CAS: 103-72-0; Phenyl Isothiocyanate

上下游产品

CAS号75-15-0 二硫化碳 | CAS号463-71-8 硫光气 | CAS号43009-16-1 PhNHCSS-*Et3NH+ | CAS号698-16-8 邻氯苯甲醛肟 | CAS号102-08-9 二苯基硫脲 | CAS号1074-52-8 Carbamodithioic... | CAS号93-98-1 N-苯甲酰替苯胺 | CAS号404-24-0 三氟乙酰苯胺 | CAS号103-70-8 甲酰苯胺 | CAS号109322-16-9 1-[[2-(9-bromoi... | CAS号109322-11-4 1-[[2-(2-chloro... | CAS号109322-26-1 3-[(9-bromoindo... | CAS号109768-66-3 (4-FORMYL-2-MET... | CAS号111782-17-3 1-phenyl-3-tetr... | CAS号105202-01-5 N-phenyl-5-(tri... | CAS号111931-61-4 N-(1,3-benzothi... | CAS号109322-21-6 3-[(2-chloroind... | CAS号107427-77-0 3-anilino-2-cya... | CAS号112107-41-2 3-phenylpyrido[...

三苯基胍 反应生成硫代异氰酸苯酯
参考文献:Self-Resolution Of Alcohol Problems In Young Adulthood: A Process Of Securing Solid Ground
标题:Self-Resolution Of Alcohol Problems In Young Adulthood: A Process Of Securing Solid Ground
摘要:定量研究结果表明,年轻成年人在解决酒精问题时并没有参加支持团体或正式治疗计划.然而,研究人员未能充分解释这个年龄群体中的自我解决过程.因此,作者们使用了扎根理论来更好地阐明年轻成年人为什么以及如何自我解决酒精问题.研究结果表明,在年轻成年人中自我解决酒精问题涉及一个寻找和确保坚实基础的时间过程.这个过程是由个体经历摇摇欲坠的情况引发的,最终开始失去平衡.这些累积事件导致年轻成年人追求个人愿景,并在坚实基础上找到安全立足点,尽管在前进的过程中可能会遇到一些崎岖的地形.
Doi:10.1177/104973202129120115

专利信息

专利号:US-6136984-A
优先权日:1996-04-22
标 题 :Solid phase and combinatorial synthesis of substituted thiophenes and of arrays of substituted thiophenes
发明人：DOERWALD FLORENCIO ZARAGOZA
权利人:NOVO NORDISK AS
摘要:A solid phase method for the synthesis of a plurality of differently substituted thiophenes with a wide variety of side-chain substituents as compounds of potential therapeutic interest is disclosed. The thiophenes are prepared by acylation of a substrate-bound primary or secondary amine with cyanoacetic acid and reaction of the resulting cyanoacetamide with an isothiocyanate in the presence of a base. Alkylation with an appropriate alkyl halide, followed by Thorpe-Ziegier-cyclization yields differently substituted, support-bound 3-aminothiophenes. These may be screened on the substrate or cleaved from the substrate and then screened in solution. Alternatively, the resin-bound 3-amino thiophenes or the synthetic intermediates can be subjected to further synthetic transformations (N-acylation, reduction) on the support, which permits the preparation of further therapeutically interesting compounds. The efficient synthesis of a wide variety of thiophenes using automated synthesis technology of the present method makes these compounds attractive candidates for the generation and rapid screening of diverse thiophene-based libraries. The method disclosed here provides an easy and fast access to highly diverse heterocyclic compounds of therapeutic interest, amenable to automatization.

专利号:US-5847150-A
优先权日:1996-04-24
标题 :Solid phase and combinatorial synthesis of substituted 2-methylene-2, 3-dihydrothiazoles and of arrays of substituted 2-methylene-2, 3-dihydrothiazoles
发明人：DORWALD FLORENCIO ZARAGOZA
权利人:NOVO NORDISK AS
摘要:A solid phase method for the synthesis of a plurality of differently substituted 2-methylenethiazoles with a wide variety of side-chain substituents as compounds of potential therapeutic interest. The 2-methylenethiazoles are prepared by acylation of a substrate-bound primary or secondary amine with cyanoacetic acid and reaction of the resulting cyanoacetamide with an isothiocyanate in the presence of a base. Alkylation with an appropriate alkyl halide under acidic conditions yields differently substituted, support-bound 2-methylene-2,3-dihydrothiazoles. These may be screened on the substrate or cleaved from the substrate and then screened in solution. The efficient synthesis of a wide variety of 2-methylenethiazoles using automated synthesis technology of the present method makes these compounds attractive candidates for the generation and rapid screening of diverse thiazole-based libraries. The method disclosed here provides an easy and fast access to highly diverse heterocyclic compounds of therapeutic interest, amenable to automatization.

