowing the efficient synthesis of highly functionalized oligonucleotides and oligomers are provided. Also, a branching unit that helps to further increase the density of functional groups on synthetic oligonucleotides and oligomers is provided.

专利号:US-6362166-B1
优先权日:1996-05-14
标 题 :Antipicornaviral compounds and methods for their use and preparation
发明人：WEBBER STEPHEN E; DRAGOVICH PETER S; PRINS THOMAS J; REICH SIEGFRIED H; LITTLE JR THOMAS L; LITTLEFIELD ETHEL S; MARAKOVITS JOSEPH T; BABINE ROBERT E; BLECKMAN TED M
权利人:AGOURON PHARMA
摘要:Picornaviral 3C protease inhibitors, obtainable by chemical synthesis, inhibit or block the biological activity of picornaviral 3C proteases. These compounds, as well as pharmaceutical compositions that contain these compounds, are suitable for treating patients or hosts infected with one or more picornaviruses. Several novel methods and intermediates can be used to prepare the novel picornaviral 3C protease inhibitors of the present invention.

专利号:US-3642786-A
优先权日:1967-05-29
标题 :Merocyanine dyes
发明人：HESELTINE DONALD W; LINCOLN LEWIS L
权利人:EASTMAN KODAK CO
摘要:MEROCYANINE DYES DERIVED FROM B,B-NAPHTHOTHIAZOLE HAVE BEEN FOUND TO BE EXCELLENT SPECTRAL SENSITIZERS FOR SILVER HALIDE EMULSIONS. THESE DYES HAVE SUBSTANTIALLY THE SAME SENSITIZATION PROPERTIES AS KNOWN CORRESPONDING A-NAPTHTHOTHIAZOLE DYES. HOWEVER, THE B,B-NAPHTHOTHIAZOLE NUCLEUS DOES NOT REQUIRE THE USE OF A COARCINOGENIC INTERMEDIATE (B-NAPHTHYLAMINE) IN ITS SYNTHESIS.