CAS: 1073-72-9; 4-(Methylthio)Phenol

相似化合物

1879-16-9 1073-29-6 3463-03-4

上下游产品

CAS号98546-51-1 4-甲硫基苯硼酸 | CAS号637-89-8 4-羟基苯硫酚 | CAS号74-88-4 碘甲烷 | CAS号540-38-5 4-碘苯酚 | CAS号67-68-5 二甲基亚砜 | CAS号1879-16-9 4-甲氧基茴香硫醚 | CAS号108-95-2 苯酚 | CAS号5813-48-9 Methanesulfenic... | CAS号35371-03-0 4-碘茴香硫醚 | CAS号73441-60-8 4-thiomethylphe... | CAS号32279-04-2 4-羟苯基二甲基锍甲磺酸盐 | CAS号18333-20-5 3-[4-(甲基硫代)苯氧基]丙酸 | CAS号22945-49-9 tris(4-methylsu... | CAS号67868-84-2 2-羟基-5-(甲基硫代)苯甲醛 | CAS号90-02-8 水杨醛 | CAS号59729-37-2 非昔硝唑 | CAS号1005-35-2 Sulfonium,(4-hy... | CAS号1073-29-6 2-羟基茴香硫醚 | CAS号36089-89-1 1-(4-methylsulf... | CAS号32547-86-7 1-methylsulfany...

1,4-二氯苯置于盐酸,Sodium Thiomethoxide体系中,用 N,N-二甲基甲酰胺 用作溶剂,化学反应 42.5H,反应生成4-(甲硫基)苯酚
参考文献:Simple Syntheses Of Aryl Alkyl Thioethers And Of Aromatic Thiols From Unactivated Aryl Halides And Efficient Methods For Selective Dealkylation Of Aryl Alkyl Ethers And Thioethers
标题:Simple Syntheses Of Aryl Alkyl Thioethers And Of Aromatic Thiols From Unactivated Aryl Halides And Efficient Methods For Selective Dealkylation Of Aryl Alkyl Ethers And Thioethers
摘要:
Doi:10.1055/s-1983-30501

专利信息

专利号:US-7301006-B2
优先权日:2002-07-16
标 题 :Methods and materials for the synthesis of modified peptides
发明人：YOUNG TRAVIS G; KIESSLING LAURA L
权利人:WISCONSIN ALUMNI RES FOUND
摘要:Methods and protected amino acids useful as building blocks (protected monomers) for the synthesis of peptides and proteins that are selectively modified at one or more side-chain hydroxyl groups. Azide-bearing protecting groups allow the selective deprotection of side-chain hydroxyl groups of amino acids after synthesis of a peptide. Reaction conditions for removal of the azide-bearing protecting group can be selected which are substantially orthogonal to those that will remove α-amino protecting groups typically employed in peptide synthesis, such that hydroxyl groups protected with the azide-bearing protecting group remain protected during synthesis of the peptide chain. Various protecting groups which are readily available can be used for protecting potentially reactive side chain groups of amino acids in the peptide or protein to be modified. Preferred side-chain protecting groups are chemically distinguishable from the azide-bearing protecting group and substantially orthogonal reaction conditions can be selected such that side-chain protection of other amino acids is maintained when the azide-bearing protecting group is removed. The use of the azide-bearing protecting group of this invention for one or more hydroxy amino acids during peptide synthesis allows the selective unmasking of those azide-protected side-chain hydroxyl groups and selective modification of the hydroxyl groups that are selectively unmasked. The methods and materials herein are particularly used in synthesis of sulfated, phosphorylated and glycosylated peptides and proteins. Kits and methods of synthesizing a modified peptide or protein using the kits are also provided.

专利号:US-2012029226-A1
优先权日:2009-02-06
标题:Method for the synthesis of chiral alpha-aryl propionic acid derivatives
发明人：KAPTEIN BERNARDUS; VLIEG ELIAS; NOORDUIN WILLEM LIEUWE
权利人:KAPTEIN BERNARDUS; VLIEG ELIAS; NOORDUIN WILLEM LIEUWE
摘要:The present invention provides a method for the synthesis of optically pure α-aryl propionic acid derivatives comprising subjecting the corresponding racemic α-aryl propionic acid derivatives to high sheer or impact forces, such as grinding.

专利号:US-9475837-B2
优先权日:2011-12-23
标题 :Process for the synthesis of therapeutic peptides
发明人：HURLEY FIONN; WEGNER KATARZYNA; FOLEY PATRICK
权利人:IPSEN MFG IRELAND LTD
摘要:The present invention relates to a process for the large-scale synthesis of therapeutic peptides using a Sieber Amide resin, which comprises solid-phase Fmoc-chemistry.

专利号:US-8202985-B2
优先权日:2005-10-31
标 题:Monomer compositions for the synthesis of polynucleotides, methods of synthesis, and methods of deprotection
发明人：DELLINGER DOUGLAS J; TIMAR ZOLTAN; SIERZCHALA AGNIESZKA; DELLINGER GERALDINO; CARUTHERS MARVIN H
权利人:DELLINGER DOUGLAS J; TIMAR ZOLTAN; SIERZCHALA AGNIESZKA; DELLINGER GERALDINO; CARUTHERS MARVIN H; AGILENT TECHNOLOGIES INC; UNIV COLORADO
摘要:Nucleotide monomers, polynucleotides, methods of making each, and methods of deprotecting each, are disclosed. An embodiment of the nucleotide monomer, among others, includes a nucleotide monomer having a heterobase protecting group selected from structures I through III as described herein. An embodiment of the polynucleotide, among others, includes a plurality of nucleotide moieties having a heterobase protecting group selected from one of structures I through III as described herein.

专利号:US-7759471-B2
优先权日:2005-10-31
标题 :Monomer compositions for the synthesis of RNA, methods of synthesis, and methods of deprotection
发明人：DELLINGER DOUGLAS J; TIMAR ZOLTAN; SIERZCHALA AGNIESZKA; DELLINGER GERALDINE; CARUTHERS MARVIN H
权利人:AGILENT TECHNOLOGIES INC; UNIV COLORADO
摘要:Nucleotide monomers, polynucleotides, methods of making each, methods of deprotecting each, and the like are disclosed herein.

专利号:US-2022081407-A1
优先权日:2020-09-11
标题 :Methods of preparing substituted indanes
发明人：STENGEL PETER J; XU RUI; SPENCER STACEY RENEE
权利人:PELOTON THERAPEUTICS INC
摘要:This application discloses methods for the synthesis of substituted indane analogs that modulate HIF-2α activity, as well as key intermediates produced thereby. The synthesis of 3-(((1S,2S,3R)-2,3-difluoro-1-hydroxy-7-(methylsulfonyl)-2,3-dihydro-1H-inden-4-yl)oxy)-5-fluorobenzonitrile was exemplified.