CAS: 66176-93-0; Cimicifugoside
该化合物是在妇女健康方面,因为研究其在缓解热闪光和情绪波动等更年期症状方面的作用.Cimicifugoide ide 表现出抗炎和抗氧化性,使其对各种药用应用感兴趣.其行动机制被认为涉及调制荷尔蒙途径,尽管需要进一步研究以充分阐明其影响和安全特征.在生理特征方面,丙基福戈派典型是白色至白粉的白色,在水和酒精中溶解,在正常条件下稳定.与任何生物活性化合物一样,必须考虑在使用治疗时与其他药物的剂量和潜在互动.
- 英文名称Cimicifugoside
- 中文名称升麻素苷
- IUPAC名称(2a'R,4'S,6a'R,7a'S,9'R,9a'R,9b'R,10'R,13a'S,14a'S)-4-hydroxy-3',3',5,9a',10',14a'-hexamethyl-4'-(((2S,3R,4S,5R)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl)oxy)-2',2a',3',5',6',8',9',9a',9b',10',11',13a',14',14a'-tetradecahydro-4'H,7'H-3,6-dioxaspiro[bicyclo[3.1.0]hexane-2,12'-cyclopropa[1',8a']naphtho[2',1':4,5]indeno[2,1-b]pyran]-9'-yl acetate
- 其它别名Cimicifugoside
- CAS编号66176-93-0
- MFCD编号:MFCD32200154
- 分子式:C37H54O11分子量:674.83
- 产品CID: 1642896
- 产品分类生物化工 → 中草药成分
物理性质
MSDS等安全信息
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专利信息
专利号:US-8263755-B2
优先权日:2006-11-20
标题:Synthesis of compounds useful as modulators of amyloid-beta production
发明人：FINDEIS MARK A
权利人:FINDEIS MARK A; SATORI PHARMACEUTICALS INC
摘要:As described herein, the present invention provides methods for preparing compounds useful for treating or lessening the severity of a neurodegenerative disorder. The present invention also provides methods of treating or lessening the severity of such disorders wherein said method comprises administering to a patient a compound of the present invention, or composition thereof. Said method is useful for treating or lessening the severity of, for example, Alzheimer's disease.
专利号:US-2013059804-A1
优先权日:2006-11-20
标题:Synthesis of compounds useful as modulators of amyloid-beta production
专利号:EP-2073638-A2
优先权日:2006-11-20
标题:Synthesis of compounds useful as modulators of amyloid-beta production
专利号:CA-2670284-A1
优先权日:2006-11-20
标题:Synthesis of compounds useful as modulators of amyloid-beta production
专利号:EP-2073638-B1
优先权日:2006-11-20
标 题 :Synthesis of compounds useful as modulators of amyloid-beta production
专利号:WO-2008136863-A2
优先权日:2006-11-20
标题 :Synthesis of compounds useful as modulators of amyloid-beta production
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品牌试剂参考报价(招募中)
📌 第三方产品分析报告
合成参考文献
参考文献:10.5281/zenodo.5794106
摘要:The LOTUS Initiative for Open Natural Products Research: frozen dataset union wikidata (with metadata) | DOI:10.5281/zenodo.5794106
参考文献:10.1016/j.jpba.2011.11.029
摘要:Wang Y, Sha C, Liu W, Gai Y, Zhang H, Qu H, Wang W. Simultaneous determination of cimicifugoside H-2, cimicifugoside H-1, 23-epi-26-deoxyactein, cimigenol xyloside and 25-O-acetylcimigenoside in beagle dog plasma by LC–MS/MS. Journal of Pharmaceutical and Biomedical Analysis. 2012 Mar;62():87–95. doi: 10.1016/j.jpba.2011.11.029.
参考文献:10.1021/np0700319.s001
摘要:Chlorination Diversifies Cimicifuga racemosa Triterpene Glycosides. (). doi: 10.1021/np0700319.s001.
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