CAS: 4630-82-4; Methyl Cyclohexanecarboxylate

相似化合物

100-49-2 98-89-5 4630-82-4

上下游产品

benzoic acid methyl ester 2-methoxybenzoic acid methyl ester methyl cyclohexanecarboximidate hydr°Chloride methanol2-cyclohexyl-2-propanol methyl 3-cyclohexyl-3-oxopropionate (4))-methanHydroxy-cyclohexyl-bis-(biphenylyl-(4))-methan cyclohexylcarboxamide

苯甲酸甲酯置于氢气体系中,用 叔丁醇 作为反应溶剂,化学反应 24.0H,以92%的收率获得产物环己甲酸甲酯
参考文献:钴-纳米颗粒催化芳烃的高效选择性加氢
标题:钴-纳米颗粒催化芳烃的高效选择性加氢
摘要:开发用于芳烃加氢的廉价且实用的催化剂对于该常规原料的未来增值是关键.在这里,我们报道了负载在二氧化硅上的钴纳米颗粒作为此类反应的选择性和一般催化剂的发展.通过在商业二氧化硅上组装钴-均苯四酸-哌嗪配位聚合物并随后进行热解来制备特定的纳米颗粒.应用最佳的纳米催化剂,在工业上可行和可扩展的条件下,选择性地氢化工业本体,取代的和官能化的芳烃以及多环芳烃,以获得基于环己烷的化合物.提出了该氢化方法在液体有机氢载体中h 2的储存的适用性.
DOI:10.1021/acscatal.9B02193

专利信息

专利号:EP-1724260-B1
优先权日:2005-05-06
标题:Process for the synthesis of (2S, 3aR, 7aS)octahydroindole-2-carboxylic acid and its conversion to trandolapril
发明人：AKHTAR HAIDER; RAMESH BABU POTLURI; VENKATA SUBHRAMANIAN HARIHARAK; HARI PRASSAD KODALI
权利人:SOCHINAZ SA
摘要:The present invention describes a novel method for the synthesis of (2S,3aR,7aS)-octahydroindole-2-carboxylic acid of formula III nusing a new intermediate of formula II nand conversion of the product of formula-III to trandolapril of formula I

专利号:US-2023303611-A1
优先权日:2022-01-21
标题:Synthesis of an antiviral azasugar triphosphate
发明人：KOTIAN PRAVIN L; Dang zhao; WU MINWAN
权利人:BIOCRYST PHARM INC
摘要:Provided are methods of making the active 5′-triphosphate form of galidesivir (compound 1) and the active 5′-triphosphate form of azasugar nucleoside analogues (compound 2):a potent anti-viral compound useful for broad spectrum treatment, suppression, and prevention of viral infections. The syntheses of compound 1 and compound 2 can be achieved via selective formation of protected intermediate 1b and protected intermediate 2b, respectively:

专利号:US-2024208900-A1
优先权日:2021-04-16
标题 :Synthesis of dimethyl-c17-32-alkyl sulfonium salts
发明人：STROOT JOERG; ZHERSH SERHII; RIPENKO VASYL
权利人:HELM AG
摘要:The invention relates to a process for the preparation of a dimethyl-C 17-32 -alkyl sulfonium salt, preferably a dimethyl-C 17-32 -alkyl sulfonium halide, more preferably a dimethyl-C 17-32 -alkyl sulfonium chloride, still more preferably dimethyl octadecyl sulfonium chloride, the process comprising the steps of: providing a mixture of a C 17-32 -alkyl halide and dimethyl sulfide; and reacting the C 17-32 -alkyl halide with the dimethyl sulfide.

