CAS: 29684-56-8; Burgess Reagent

相似化合物

263719-76-2 174466-48-9 1803606-68-9

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CAS号36914-92-8 methyl N-chloro... | CAS号121-44-8 三乙胺 | CAS号1485-70-7 N-苄基苯甲酰胺 | CAS号17013-30-8 N-(benzylcarbam... | CAS号681-99-2 三丁基锡乙氰酸酯 | CAS号100073-20-9 (Tributyl(1-cyc... | CAS号22139-32-8 methyl N-hexylc... | CAS号90222-26-7 methyl N-(cyclo... | CAS号5817-70-9 苄基氨基甲酸甲酯

N-氯磺酰基氨基甲酸甲酯,三乙胺 以 甲苯,苯 用作溶剂,化学反应 0.1H,以21.7 G的收率获得伯吉斯试剂
参考文献:Burgess试剂促进了dmso中的酒精氧化
标题:Burgess试剂促进了dmso中的酒精氧化
摘要:历史上已经发现burgess试剂([[甲氧基羰基氨磺酰基]三乙基氢氧化铵]可用作脱水剂.本文中,我们表明,在二甲亚砜的存在下,伯吉斯试剂可以高效,迅速地促进各种伯醇和仲醇氧化成其相应的醛和酮,且收率极高,且温度适中,并且可以与其他方法结合使用.转化(例如wittig烯烃化).提出了一种类似于针对pfitzner-Moffatt和swern氧化所描述的机理.
Doi:10.1021/acs.Joc.6B02629

专利信息

专利号:US-6849743-B2
优先权日:1997-08-15
标 题 :Synthesis of clasto-lactacystin β-lactone and analogs thereof
发明人：SOUCY FRANCOIS; FLAMONDON LOUIS; BEHNKE MARK; ROUSH WILLIAM
权利人:MILLENNIUM PHARM INC
摘要:The present invention is directed to an improved synthesis of clasto-lactacystin-β-lactone, and analogs thereof, that proceeds in fewer steps and in much greater overall yield than syntheses described in the prior art. The synthetic pathway relies upon a novel stereospecific synthesis of an oxazoline intermediate and a unique stereoselective addition of a formyl amide to the oxazoline. Also described are novel clasto-lactacystin-β-lactones, and analogs thereof and their use as proteasome inhibitors.

专利号:WO-2025108575-A1
优先权日:2023-11-21
标 题:Methods of selective deprotection and synthesis of transhydrindane- skeleton-based compounds
发明人：HUBER FLORIAN MAURITIUS ERASMUS
权利人:ROCHE DIAGNOSTICS GMBH
摘要:The present invention relates to methods of selectively deprotecting a transhydrindane-skeleton-based compound comprising at least two different silyl ether groups. The present invention further relates to methods of synthesizing a Vitamin D molecule and to Vitamin D molecules obtainable by such processes. Furthermore, the present invention relates to a compound according to formula (I) comprising two different silyl ether groups, its use in the synthesis of Vitamin D molecules and to methods of producing such a compound.

专利号:WO-9747313-A1
优先权日:1996-06-10
标题:Total synthesis of bacitracin polypetides
发明人：GRIFFIN JOHN H; MCDOUGAL PATRICK G
权利人:UNIV LELAND STANFORD JUNIOR
摘要:Methods for the total synthesis of bacitracin-type polypeptides are described, as well as useful analogs of bacitracin A, and treatment of bacterial infection using such analogs.

专利号:US-6342619-B2
优先权日:1999-04-01
标题:Synthesis of conjugated fatty acid
发明人：SEIDEL MICHAEL C
摘要:A synthesis process is disclosed for producing a conjugated fatty acid at specified temperature in high yield, including providing an ester of a fatty acid having somewhere in its carbon chain a chain of four carbon atoms such that carbon one bears one hydrogen and one hydroxyl group, carbon two bears two hydrogen atoms, and a double bond is positioned between carbon three and carbon four and reacting with a chloride selected from the group consisting of toluenesulfonyl chloride, methanesulfonyl chloride, benzenesulfonyl chloride, alkylsulfonyl chloride, and arylsulfonyl chloride at a temperature in the range of 10° C.-100° C., preferably 20° C.-50° C. The synthesis process provides a conjugated fatty acid formed from the ester reacted with diazabicycloundecene. In one aspect, the ester is formed in a pyridine solvent. In one aspect, a mesylate is formed with mesyl chloride in acetonitrile and triethyl amine. In one aspect, the reaction with diazabicyclo-undecene is conducted in a polar, non-hydroxylic solvent of acetonitrile to form a preferred isomer at the specified temperature in high yield.

专利号:US-6160141-A
优先权日:1997-02-18
标 题 :Synthesis of conjugated eicosadienoic acid
发明人：SEIDEL MICHAEL C
摘要:A synthesis process for producing 11-cis, 13-trans eicosadienoic acid at room temperature in high yield is disclosed, including providing a tosylate or mesylate of a methyl lesquerolate and 11-cis, 13-trans eicosadienoic acid formed when the tosylate or mesylate reacts with diazabicyclo-undecene. In one aspect, the tosylate of the methyl lesquerolate is formed with tosyl chloride in a pyridine solvent. In one aspect, the mesylate of the methyl lesquerolate is formed with mesyl chloride in acetonitrile and triethyl amine. In one aspect, the tosylate or mesylate is reacted with diazabicyclo-undecene in a polar, non-hydroxylic solvent of acetonitrile to form the preferred isomer of 11-cis, 13-trans eicosadienoic acid at room temperature in high yield.

专利号:US-5892074-A
优先权日:1997-02-18
标 题:Synthesis of conjugated linoleic acid (CLA)
发明人：SEIDEL MICHAEL C
摘要:A synthesis process for producing 9-cis, 11-trans octadecadienoic acid at room temperature in high yield is disclosed, including providing a tosylate or mesylate of a methyl ester of ricinoleic acid and 9-cis, 11-trans octadecadienoic acid formed when the tosylate or mesylate reacts with diazabicyclo-undecene. In one aspect, the tosylate of the methyl ester of ricinoleic acid is formed with tosyl chloride in a pyridine solvent. In one aspect, the mesylate of the methyl ester of ricinoleic acid is formed with mesyl chloride in acetonitrile and triethyl amine. In one aspect, the tosylate or mesylate is reacted with diazabicyclo-undecene in a polar, non-hydoxylic solvent of acetonitrile to form the preferred isomer of 9-cis, 11-trans octadecadienoic acid at room temperature in high yield.