CAS: 5731-13-5; 4-Ethyl-[1,1-Biphenyl]-4-Carboxylic Acid

该化合物是一种有机化合物,其特征是其联苯结构,由两个联苯环组成,由一个单一债券连接;一个乙基组存在于一个苯环的副位置,另一个环的副位置,一个碳酸功能组(-COOH)存在于另一个环的副位置,这助长了其化学特性;该化合物通常是在室内温度下一种白色到非白色的固体,在有机溶剂中溶解,而其溶液在水中的溶解性则因联苯结构的疏水性而受到限制; 箱酸组具有酸性,使其能够参与各种化学反应,例如酯化和恐吓; 此外,4'乙基苯-4-碳酸可能展示生物活动,从而引起对制药和材料科学研究的兴趣;其结构特征和功能组表明,有机合成和作为生产更复杂的化学实体的中间体,其潜在用途是有机合成.

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CAS号586-76-5 对溴苯甲酸 | CAS号63139-21-9 对乙基苯硼酸 | CAS号619-58-9 对碘苯甲酸 | CAS号22873-28-5 4-苯乙基溴化镁 | CAS号128860-87-7 2-(4'-acetylbip... | CAS号852-38-0 2-(4-联苯基)-5-苯基恶二唑 | CAS号5730-92-7 4-乙酰基-4-乙基联苯 | CAS号92-91-1 4-联苯乙酮 | CAS号92-52-4 联苯 | CAS号5707-44-8 4-乙基联苯 | CAS号92119-00-1 4'-ethyl-biphen...

合成工艺路线路线简述

    4'-乙基-4-氰基联苯置于sodium Hydroxide体系中,化学反应生成 对乙基联苯甲酸
    参考文献:De2535046
    标题:De2535046

    海关参考信息

    专利信息


    专利号:WO-2006079916-A1
    优先权日:2005-01-26
    标 题 :Thieno [2,3-d] pyrimidine compounds as inhibitors of adp-mediated platelets aggregation
    发明人:ENNIS MICHAEL DALTON; KORTUM STEVEN WADE; RAHMAN HAYAT; SCHWEITZER BARBARA ANN; TENBRINK RUTH ELIZABETH
    权利人:PHARMACIA & UPJOHN CO LLC; ENNIS MICHAEL DALTON; KORTUM STEVEN WADE; RAHMAN HAYAT; SCHWEITZER BARBARA ANN; TENBRINK RUTH ELIZABETH
    摘要:Compounds and pharmaceutically acceptable salts of the compounds are disclosed, wherein the compounds have the structure of Formula (I): wherein A1, A2, A3, A4, A5, A6, A7, A8, X4, X6, R2, R4, R5, and R6 are as defined in the detailed description of the invention. Corresponding pharmaceutical compositions, methods of treatment, methods of synthesis, and intermediates are also disclosed.

    专利号:US-9217012-B2
    优先权日:2009-04-08
    标题 :Inhibitors of protein tyrosine phosphatases
    发明人:ZHANG ZHONG-YIN; ZHANG SHENG
    权利人:ZHANG ZHONG-YIN; ZHANG SHENG; UNIV INDIANA RES & TECH CORP
    摘要:Disclosed herein are compounds that selectively inhibit members of the PTP family of enzymes. Synthesized compounds demonstrated selective inhibition of TC-PTP. Also provided are methods of using the compounds and formulations containing the compounds. Also described is a fluorescence-tagged combinatorial library synthesis and screening method. And methods of using these compounds to effect enzyme activity both in cells and in vitro as well as method of using these compounds to treat diseases in human and animals.

    专利号:US-7671085-B2
    优先权日:2002-11-15
    标 题 :Non-steroidal farnesoid X receptor modulators and methods for the use thereof
    发明人:DOWNES MICHAEL R; EVANS RONALD M
    权利人:SALK INST FOR BIOLOGICAL STUDI
    摘要:The efficient regulation of cholesterol synthesis, metabolism, acquisition, and transport is an essential component of lipid homeostasis. The farnesoid X receptor (FXR) is a transcriptional sensor for bile acids, the primary product of cholesterol metabolism. Accordingly, the development of potent, selective, small molecule agonists, partial agonists, and antagonists of FXR would be an important step in further deconvoluting FXR physiology. In accordance with the present invention, the identification of novel potent FXR activators is described. Two derivatives of invention compounds, bearing stilbene or biaryl moieties, contain members that are the most potent FXR agonists reported to date in cell-based assays. These compounds are useful as chemical tools to further define the physiological role of FXR as well as therapeutic leads for the treatment of diseases linked to cholesterol, bile acids and their metabolism and homeostasis.

    专利号:CN-102850263-B
    优先权日:2012-10-10
    标题 :A kind of photomagnetically controllable liquid crystal compound containing Schiff base structure in the terminal group of alkyl biphenyl and its synthesis method

    专利号:CN-102850263-A
    优先权日:2012-10-10
    标 题 :A kind of photomagnetically controllable liquid crystal compound containing Schiff base structure in the terminal group of alkyl biphenyl and its synthesis method
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    合成参考文献


    参考文献:10.2116/analsci.20.717
    摘要:Zhang T, Liang Y, Li B, Cui H, Gong F. Systemic analysis of structures and contents of nitrogen-containing compounds and other non-hydrocarbons in crude oils in conjunction with chemometric resolution technique. Anal Sci. 2004 Apr;20(4):717–24. doi: 10.2116/analsci.20.717.
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