专利号:US-8680294-B2
优先权日:2009-07-29
标题 :Enantio- and stereo specific synthesis of β-amino-α-hydroxy amides
发明人：TRAVERSE JOHN; LEONG WILLIAM M; MILLER STEVEN P; ALBANEZE-WALKER JENNIFER; HUNTER THOMAS J; WANG LIJUN; LIAO HONGBIAO; ARASAPPAN ASHOK; TRZASKA SCOTT T; SMITH RANDI M; LEKHAL AZZEDDINE; BOGEN STEPHANE L; KONG JIANSHE; BENNETT FRANK; NJOROGE F GEORGE; POIRIER MARC; KUO SHEN-CHUN; CHEN YONGGANG; MATTHEWS KENNETH S; DEMONCHAUX PATRICE; FERREIRA AMADEO
权利人:TRAVERSE JOHN; LEONG WILLIAM M; MILLER STEVEN P; ALBANEZE-WALKER JENNIFER; HUNTER THOMAS J; WANG LIJUN; LIAO HONGBIAO; ARASAPPAN ASHOK; TRZASKA SCOTT T; SMITH RANDI M; LEKHAL AZZEDDINE; BOGEN STEPHANE L; KONG JIANSHE; BENNETT FRANK; NJOROGE F GEORGE; POIRIER MARC; KUO SHEN-CHUN; CHEN YONGGANG; MATTHEWS KENNETH S; DEMONCHAUX PATRICE; FERREIRA AMADEO; MERCK SHARP & DOHME
摘要:Processes useful for the preparation of a Compound of Formula I: Formula (I). Intermediates useful for the preparation of the compound of Formula I, and processes useful for preparing said intermediates are disclosed.

专利号:US-6011171-A
优先权日:1996-08-14
标 题 :Process for synthesis of tertiary carboxylic acids and the esters thereof
发明人：XU QIANG; SOUMA YOSHIE
权利人:JIRO HIRAISHI DIRECTOR GENERAL
摘要:The present invention provides a process for synthesizing tertiary carboxylic acids or the esters thereof having one or two more carbon atoms than the raw material has, comprising reacting in a strong acid (e.g., sulfuric acid, sulfuric acid-phosphoric acid, hydrogen fluoride, fluorosulfuric acid, boron trifluoride.water complex and trifluoromethanesulfonic acid) a raw material compound (i.e., olefin, alcohol, diene, diol or saturated hydrocarbon) with carbon monoxide in the presence of a specific metal carbonyl catalyst (i.e., platinum carbonyl catalyst, palladium carbonyl catalyst and gold dicarbonyl catalyst). The metal carbonyl catalyst is formed by reacting in a strong acid at least one specific metal compounds (e.g., platinum compound such as platinum (II, IV) oxide, platinum (II, IV) hydroxide, a platinum powder, etc.; palladium compound such as palladium (II, III, IV) oxide, palladium (II) hydroxide, palladium (II) sulfate, palladium (II) carboxylate, a palladium powder, etc.; and gold compound such as gold (I, III) oxide, gold (I, III) hydroxide, a gold powder, etc.) with carbon monoxide.

专利号:US-4518602-A
优先权日:1982-10-07
标题 :Vinyl carboxylic acid derivatives, their production and use as inhibitors of thromboxane synthetase
发明人：TERAO SHINJI; NISHIKAWA KOHEI
权利人:TAKEDA CHEMICAL INDUSTRIES LTD
摘要:Novel compound of the formula: wherein R1 is a pyridyl group; R2 is a phenyl, thienyl, furyl, naphthyl, benzothienyl or pyridyl group which may have as a substituent a lower alkoxy, a lower alkyl, a halogen, trifluoromethyl, a lower alkenyl or methylenedioxy; R3 is hydrogen, benzyl or a lower alkyl; one of R4 and R5 is hydrogen or a lower alkyl, and the other is an aryloxy, or lower aliphatic hydrocarbon, an alicyclic hydrocarbon having not more than 6 carbon atoms or an aromatic group which may have a substituent, or a group represented by the formula, -S(O)m-R6 (in which R6 is phenyl or a lower alkyl group; m is an integer of 0 to 2), or R4 and R5 each combine with the other to represent one alkylene group; n is an integer of 2 to 6, or a pharmaceutically acceptable salt thereof has a selective inhibitory action on bio-synthesis of thromboxane A2(TXA2) and an effect of enhancing the production of prostaglandin I2(PGI2), and can be used in mammals for to prevention and treatment of arterial thrombosis caused by platelet aggregation or ischemic diseases caused by vasospasms in cardiac, cerebral and peripheral circulatory system (e.g. cardian infarction, apoplexy, infarct of blood vessels in kidney, lung and other organs, pectic ulcer, etc.).