CAS: 2402-78-0; 2,6-Dichloropyridine

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16063-69-7 26452-80-2 98027-84-0

上下游产品

CAS号109-09-1 2-氯吡啶 | CAS号2587-00-0 2,6-二氯代吡啶-N-氧化物 | CAS号17228-64-7 2-氯-6-甲氧基吡啶 | CAS号626-05-1 2,6-二溴吡啶 | CAS号2039-85-2 3-氯苯乙烯 | CAS号1073-67-2 对氯苯乙烯 | CAS号873-66-5 反-β-甲基苯乙烯 | CAS号292638-84-7 phenylene-ethylene | CAS号42144-78-5 2-氯-6-乙氧基吡啶 | CAS号29449-73-8 2-(苄氧基)-6-氯吡啶 | CAS号108122-25-4 1-(6-乙氧基-2-哌啶)哌嗪 | CAS号1060801-42-4 2-氯-6-二甲胺基吡啶 | CAS号4411-80-7 6,6′-二甲基-2,2′-联吡啶 | CAS号33777-92-3 2,6-bis(6-methy... | CAS号366-18-7 2,2'-联吡啶 | CAS号57154-73-1 6-Methyl-2,2':6... | CAS号56100-22-2 6-甲基-2,2'-联吡啶 | CAS号53710-17-1 2,6-二碘吡啶 | CAS号258506-66-0 2-氯-6-碘吡啶

2-氯吡啶置于正丁基锂,Buli-Lidmae,六氯乙烷体系中,用 正己烷,四氢呋喃 用作溶剂,化学反应 2.0H,以74%的收率获得2,6-二氯吡啶
参考文献:由buli-Me(2)n(ch(2))(2)oli介导的2-氯吡啶异常c-6锂化.新获得6-功能-2-氯吡啶和氯双杂环.
标题:由buli-Me(2)n(ch(2))(2)oli介导的2-氯吡啶异常c-6锂化.新获得6-功能-2-氯吡啶和氯双杂环.
摘要:2-氯吡啶与烷基ith的反应通常导致亲核加成,导致氯原子的损失,同时使用lda获得排他性的直接邻位金属化.在此表明,Buli-Me(2)n(ch(2))(2)oli(buli-Lidmae)超碱促进了前所未有的区域选择性c-6锂化.该方法已成功地用于制备潜在有用的氯化吡啶二酮和双杂环合成子.
Doi:10.1021/ol005538O

专利信息

专利号:WO-2009018504-A1
优先权日:2007-08-01
标题 :Process for the synthesis of diaminopyridine and related compounds
发明人：RITTER JOACHIM C
权利人:DU PONT; RITTER JOACHIM C
摘要:A process is provided for the synthesis of a diaminopyridine, such as 2,6-diaminopyridine and related compounds, which are used industrially as compounds and as components in the synthesis of a variety of useful materials. The synthesis proceeds by means of a chlorine-ammonia displacement in the presence of a copper source.

专利号:US-8569560-B2
优先权日:2006-10-13
标题 :Synthesis of terminal alkenes from internal alkenes via olefin metathesis
发明人：SCHRODI YANN; PEDERSON RICHARD L; KAIDO HIROKI; TUPY MICHAEL J
权利人:ELEVANCE RENEWABLE SCIENCES
摘要:This disclosure relates generally to olefin metathesis, and more particularly relates to the synthesis of terminal alkenes from internal alkenes using a cross-metathesis reaction catalyzed by an olefin metathesis catalyst. According to one aspect, for example, a method is provided for synthesizing a terminal olefin, the method comprising contacting, in the presence of a ruthenium alkylidene metathesis catalyst, an olefinic substrate comprised of at least one internal olefin with a cross metathesis partner comprised of an alpha olefinic reactant, under reaction conditions effective to allow cross-metathesis to occur, wherein the reaction conditions include a reaction temperature of at least 35° C. The methods, compositions, reactions and reaction systems herein disclosed have utility in the fields of catalysis, organic synthesis, and industrial chemistry.

专利号:US-9255117-B2
优先权日:2006-07-13
标题 :Synthesis of terminal alkenes from internal alkenes and ethylene via olefin metathesis
发明人：SCHRODI YANN
权利人:MATERIA INC
摘要:This invention relates generally to olefin metathesis, and more particularly relates to the synthesis of terminal alkenes from internal alkenes using a cross-metathesis reaction catalyzed by a selected olefin metathesis catalyst. In one embodiment of the invention, for example, a method is provided for synthesizing a terminal olefin, the method comprising contacting an olefinic substrate comprised of at least one internal olefin with ethylene, in the presence of a metathesis catalyst, wherein the catalyst is present in an amount that is less than about 1000 ppm relative to the olefinic substrate, and wherein the metathesis catalyst has the structure of formula (II) n nwherein the various substituents are as defined herein. The invention has utility, for example, in the fields of catalysis, organic synthesis, and industrial chemistry.

专利号:US-6271379-B1
优先权日:2000-03-08
标题:Intermediates useful for the synthesis of huperzine A
发明人：TUECKMANTEL WERNER; KOZIKOWSKI ALAN P
权利人:UNIV GEORGETOWN
摘要:Intermediates useful for the synthesis of huperzine A represented by the structures below, n and methods for their synthesis, wherein: n R 1 is lower alkyl, benzyl, or substituted benzyl; n X is a suitable leaving group; n Y is an electron withdrawing group that can subsequently be converted into an amino group; n one broken line is present as a carbon—carbon bond and the other broken line is absent, where the broken line forms an unconjugated carbon—carbon double bond, which double bond may be endocyclic whereby n is 3 or the double bond may be exocyclic whereby n is 2.

专利号:US-7148356-B2
优先权日:2001-07-13
标题:Process for the catalytic synthesis of biaryls and polymers from aryl compounds
发明人：SMITH III MILTON R; MALECZKA ROBERT E
权利人:UNIV MICHIGAN STATE
摘要:A process for producing organic substituted aromatic or heteroaromatic compounds including biaryl and biheteroaryl compounds in a two-step reaction. In the first step, the aromatic or heteroaromatic compound is borylated in a reaction comprising a borane or diborane reagent (any boron reagent where the boron reagent contains a B—H, B—B or B—Si bond) and an iridium or rhodium catalytic complex. In the second step, a metal catalyst catalyzes the formation of the organic substituted aromatic or heteroaromatic compound from the borylated compound and an electrophile such as an aryl or organic halide, triflate (OSO 2 CF 3 ), or nonaflate (OSO 2 C 4 F 9 ). The steps in the process can be performed in a single reaction vessel or in separate reaction vessels. The present invention also provides a process for synthesis of complex polyphenylenes starting from halogenated aromatic compounds.

专利号:US-6946533-B2
优先权日:2002-08-01
标 题 :Synthesis of macrocyclic polymers by ring insertion polymerization of cyclic olefin monomers
发明人：GRUBBS ROBERT; BIELAWSKI CHRIS; BENITEZ DIEGO
权利人:CALIFORNIA INST OF TECHN
摘要:A method for synthesizing cyclic polymers using transition metal alkylidene complexes as reaction catalysts is provided, wherein the complexes contain a cyclic group. Polymerization is carried out on the catalyst, using cyclic olefin monomers that undergo ring insertion polymerization, and no linear intermediates are generated. Following completion of polymerization, the cyclic polymer detaches from the complex via an intramolecular chain transfer reaction and the catalytic complex is regenerated. The invention also provides novel transition metal alkylidene complexes useful as catalysts in the aforementioned process, as well as novel cyclic hydrocarbons.