专利号:US-6818777-B2
优先权日:2000-12-07
标 题:Intermediates for synthesis of vinblastine compound and method for synthesizing the intermediate
发明人：FUKUYAMA TOHRU; TOKUYAMA HIDETOSHI
权利人:JAPAN SCIENCE & TECH AGENCY
摘要:Intermediates A, which are important in the whole synthesis of vindoline; and a method of synthesizing intermediates respectively represented by the general formulae B and C. By the method, the target intermediates are effectively synthesized with satisfactory reproducibility. This synthesis method is especially suitable for mass production. General formula A General formula B General formula C.

专利号:US-5350851-A
优先权日:1992-03-16
标题 :Intermediates and a process for synthesis of tetrahydropteridine C6-stereoisomers, including (6S)-tetrahydrofolate and N5-formyl-(6S)-tetrahydrofolate
发明人：BAILEY STEVEN W; AYLING JUNE E
权利人:UNIV SOUTH ALABAMA
摘要:Intermediates and a process for the synthesis of 6-monosubstituted tetrahydropteridine C6-stereoisomers, including (6S)-tetrahydrofolic acid. The intermediates are shown in their two enantiomeric forms as follows: ##STR1## wherein R 1 and R 2 are the same or different and represent hydrogen, methyl, hydroxy, amino, alkyl or dialkylamino, alkoxy, benzyloxy, or benzylthio; R 3 represents an alkene, alkyne, cycloalkyl, benzyl, alkyl (substituted with hydroxy, acetoxy, benzyloxy, alkoxy, alkylthio, amino, carboxy, oxo, or phosphate), a protected aldehyde, or ##STR2## wherein n=1 or 2, R 4 is hydrogen, formyl, methyl, or propargyl, and ZZ represents an amino acid or amino acid polymer.

专利号:WO-2023198025-A1
优先权日:2022-04-11
标题:Synthesis method and synthesis device for organic nitrogen-containing compound
发明人：LI GUANGQIN; Liao Peisen; XIAN JIAHUI; LI SUISHENG; ZHANG YAWEI
权利人:UNIV SUN YAT SEN
摘要:The present invention relates to the field of organic synthesis, specifically to a synthesis method and synthesis device for an organic nitrogen-containing compound. Provided in the present invention is a synthesis method for an organic nitrogen-containing compound. In the method provided in the present invention, a porous carbon material is used as a catalyst, organic nitrogen-containing compounds such as an oxime, an amine, a nitrile and an amino acid are synthesized by means of an electro-catalysis method, byproducts are unlikely to generate, and the method is safe and environmentally friendly. Experiments show that organic nitrogen-containing compounds such as an amino acid, an oxime, an amine and a nitrile are successfully synthesized by using the method of the present invention, and the method has good Faraday efficiency and yield. In the present application, the synthesis of the above organic nitrogen-containing compounds can be realized by using nitrogen oxide waste gas or waste water as a raw material; and by converting the nitrogen oxide waste gas or waste water, the utilization of waste is realized, and the benefits are maximized. Further provided in the present invention is a synthesis device for an organic nitrogen-containing compound, which device is used for solving the defects of high energy consumption, long consumption time, and complex product separation and purification of existing synthesis methods.

专利号:US-5679773-A
优先权日:1995-01-17
标题 :Reagants and methods for immobilized polymer synthesis and display
发明人：HOLMES CHRISTOPHER P
权利人:AFFYMAX TECH NV
摘要:Compounds and methods for solid phase synthesis of organic molecules including peptides, oligonucleotides, benzodiazepines, beta -turn mimetics, and prostaglandins. The present invention provides new reagents in the form of linking groups and resins and substrates having attached linking groups which are useful in solid phase synthesis of high density arrays of organic molecules. The invention also provides methods which increase yields of various organic synthesis strategies.