CAS: 1125-99-1; 1-(Cyclohex-1-En-1-yl)Pyrrolidine

相似化合物

19805-73-3 102745-76-6 706786-75-6

上下游产品

pyrrolidine cyclohexanone 1-Pyrrolidin-1-yl-cyclohexanecarbonitrile 1-brom°Cyclohex-1-ene 2-(Pyrrolidin-1-yl)bicyclo[3.3.1]nonan-9-on ethyl 4,5,6,7-tetrahydro-1H-indazole-3-carboxylate 2-(2-[2]naphthyl-ethyl)-cyclohexanone ethyl 2-ox°Cyclohexane carboxylate

📜1-(1-氰基环己基)吡咯烷置于sodium Methylate体系中,用 甲醇 用作溶剂,化学反应生成1-吡咯烷-1-环己烯
参考文献:A Facile Method For Preparing Aminobicyclo[n.1.0]Alkane Derivatives
标题:A Facile Method For Preparing Aminobicyclo[n.1.0]Alkane Derivatives
摘要:
Doi:10.1055/s-1999-3493

专利信息

专利号:US-7157484-B2
优先权日:2003-02-28
标 题 :Method for synthesissing (2s, 3as, 7as)-perhydroindole-2-carboxylic acid and the esters thereof and the use thereof for perindopril synthesis
发明人：DUBUFFET THIERRY; LANGLOIS PASCAL
权利人:SERVIER LAB
摘要:Process for the synthesis of compounds of formula (I): n nwherein R represents hydrogen or a protecting group.n n Application in the synthesis of perindopril and pharmaceutically acceptable salts thereof.

专利号:US-7157485-B2
优先权日:2003-02-28
标题 :Method for synthesizing derivatives of (2S,3AS,7AS)-1-[(S)-alanyl]-octahydro,-1H-indole-2-carboxylic acid and the use thereof for perindopril synthesis
发明人：DUBUFFET THIERRY; LANGLOIS PASCAL
权利人:SERVIER LAB
摘要:Process for the synthesis of compounds of formula (I): n nwherein R 1 represents hydrogen, alkyl or benzyl and R 2 represents a protecting group for the amine function.n n Application in the synthesis of perindopril and pharmaceutically acceptable salts thereof.

专利号:WO-2005049567-A1
优先权日:2003-11-24
标题:A novel synthesis of 2-azabicyclic-3-carboxylic acids, useful as important drug intermediates
发明人：BABU POTLURI RAMESH; HARIHARAKRISHNAN VENKATA SUBRA; SRIHARI TADIMALLA VENKATA; PRASAD KODALI HARI; RAMESH BETINI; MALLAPARAJU GOTTIMUKKALA VENKA
权利人:BABU POTLURI RAMESH; HARIHARAKRISHNAN VENKATA SUBRA; SRIHARI TADIMALLA VENKATA; PRASAD KODALI HARI; RAMESH BETINI; MALLAPARAJU GOTTIMUKKALA VENKA
摘要:A novel process for the preparation of 2-azabicyclo-3-carboxylic acid hydrochloride of formula (I), by reacting the compound of formula (II) with an acylating agent in a non-polar solvent at 0-150 °C to give a compound of formula (III), which is reacted with an enamine of formula (IV) in a non-polar solvent in the presence of an organic base at 0 °C to 150 °C to yield a compound of formula (V), which is hydrolytically cyclised to give a compound of formula (VI) and further catalytically hydrogenated to give the compound of formula (I).

专利号:US-9611217-B2
优先权日:2015-05-06
标题:Synthetic processes of carprofen
发明人：YI LIN; SU XIPING; WERTH PETER
权利人:YI LIN; SU XIPING; WERTH PETER; CHEMWERTH INC
摘要:Methods and intermediates for the synthesis of carprofen and its derivatives starting from cyclohexanone are disclosed.

专利号:EP-1403277-B1
优先权日:2003-02-28
标题:Method for synthesis of (2S,3aS,7aS)-1-((S)-alanyl)-octahydro-1H-indole-2-carboxylic acid derivatives and use in the synthesis of perindopril

专利号:EP-1403277-A1
优先权日:2003-02-28
标 题:Method for synthesis of (2S,3aS,7aS)-1-((S)-alanyl)-octahydro-1H-indole-2-carboxylic acid derivatives and use in the synthesis of perindopril