CAS: 66893-81-0; N-Tert-Butyl-1-(1-Oxidopyridin-4-yl)Methanimine Oxide

该化合物是一种化学化合物,其独特结构包括一个环和一个硝基子功能组,这种化合物通常具有稳定,无色,在室温下不苍白的黄色固体等特性,其作为旋转陷阱的作用是众所周知的,它能够捕捉各种化学反应中的自由基,从而在与氧化压力和激进化学有关的研究中具有价值.

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上下游产品

isonicotinaldehyde 1-oxide N-tert-Butylhydroxylamine N-tertbutylhydroxylamine hydr°Chlorideisonicotinaldehyde 1-oxide N-tert-Butylhydroxylamine 24H33N2O5C24H33N2O5

合成工艺路线路线简述

    📜4-吡啶醛 N-氧化物,N-叔丁基羟胺 以35%的收率获得产物n-叔丁基-α-(4-吡啶基-1-氧)硝酮
    参考文献:Spin Trapping Of Hydroxyl Radical In The Troposphere For Determination By Electron Spin Resonance And Gas Chromatography/mass Spectrometry
    标题:Spin Trapping Of Hydroxyl Radical In The Troposphere For Determination By Electron Spin Resonance And Gas Chromatography/mass Spectrometry
    摘要:
    DOI:10.1021/ac00251A015

    海关参考信息

    专利信息


    专利号:US-5405967-A
    优先权日:1993-10-22
    标题 :Spin-trap molecules 2-trifluoromethyl- of 5,5-dimethyl-1-dyrroline-N-oxide
    发明人:JANZEN EDWARD G; ZHANG YONG-KANG
    权利人:OKLAHOMA MED RES FOUND
    摘要:Novel spin traps comprising 2-trifluoromethyl-1-DMPO or derivatives thereof have now been found. An effective synthesis method for these spin traps is also disclosed.

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    ✅ COA系统入驻 | 共享模式

    合成参考文献


    参考文献:10.1016/0891-5849(96)00039-1
    摘要:Schaefer CF, Janzen EG, West MS, Poyer JL, Kosanke SD. Blood chemistry changes in the rat induced by high doses of nitronyl free radical spin traps. Free Radic Biol Med. 1996;21(4):427–36. doi: 10.1016/0891-5849(96)00039-1.
    参考文献:10.1016/0006-291x(85)91042-3
    摘要:Mossoba MM, Gutierrez PL. Diaziquone as a potential agent for photoirradiation therapy: Formation of the semiquinone and hydroxyl radicals by visible light. Biochemical and Biophysical Research Communications. 1985 Oct;132(1):445–52. doi: 10.1016/0006-291x(85)91042-3.
    摘要:Riesz P, Christman CL. Sonochemical free radical formation in aqueous solutions. Fed Proc. 1986 Sep;45(10):2485–92.
    参考文献:10.1016/s1383-5718(02)00073-6
    摘要:Li Y, Seacat A, Kuppusamy P, Zweier JL, Yager JD, Trush MA. Copper redox-dependent activation of 2-tert-butyl(1,4)hydroquinone: formation of reactive oxygen species and induction of oxidative DNA damage in isolated DNA and cultured rat hepatocytes. Mutation Research/Genetic Toxicology and Environmental Mutagenesis. 2002 Jul;518(2):123–33. doi: 10.1016/s1383-5718(02)00073-6.
    参考文献:10.1111/j.1471-4159.2004.02577.x
    摘要:Jiang J, Borisenko GG, Osipov A, Martin I, Chen R, Shvedova AA, Sorokin A, Tyurina YY, Potapovich A, Tyurin VA, Graham SH, Kagan VE. Arachidonic acid‐induced carbon‐centered radicals and phospholipid peroxidation in cyclo‐oxygenase‐2‐transfected PC12 cells. Journal of Neurochemistry. 2004 Jul 27;90(5):1036–49. doi: 10.1111/j.1471-4159.2004.02577.x.
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